STRINGSTRING
PSMB2 PSMB2 TM7SF3 TM7SF3 PSMC6 PSMC6 PSMA3 PSMA3 ANAPC2 ANAPC2 ENSVVUP00000041103 ENSVVUP00000041103 PSME2 PSME2 PSME1 PSME1 ENSVVUP00000040094 ENSVVUP00000040094 ANAPC1 ANAPC1 RB1 RB1 UBE2E1 UBE2E1 AURKB AURKB PSMB6 PSMB6 FAM89B FAM89B CCNA1 CCNA1 BUB1B BUB1B ENSVVUP00000036620 ENSVVUP00000036620 UBC UBC ENSVVUP00000033526 ENSVVUP00000033526 PSME3 PSME3 PSMC3 PSMC3 ANAPC16 ANAPC16 CDK2 CDK2 ENSVVUP00000030237 ENSVVUP00000030237 CDC14A CDC14A ENSVVUP00000029975 ENSVVUP00000029975 ENSVVUP00000029378 ENSVVUP00000029378 SKP1 SKP1 CDC20B CDC20B PSMD11 PSMD11 ENSVVUP00000027737 ENSVVUP00000027737 PSMA6 PSMA6 PSMB11 PSMB11 PSMB5 PSMB5 ENSVVUP00000026875 ENSVVUP00000026875 ENSVVUP00000026085 ENSVVUP00000026085 ANAPC11 ANAPC11 ENSVVUP00000000145 ENSVVUP00000000145 UBE2E2 UBE2E2 PSMD5 PSMD5 ENSVVUP00000016274 ENSVVUP00000016274 ENSVVUP00000016277 ENSVVUP00000016277 PSMD2 PSMD2 PSMB10 PSMB10 PSMD4 PSMD4 PSMB4 PSMB4 ENSVVUP00000017628 ENSVVUP00000017628 FBXO43 FBXO43 PSMC5 PSMC5 PSMD12 PSMD12 BUB3 BUB3 PSMA2 PSMA2 CCNB1 CCNB1 PSMB1 PSMB1 ENSVVUP00000009448 ENSVVUP00000009448 UBE2S UBE2S ENSVVUP00000009638 ENSVVUP00000009638 PLK1 PLK1 PSMC4 PSMC4 CDC27 CDC27 LOC112911081 LOC112911081 LOC112919437 LOC112919437 ENSVVUP00000005490 ENSVVUP00000005490 LOC112923316 LOC112923316 ENSVVUP00000005276 ENSVVUP00000005276 PTTG1 PTTG1 ENSVVUP00000004945 ENSVVUP00000004945 FZR1 FZR1 PSMA5 PSMA5 FBXO5 FBXO5 ENSVVUP00000010304 ENSVVUP00000010304 PSME4 PSME4 PSMA4 PSMA4 UBA52 UBA52 PSMF1 PSMF1 UBE2D1 UBE2D1 CDC20 CDC20 CDK1 CDK1 ANAPC10 ANAPC10 ENSVVUP00000012574 ENSVVUP00000012574 ENSVVUP00000012585 ENSVVUP00000012585 KIAA2012 KIAA2012 PSMC1 PSMC1 CDC23 CDC23 PSMD14 PSMD14 NEK2 NEK2 PSMB7 PSMB7 RPS27A RPS27A PSMD10 PSMD10 ENSVVUP00000014607 ENSVVUP00000014607 SKP2 SKP2 ENSVVUP00000014764 ENSVVUP00000014764 ENSVVUP00000016245 ENSVVUP00000016245 PSMD1 PSMD1 ENSVVUP00000035544 ENSVVUP00000035544 CREBZF CREBZF PSMD8 PSMD8 CCNA2 CCNA2 ANAPC4 ANAPC4 CDC16 CDC16 LOC112921925 LOC112921925 ANAPC15 ANAPC15 PSMB9 PSMB9 PSMB8 PSMB8 ENSVVUP00000033877 ENSVVUP00000033877 LOC112910913 LOC112910913 ENSVVUP00000033527 ENSVVUP00000033527 ENSVVUP00000023844 ENSVVUP00000023844 ENSVVUP00000023775 ENSVVUP00000023775 AURKA AURKA PSMD7 PSMD7 PSMD13 PSMD13 ANAPC5 ANAPC5 CUL1 CUL1 ANAPC7 ANAPC7 UBE2C UBE2C PSMA7 PSMA7 CDK3 CDK3 PSMD6 PSMD6 PSMC2 PSMC2 ENSVVUP00000003182 ENSVVUP00000003182 AURKC AURKC CDC26 CDC26 PSMB3 PSMB3 PSMA8 PSMA8 PSMD3 PSMD3 BTRC BTRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB2Proteasome subunit beta. (189 aa)
TM7SF3Transmembrane 7 superfamily member 3. (568 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (836 aa)
ENSVVUP00000041103annotation not available (105 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSME1Proteasome activator complex subunit 1. (279 aa)
ENSVVUP00000040094annotation not available (128 aa)
ANAPC1Anaphase-promoting complex subunit 1. (1943 aa)
RB1Retinoblastoma-associated protein. (928 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
AURKBAurora kinase B isoform X3; Belongs to the protein kinase superfamily. (501 aa)
PSMB6Proteasome subunit beta. (239 aa)
FAM89BLeucine repeat adapter protein 25. (192 aa)
CCNA1cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa)
BUB1BMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1158 aa)
ENSVVUP00000036620annotation not available (157 aa)
UBCpolyubiquitin-C. (190 aa)
ENSVVUP00000033526annotation not available (137 aa)
PSME3Proteasome activator complex subunit 3. (247 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
ANAPC16Anaphase-promoting complex subunit 16 isoform X1. (110 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
ENSVVUP00000030237annotation not available (144 aa)
CDC14ADual specificity protein phosphatase CDC14A isoform X2. (611 aa)
ENSVVUP00000029975annotation not available (85 aa)
ENSVVUP00000029378annotation not available (285 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
CDC20BCell division cycle protein 20 homolog B isoform X1. (489 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (410 aa)
ENSVVUP00000027737annotation not available (222 aa)
PSMA6Proteasome subunit alpha type. (228 aa)
PSMB11Proteasome subunit beta. (327 aa)
PSMB5Proteasome subunit beta. (277 aa)
ENSVVUP00000026875annotation not available (107 aa)
