STRINGSTRING
PRKCG PRKCG WNT4 WNT4 PSMC6 PSMC6 PSMA3 PSMA3 DAAM1 DAAM1 ENSVVUP00000041103 ENSVVUP00000041103 PSME2 PSME2 PSME1 PSME1 ENSVVUP00000040094 ENSVVUP00000040094 DVL2 DVL2 ARRB2 ARRB2 PSMB6 PSMB6 LOC112924987 LOC112924987 PFN1 PFN1 PRICKLE4 PRICKLE4 DAAM2 DAAM2 ENSVVUP00000036620 ENSVVUP00000036620 UBC UBC PSMD1 PSMD1 ENSVVUP00000035544 ENSVVUP00000035544 PSMB9 PSMB9 PSMB8 PSMB8 FHDC1 FHDC1 ENSVVUP00000033877 ENSVVUP00000033877 LOC112910913 LOC112910913 WNT11 WNT11 ENSVVUP00000033527 ENSVVUP00000033527 ENSVVUP00000033526 ENSVVUP00000033526 PSME3 PSME3 RAC2 RAC2 PSMC3 PSMC3 ENSVVUP00000030618 ENSVVUP00000030618 ROR2 ROR2 ENSVVUP00000030237 ENSVVUP00000030237 ENSVVUP00000029975 ENSVVUP00000029975 AP2A1 AP2A1 ENSVVUP00000029104 ENSVVUP00000029104 WNT5A WNT5A PSMD11 PSMD11 AP2B1 AP2B1 WNT5B WNT5B ENSVVUP00000027737 ENSVVUP00000027737 CLTA CLTA PSMA6 PSMA6 PSMB11 PSMB11 PSMB5 PSMB5 ENSVVUP00000026875 ENSVVUP00000026875 WNT1 WNT1 FZD4 FZD4 PSMD14 PSMD14 FZD7 FZD7 PSMC1 PSMC1 ENSVVUP00000024677 ENSVVUP00000024677 FZD2 FZD2 PRICKLE3 PRICKLE3 CLTC CLTC PSMD7 PSMD7 FZD6 FZD6 PRICKLE1 PRICKLE1 PSMD13 PSMD13 PSMA7 PSMA7 RAC1 RAC1 ENSVVUP00000020892 ENSVVUP00000020892 PSMD6 PSMD6 PRICKLE2 PRICKLE2 PSMC2 PSMC2 ROR1 ROR1 FZD1 FZD1 PSMD8 PSMD8 ENSVVUP00000017628 ENSVVUP00000017628 PSMB4 PSMB4 PSMD4 PSMD4 PSMB10 PSMB10 PARD6A PARD6A PSMD2 PSMD2 ENSVVUP00000016277 ENSVVUP00000016277 PSMD5 PSMD5 ENSVVUP00000016245 ENSVVUP00000016245 FZD5 FZD5 SMURF1 SMURF1 ENSVVUP00000014764 ENSVVUP00000014764 ENSVVUP00000014607 ENSVVUP00000014607 AP2M1-2 AP2M1-2 PSMD10 PSMD10 RPS27A RPS27A PSMB7 PSMB7 ENSVVUP00000012574 ENSVVUP00000012574 PSMF1 PSMF1 UBA52 UBA52 PSMA4 PSMA4 PSME4 PSME4 ENSVVUP00000010304 ENSVVUP00000010304 AP2M1 AP2M1 DVL3 DVL3 ENSVVUP00000009448 ENSVVUP00000009448 PSMB1 PSMB1 PRKCA PRKCA PSMA2 PSMA2 PSMD12 PSMD12 SMURF2 SMURF2 PSMC5 PSMC5 PSMC4 PSMC4 PRKCB PRKCB LOC112919437 LOC112919437 DVL1 DVL1 LOC112923316 LOC112923316 FZD3 FZD3 PSMA5 PSMA5 ENSVVUP00000003182 ENSVVUP00000003182 PSMB3 PSMB3 PSMA8 PSMA8 CLTB CLTB PSMD3 PSMD3 RAC3 RAC3 FZD8 FZD8 PSMB2 PSMB2 AP2A2 AP2A2 AP2S1 AP2S1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
DAAM1Disheveled-associated activator of morphogenesis 1 isoform X2. (1068 aa)
ENSVVUP00000041103annotation not available (105 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSME1Proteasome activator complex subunit 1. (279 aa)
ENSVVUP00000040094annotation not available (128 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X4. (732 aa)
ARRB2Beta-arrestin-2 isoform X1. (409 aa)
PSMB6Proteasome subunit beta. (239 aa)
LOC112924987Profilin; Belongs to the profilin family. (384 aa)
PFN1LOW QUALITY PROTEIN: profilin-1. (72 aa)
PRICKLE4Prickle planar cell polarity protein 4. (539 aa)
DAAM2Disheveled-associated activator of morphogenesis 2 isoform X1. (1114 aa)
ENSVVUP00000036620annotation not available (157 aa)
UBCpolyubiquitin-C. (190 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1037 aa)
ENSVVUP00000035544annotation not available (382 aa)
PSMB9Proteasome subunit beta. (209 aa)
PSMB8Proteasome subunit beta. (306 aa)
FHDC1FH2 domain-containing protein 1. (992 aa)
ENSVVUP00000033877annotation not available (238 aa)
LOC112910913Ubiquitin-like. (77 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSVVUP00000033527annotation not available (166 aa)
ENSVVUP00000033526annotation not available (137 aa)
PSME3Proteasome activator complex subunit 3. (247 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (173 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
ENSVVUP00000030618annotation not available (170 aa)
