STRINGSTRING
PIK3CB PIK3CB LOC112911890 LOC112911890 SPNS3 SPNS3 PSMB6 PSMB6 TRBV30 TRBV30 ENSVVUP00000038751 ENSVVUP00000038751 ENSVVUP00000038760 ENSVVUP00000038760 ENSVVUP00000038761 ENSVVUP00000038761 TRBV25-1 TRBV25-1 ENSVVUP00000038765 ENSVVUP00000038765 ENSVVUP00000038768 ENSVVUP00000038768 ENSVVUP00000038772 ENSVVUP00000038772 ENSVVUP00000038773 ENSVVUP00000038773 ENSVVUP00000038776 ENSVVUP00000038776 PSME2 PSME2 PLCG1 PLCG1 ENSVVUP00000041103 ENSVVUP00000041103 IKBKG IKBKG PSMA3 PSMA3 PTPRC PTPRC PSMC6 PSMC6 BCL10 BCL10 ENSVVUP00000038789 ENSVVUP00000038789 ENSVVUP00000038791 ENSVVUP00000038791 ENSVVUP00000040094 ENSVVUP00000040094 LOC112915328 LOC112915328 PSME1 PSME1 ENSVVUP00000038779 ENSVVUP00000038779 ENSVVUP00000038781 ENSVVUP00000038781 ENSVVUP00000038785 ENSVVUP00000038785 ENSVVUP00000038788 ENSVVUP00000038788 IKBKB IKBKB PSMB2 PSMB2 PAG1 PAG1 PSMD3 PSMD3 LOC112912664 LOC112912664 LOC112912663 LOC112912663 PTEN PTEN RIPK2 RIPK2 PSMA8 PSMA8 PSMB3 PSMB3 ENSVVUP00000003182 ENSVVUP00000003182 FYB1 FYB1 PSMA5 PSMA5 FBXW11 FBXW11 LCP2 LCP2 ENSVVUP00000005276 ENSVVUP00000005276 LOC112923316 LOC112923316 ENSVVUP00000005490 ENSVVUP00000005490 ITK ITK PIK3CA PIK3CA LOC112919437 LOC112919437 TAB2 TAB2 LOC112912331 LOC112912331 CARD11 CARD11 PSMC4 PSMC4 NCK1 NCK1 PSMC5 PSMC5 LOC112921655 LOC112921655 PSMD12 PSMD12 PIK3R1 PIK3R1 PSMA2 PSMA2 PRKCQ PRKCQ PSMB1 PSMB1 TRAF6 TRAF6 LOC112928967 LOC112928967 ENSVVUP00000009448 ENSVVUP00000009448 GRAP2 GRAP2 PTPN22 PTPN22 ENSVVUP00000010304 ENSVVUP00000010304 PSME4 PSME4 PSMA4 PSMA4 UBA52 UBA52 PSMF1 PSMF1 PAK2 PAK2 PDPK1 PDPK1 NFKB1 NFKB1 ENSVVUP00000012574 ENSVVUP00000012574 PIK3R2 PIK3R2 PSMB7 PSMB7 RPS27A RPS27A PSMD10 PSMD10 CD101 CD101 ENSVVUP00000014607 ENSVVUP00000014607 PAK3 PAK3 ENSVVUP00000014764 ENSVVUP00000014764 CD4 CD4 ENSVVUP00000016245 ENSVVUP00000016245 PSMD5 PSMD5 PSMD2 PSMD2 PSMB10 PSMB10 PSMD4 PSMD4 PSMB4 PSMB4 ENSVVUP00000017628 ENSVVUP00000017628 PSMD8 PSMD8 LOC112932868 LOC112932868 MAP3K20-2 MAP3K20-2 MAP3K20 MAP3K20 MAP3K7 MAP3K7 PSMC2 PSMC2 PSMD6 PSMD6 LCK LCK MALT1 MALT1 PSMA7 PSMA7 CUL1 CUL1 PSMD13 PSMD13 ENSVVUP00000023416 ENSVVUP00000023416 PSMD7 PSMD7 ENSVVUP00000023942 ENSVVUP00000023942 WAS WAS ENSVVUP00000024657 ENSVVUP00000024657 PSMC1 PSMC1 CSK CSK PSMD14 PSMD14 ENSVVUP00000026875 ENSVVUP00000026875 ENSVVUP00000026908 ENSVVUP00000026908 PSMB5 PSMB5 PSMB11 PSMB11 PSMA6 PSMA6 NFKBIA NFKBIA ENSVVUP00000027292 ENSVVUP00000027292 ENSVVUP00000027737 ENSVVUP00000027737 PSMD11 PSMD11 SKP1 SKP1 ENSVVUP00000029975 ENSVVUP00000029975 TRAT1 TRAT1 ENSVVUP00000030237 ENSVVUP00000030237 UBE2V1 UBE2V1 CDC34 CDC34 PTPRJ PTPRJ PSMC3 PSMC3 PAK1 PAK1 PSME3 PSME3 LAT LAT SPNS1 SPNS1 ENSVVUP00000033526 ENSVVUP00000033526 CD3G CD3G CD3D CD3D CD3E CD3E LOC112910913 LOC112910913 ENSVVUP00000033877 ENSVVUP00000033877 ENSVVUP00000034029 ENSVVUP00000034029 TRAV29DV5 TRAV29DV5 TRAV23DV6 TRAV23DV6 ENSVVUP00000034044 ENSVVUP00000034044 ENSVVUP00000034049 ENSVVUP00000034049 CHUK CHUK HLA-DRA HLA-DRA LOC112913648 LOC112913648 LOC112913861 LOC112913861 PSMB8 PSMB8 PSMB9 PSMB9 HLA-DPA1 HLA-DPA1 ENSVVUP00000034968 ENSVVUP00000034968 INPP5D INPP5D ENSVVUP00000035544 ENSVVUP00000035544 PSMD1 PSMD1 UBC UBC ENSVVUP00000036620 ENSVVUP00000036620 CD247 CD247 RELA RELA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC112911890Phosphoinositide phospholipase C. (1064 aa)
SPNS3Protein spinster homolog 3. (587 aa)
PSMB6Proteasome subunit beta. (239 aa)
TRBV30T cell receptor beta variable 30 (gene/pseudogene). (148 aa)
ENSVVUP00000038751annotation not available (284 aa)
ENSVVUP00000038760annotation not available (113 aa)
ENSVVUP00000038761annotation not available (113 aa)
TRBV25-1T cell receptor beta variable 25-1. (122 aa)
ENSVVUP00000038765annotation not available (146 aa)
