STRINGSTRING
MAPK3 MAPK3 MAPK7 MAPK7 ATF1 ATF1 MAPK11 MAPK11 LYL1 LYL1 JUNB JUNB FNBP4 FNBP4 RPS6KA4 RPS6KA4 SRF SRF PPP2R5D PPP2R5D NAB1 NAB1 FOSL1 FOSL1 MAPK15 MAPK15 ID3 ID3 DUSP7 DUSP7 SGK1 SGK1 TRIB2 TRIB2 MAPKAPK2 MAPKAPK2 ASCL2 ASCL2 FOSB FOSB ENSVVUP00000005393 ENSVVUP00000005393 EGR3 EGR3 EGR4 EGR4 ID2 ID2 EGR2 EGR2 PPP2R1A PPP2R1A RRAD RRAD CHD4 CHD4 DUSP6 DUSP6 PPP4R1 PPP4R1 CREB1 CREB1 RPS6KA1 RPS6KA1 ENSVVUP00000017517 ENSVVUP00000017517 RPS6KA3 RPS6KA3 ARC ARC PPP2R1B PPP2R1B TRIB1 TRIB1 LOC112932177 LOC112932177 DUSP3 DUSP3 ELK1 ELK1 RELCH RELCH ENSVVUP00000024290 ENSVVUP00000024290 ASCL1 ASCL1 EGR1 EGR1 RPS6KA5 RPS6KA5 PPP4R4 PPP4R4 NAB2 NAB2 DUSP4 DUSP4 PPP2CB PPP2CB VRK3 VRK3 MAPK1 MAPK1 PPP2CA PPP2CA RPS6KA2 RPS6KA2 MAPK14 MAPK14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X2. (270 aa)
MAPK11Mitogen-activated protein kinase. (332 aa)
LYL1Protein lyl-1. (273 aa)
JUNBTranscription factor jun-B. (347 aa)
FNBP4LOW QUALITY PROTEIN: formin-binding protein 4. (1022 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (709 aa)
SRFSerum response factor isoform X1. (508 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (604 aa)
NAB1LOW QUALITY PROTEIN: NGFI-A-binding protein 1. (409 aa)
FOSL1Fos-related antigen 1 isoform X1. (268 aa)
MAPK15Mitogen-activated protein kinase. (601 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (464 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
TRIB2Tribbles homolog 2. (435 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (429 aa)
ASCL2Achaete-scute homolog 2. (197 aa)
FOSBProtein fosB isoform X1. (418 aa)
ENSVVUP00000005393annotation not available (155 aa)
EGR3Early growth response protein 3 isoform X3. (349 aa)
EGR4Early growth response protein 4 isoform X1. (589 aa)
ID2DNA-binding protein inhibitor ID-2. (196 aa)
EGR2E3 SUMO-protein ligase EGR2 isoform X1. (485 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
RRADGTP-binding protein RAD. (278 aa)
CHD4chromodomain-helicase-DNA-binding protein 4 isoform X3. (1984 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (906 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ENSVVUP00000017517annotation not available (118 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
ARCActivity-regulated cytoskeleton-associated protein. (396 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (656 aa)
TRIB1Tribbles homolog 1. (141 aa)
LOC112932177Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (971 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
ELK1ETS domain-containing protein Elk-1. (435 aa)
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X3. (1212 aa)
ENSVVUP00000024290annotation not available (257 aa)
ASCL1Achaete-scute homolog 1. (211 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
RPS6KA5Ribosomal protein S6 kinase. (913 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (864 aa)
NAB2NGFI-A-binding protein 2 isoform X1. (525 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (435 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
VRK3Inactive serine/threonine-protein kinase VRK3 isoform X2. (458 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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