ROR2Tyrosine-protein kinase transmembrane receptor ROR2 isoform X2. (682 aa)
ENSVVUP00000030237annotation not available (144 aa)
ENSVVUP00000029975annotation not available (85 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
ENSVVUP00000029104annotation not available (140 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (410 aa)
AP2B1AP complex subunit beta. (958 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (440 aa)
ENSVVUP00000027737annotation not available (222 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
PSMA6Proteasome subunit alpha type. (228 aa)
PSMB11Proteasome subunit beta. (327 aa)
PSMB5Proteasome subunit beta. (277 aa)
ENSVVUP00000026875annotation not available (107 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (505 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
ENSVVUP00000024677annotation not available (111 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
PRICKLE3Prickle planar cell polarity protein 3 isoform X2. (617 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1536 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
PRICKLE1Prickle-like protein 1. (832 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMA7Proteasome endopeptidase complex. (243 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (202 aa)
ENSVVUP00000020892annotation not available (122 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
PRICKLE2Prickle-like protein 2 isoform X1. (823 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (874 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (452 aa)
ENSVVUP00000017628annotation not available (263 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (410 aa)
PSMB10Proteasome subunit beta. (273 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (513 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSVVUP00000016277annotation not available (152 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (461 aa)
ENSVVUP00000016245annotation not available (152 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
SMURF1E3 ubiquitin-protein ligase. (756 aa)
ENSVVUP00000014764annotation not available (139 aa)
ENSVVUP00000014607annotation not available (200 aa)
AP2M1-2AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (435 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMB7Proteasome subunit beta. (239 aa)
ENSVVUP00000012574annotation not available (262 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (418 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME4Proteasome activator complex subunit 4. (1823 aa)
ENSVVUP00000010304annotation not available (270 aa)
AP2M1AP-2 complex subunit mu-1. (357 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X2. (747 aa)
ENSVVUP00000009448annotation not available (262 aa)
PSMB1Proteasome subunit beta. (294 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X1. (456 aa)
SMURF2E3 ubiquitin-protein ligase. (779 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC112919437Proteasome subunit alpha type-1-like. (265 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
LOC112923316Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PSMA5Proteasome subunit alpha type. (264 aa)
ENSVVUP00000003182annotation not available (261 aa)
PSMB3Proteasome subunit beta. (196 aa)
PSMA8Proteasome endopeptidase complex. (405 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (204 aa)
FZD8LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (632 aa)
PSMB2Proteasome subunit beta. (189 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (935 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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