ENSVVUP00000038768annotation not available (174 aa)
ENSVVUP00000038772annotation not available (146 aa)
ENSVVUP00000038773annotation not available (136 aa)
ENSVVUP00000038776annotation not available (200 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1256 aa)
ENSVVUP00000041103annotation not available (105 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (419 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X2. (1153 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
BCL10B-cell lymphoma/leukemia 10. (235 aa)
ENSVVUP00000038789annotation not available (129 aa)
ENSVVUP00000038791annotation not available (145 aa)
ENSVVUP00000040094annotation not available (128 aa)
LOC112915328Tyrosine-protein kinase. (221 aa)
PSME1Proteasome activator complex subunit 1. (279 aa)
ENSVVUP00000038779annotation not available (159 aa)
ENSVVUP00000038781annotation not available (156 aa)
ENSVVUP00000038785annotation not available (133 aa)
ENSVVUP00000038788annotation not available (135 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (782 aa)
PSMB2Proteasome subunit beta. (189 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (433 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
LOC112912664SLA class II histocompatibility antigen, DQ haplotype C beta chain-like. (313 aa)
LOC112912663HLA class II histocompatibility antigen, DQ alpha 2 chain-like; Belongs to the MHC class II family. (255 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (369 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
PSMA8Proteasome endopeptidase complex. (405 aa)
PSMB3Proteasome subunit beta. (196 aa)
ENSVVUP00000003182annotation not available (261 aa)
FYB1FYN-binding protein 1. (821 aa)
PSMA5Proteasome subunit alpha type. (264 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X2. (593 aa)
LCP2Lymphocyte cytosolic protein 2. (530 aa)
ENSVVUP00000005276annotation not available (161 aa)
LOC112923316Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
ENSVVUP00000005490annotation not available (72 aa)
ITKTyrosine-protein kinase. (625 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC112919437Proteasome subunit alpha type-1-like. (265 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
LOC112912331Phosphoinositide phospholipase C. (690 aa)
CARD11Caspase recruitment domain-containing protein 11. (1147 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
NCK1Cytoplasmic protein. (377 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
LOC112921655Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X1. (456 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (463 aa)
PSMB1Proteasome subunit beta. (294 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC112928967Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSVVUP00000009448annotation not available (262 aa)
GRAP2GRB2-related adapter protein 2. (386 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22. (759 aa)
ENSVVUP00000010304annotation not available (270 aa)
PSME4Proteasome activator complex subunit 4. (1823 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (418 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (601 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
ENSVVUP00000012574annotation not available (262 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (735 aa)
PSMB7Proteasome subunit beta. (239 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
CD101Immunoglobulin superfamily member 2. (862 aa)
ENSVVUP00000014607annotation not available (200 aa)
PAK3Non-specific serine/threonine protein kinase. (547 aa)
ENSVVUP00000014764annotation not available (139 aa)
CD4T-cell surface glycoprotein CD4. (462 aa)
ENSVVUP00000016245annotation not available (152 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (461 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (410 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