ENSVVUP00000026085annotation not available (190 aa)
ANAPC11Anaphase-promoting complex subunit 11 isoform X1. (84 aa)
ENSVVUP00000000145annotation not available (84 aa)
UBE2E2Ubiquitin-conjugating enzyme E2 E2. (202 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (461 aa)
ENSVVUP00000016274annotation not available (188 aa)
ENSVVUP00000016277annotation not available (152 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (410 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
ENSVVUP00000017628annotation not available (263 aa)
FBXO43LOW QUALITY PROTEIN: F-box only protein 43. (694 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X1. (456 aa)
BUB3Mitotic checkpoint protein BUB3 isoform X2. (330 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (427 aa)
PSMB1Proteasome subunit beta. (294 aa)
ENSVVUP00000009448annotation not available (262 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
ENSVVUP00000009638annotation not available (374 aa)
PLK1Serine/threonine-protein kinase PLK. (607 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
CDC27Cell division cycle protein 27 homolog isoform X1. (825 aa)
LOC112911081Mitotic spindle assembly checkpoint protein MAD2A. (190 aa)
LOC112919437Proteasome subunit alpha type-1-like. (265 aa)
ENSVVUP00000005490annotation not available (72 aa)
LOC112923316Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
ENSVVUP00000005276annotation not available (161 aa)
PTTG1Securin. (207 aa)
ENSVVUP00000004945annotation not available (98 aa)
FZR1Fizzy-related protein homolog isoform X2. (571 aa)
PSMA5Proteasome subunit alpha type. (264 aa)
FBXO5F-box only protein 5. (448 aa)
ENSVVUP00000010304annotation not available (270 aa)
PSME4Proteasome activator complex subunit 4. (1823 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (418 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CDC20Cell division cycle protein 20 homolog. (525 aa)
CDK1LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (274 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (196 aa)
ENSVVUP00000012574annotation not available (262 aa)
ENSVVUP00000012585annotation not available (79 aa)
KIAA2012Uncharacterized protein KIAA2012 homolog. (1168 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
CDC23Cell division cycle protein 23 homolog isoform X1. (597 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
NEK2Serine/threonine-protein kinase Nek2. (444 aa)
PSMB7Proteasome subunit beta. (239 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
ENSVVUP00000014607annotation not available (200 aa)
SKP2S-phase kinase-associated protein 2. (436 aa)
ENSVVUP00000014764annotation not available (139 aa)
ENSVVUP00000016245annotation not available (152 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1037 aa)
ENSVVUP00000035544annotation not available (382 aa)
CREBZFCREB/ATF bZIP transcription factor isoform X1. (369 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (452 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (431 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (620 aa)
LOC112921925G2/mitotic-specific cyclin-B1-like; Belongs to the cyclin family. (382 aa)
ANAPC15Anaphase-promoting complex subunit 15 isoform X2. (133 aa)
PSMB9Proteasome subunit beta. (209 aa)
PSMB8Proteasome subunit beta. (306 aa)
ENSVVUP00000033877annotation not available (238 aa)
LOC112910913Ubiquitin-like. (77 aa)
ENSVVUP00000033527annotation not available (166 aa)
ENSVVUP00000023844annotation not available (87 aa)
ENSVVUP00000023775annotation not available (63 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (386 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
ANAPC5Anaphase-promoting complex subunit 5. (755 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
ANAPC7Anaphase-promoting complex subunit 7 isoform X1. (598 aa)
UBE2CUbiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
PSMA7Proteasome endopeptidase complex. (243 aa)
CDK3Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily. (305 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ENSVVUP00000003182annotation not available (261 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
CDC26Anaphase-promoting complex subunit CDC26 isoform X2. (125 aa)
PSMB3Proteasome subunit beta. (196 aa)
PSMA8Proteasome endopeptidase complex. (405 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.