12 items (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JAK2	Tyrosine-protein kinase. (1132 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform X1. (605 aa)
	GHR	Growth hormone receptor. (681 aa)
	PRL	Prolactin. (248 aa)
	ENSVVUP00000005276	annotation not available (161 aa)
	ENSVVUP00000005490	annotation not available (72 aa)
	LOC112920600	Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (190 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	SKP1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	PRLR	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (625 aa)
	SH2B1	SH2B adapter protein 1 isoform X1. (760 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CUL1	ENSVVUP00000000785	ENSVVUP00000022561	F-box/WD repeat-containing protein 1A isoform X1.	Cullin-1; Belongs to the cullin family.	0.998
BTRC	ENSVVUP00000005276	ENSVVUP00000000785	ENSVVUP00000005276	F-box/WD repeat-containing protein 1A isoform X1.	annotation not available	0.864
BTRC	ENSVVUP00000005490	ENSVVUP00000000785	ENSVVUP00000005490	F-box/WD repeat-containing protein 1A isoform X1.	annotation not available	0.864
BTRC	GHR	ENSVVUP00000000785	ENSVVUP00000002153	F-box/WD repeat-containing protein 1A isoform X1.	Growth hormone receptor.	0.426
BTRC	RBX1	ENSVVUP00000000785	ENSVVUP00000009233	F-box/WD repeat-containing protein 1A isoform X1.	E3 ubiquitin-protein ligase RBX1 isoform X2.	0.995
BTRC	SKP1	ENSVVUP00000000785	ENSVVUP00000029265	F-box/WD repeat-containing protein 1A isoform X1.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.985
CUL1	BTRC	ENSVVUP00000022561	ENSVVUP00000000785	Cullin-1; Belongs to the cullin family.	F-box/WD repeat-containing protein 1A isoform X1.	0.998
CUL1	ENSVVUP00000005276	ENSVVUP00000022561	ENSVVUP00000005276	Cullin-1; Belongs to the cullin family.	annotation not available	0.975
CUL1	ENSVVUP00000005490	ENSVVUP00000022561	ENSVVUP00000005490	Cullin-1; Belongs to the cullin family.	annotation not available	0.975
CUL1	JAK2	ENSVVUP00000022561	ENSVVUP00000009883	Cullin-1; Belongs to the cullin family.	Tyrosine-protein kinase.	0.567
CUL1	PRL	ENSVVUP00000022561	ENSVVUP00000003572	Cullin-1; Belongs to the cullin family.	Prolactin.	0.569
CUL1	PRLR	ENSVVUP00000022561	ENSVVUP00000030233	Cullin-1; Belongs to the cullin family.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.555
CUL1	RBX1	ENSVVUP00000022561	ENSVVUP00000009233	Cullin-1; Belongs to the cullin family.	E3 ubiquitin-protein ligase RBX1 isoform X2.	0.999
CUL1	SKP1	ENSVVUP00000022561	ENSVVUP00000029265	Cullin-1; Belongs to the cullin family.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.999
ENSVVUP00000005276	BTRC	ENSVVUP00000005276	ENSVVUP00000000785	annotation not available	F-box/WD repeat-containing protein 1A isoform X1.	0.864
ENSVVUP00000005276	CUL1	ENSVVUP00000005276	ENSVVUP00000022561	annotation not available	Cullin-1; Belongs to the cullin family.	0.975
ENSVVUP00000005276	JAK2	ENSVVUP00000005276	ENSVVUP00000009883	annotation not available	Tyrosine-protein kinase.	0.435
ENSVVUP00000005276	PRLR	ENSVVUP00000005276	ENSVVUP00000030233	annotation not available	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.	0.433
ENSVVUP00000005276	RBX1	ENSVVUP00000005276	ENSVVUP00000009233	annotation not available	E3 ubiquitin-protein ligase RBX1 isoform X2.	0.971
ENSVVUP00000005490	BTRC	ENSVVUP00000005490	ENSVVUP00000000785	annotation not available	F-box/WD repeat-containing protein 1A isoform X1.	0.864