ENSVVUP00000017628annotation not available (263 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (452 aa)
LOC112932868Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
MAP3K20-2Mitogen-activated protein kinase kinase kinase 20 isoform X2. (487 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (509 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
LCKTyrosine-protein kinase. (249 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (795 aa)
PSMA7Proteasome endopeptidase complex. (243 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
ENSVVUP00000023416Ubiquitin-conjugating enzyme E2 N-like. (105 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
ENSVVUP00000023942Ubiquitin-conjugating enzyme E2 N-like. (93 aa)
WASLOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein. (481 aa)
ENSVVUP00000024657annotation not available (103 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
CSKTyrosine-protein kinase. (450 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
ENSVVUP00000026875annotation not available (107 aa)
ENSVVUP00000026908annotation not available (155 aa)
PSMB5Proteasome subunit beta. (277 aa)
PSMB11Proteasome subunit beta. (327 aa)
PSMA6Proteasome subunit alpha type. (228 aa)
NFKBIANF-kappa-B inhibitor alpha. (327 aa)
ENSVVUP00000027292Ubiquitin-conjugating enzyme E2 N-like. (146 aa)
ENSVVUP00000027737annotation not available (222 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (410 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
ENSVVUP00000029975annotation not available (85 aa)
TRAT1T-cell receptor-associated transmembrane adapter 1. (181 aa)
ENSVVUP00000030237annotation not available (144 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1 isoform X3. (105 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (306 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta. (1224 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PSME3Proteasome activator complex subunit 3. (247 aa)
LATLinker for activation of T-cells family member 1. (238 aa)
SPNS1Protein spinster homolog 1. (561 aa)
ENSVVUP00000033526annotation not available (137 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (170 aa)
CD3DT-cell surface glycoprotein CD3 delta chain isoform X2. (180 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (198 aa)
LOC112910913Ubiquitin-like. (77 aa)
ENSVVUP00000033877annotation not available (238 aa)
ENSVVUP00000034029annotation not available (121 aa)
TRAV29DV5T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene). (155 aa)
TRAV23DV6T cell receptor alpha variable 23/delta variable 6. (132 aa)
ENSVVUP00000034044annotation not available (129 aa)
ENSVVUP00000034049annotation not available (128 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
HLA-DRAHLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (265 aa)
LOC112913648DLA class II histocompatibility antigen, DR-1 beta chain. (287 aa)
LOC112913861SLA class II histocompatibility antigen, DQ haplotype C beta chain-like. (269 aa)
PSMB8Proteasome subunit beta. (306 aa)
PSMB9Proteasome subunit beta. (209 aa)
HLA-DPA1LOW QUALITY PROTEIN: RLA class II histocompatibility antigen, DP alpha-1 chain-like; Belongs to the MHC class II family. (249 aa)
ENSVVUP00000034968annotation not available (145 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
ENSVVUP00000035544annotation not available (382 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1037 aa)
UBCpolyubiquitin-C. (190 aa)
ENSVVUP00000036620annotation not available (157 aa)
CD247CD247 molecule. (176 aa)
RELATranscription factor p65 isoform X2. (542 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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