STRINGSTRING
IL17F IL17F FOSL2 FOSL2 RIPK2 RIPK2 MAPKAPK2 MAPKAPK2 IL17C IL17C ENSVVUP00000005393 ENSVVUP00000005393 TAB2 TAB2 FOS FOS ENSVVUP00000007999 ENSVVUP00000007999 LOC112921655 LOC112921655 TRAF6 TRAF6 LOC112928967 LOC112928967 TAB3 TAB3 UBA52 UBA52 MAP2K6 MAP2K6 RPS27A RPS27A ENSVVUP00000014764 ENSVVUP00000014764 PPP2R1A PPP2R1A DUSP6 DUSP6 ENSVVUP00000016091 ENSVVUP00000016091 PPP4R1 PPP4R1 CREB1 CREB1 RPS6KA1 RPS6KA1 ATF2 ATF2 ENSVVUP00000017517 ENSVVUP00000017517 RPS6KA3 RPS6KA3 LOC112932868 LOC112932868 MAPK10 MAPK10 MAP3K20-2 MAP3K20-2 MAP3K20 MAP3K20 MAP3K7 MAP3K7 TAB1 TAB1 PPP2R1B PPP2R1B LOC112932177 LOC112932177 ENSVVUP00000023416 ENSVVUP00000023416 DUSP3 DUSP3 ELK1 ELK1 ENSVVUP00000023942 ENSVVUP00000023942 RELCH RELCH ENSVVUP00000024290 ENSVVUP00000024290 ENSVVUP00000024657 ENSVVUP00000024657 RPS6KA5 RPS6KA5 PPP4R4 PPP4R4 NOD2 NOD2 DUSP4 DUSP4 PPP2CB PPP2CB IL25 IL25 ENSVVUP00000027292 ENSVVUP00000027292 VRK3 VRK3 MAPK1 MAPK1 IL17RB IL17RB MAPK8 MAPK8 NOD1 NOD1 PPP2CA PPP2CA ENSVVUP00000029422 ENSVVUP00000029422 RPS6KA2 RPS6KA2 IL17RA IL17RA UBE2V1 UBE2V1 LOC112917600 LOC112917600 MAPK15 MAPK15 FNBP4 FNBP4 IRAK2 IRAK2 IL17RC IL17RC IL17RE IL17RE TNIP2 TNIP2 LOC112910913 LOC112910913 CREB5 CREB5 MAPK11 MAPK11 UBC UBC ATF1 ATF1 MAPK3 MAPK3 MAPK14 MAPK14 ENSVVUP00000037430 ENSVVUP00000037430 DUSP7 DUSP7 MAPK9 MAPK9 MAP2K7 MAP2K7 PPP2R5D PPP2R5D ATF7 ATF7 MAPKAPK3 MAPKAPK3 ENSVVUP00000040094 ENSVVUP00000040094 IL17A IL17A IKBKG IKBKG IRAK1 IRAK1 RPS6KA4 RPS6KA4 MAP2K4 MAP2K4 MAPK7 MAPK7 MAP2K3 MAP2K3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL17Finterleukin-17F. (196 aa)
FOSL2Fos-related antigen 2. (325 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (429 aa)
IL17CInterleukin 17C. (202 aa)
ENSVVUP00000005393annotation not available (155 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
FOSProto-oncogene c-Fos. (380 aa)
ENSVVUP00000007999annotation not available (96 aa)
LOC112921655Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LOC112928967Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1. (717 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
ENSVVUP00000014764annotation not available (139 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
ENSVVUP00000016091annotation not available (109 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (906 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
ENSVVUP00000017517annotation not available (118 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
LOC112932868Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
MAPK10Mitogen-activated protein kinase. (529 aa)
MAP3K20-2Mitogen-activated protein kinase kinase kinase 20 isoform X2. (487 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (509 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (656 aa)
LOC112932177Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (971 aa)
ENSVVUP00000023416Ubiquitin-conjugating enzyme E2 N-like. (105 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
ELK1ETS domain-containing protein Elk-1. (435 aa)
ENSVVUP00000023942Ubiquitin-conjugating enzyme E2 N-like. (93 aa)
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X3. (1212 aa)
ENSVVUP00000024290annotation not available (257 aa)
ENSVVUP00000024657annotation not available (103 aa)
RPS6KA5Ribosomal protein S6 kinase. (913 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (864 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1043 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (435 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
IL25Interleukin-25. (160 aa)
ENSVVUP00000027292Ubiquitin-conjugating enzyme E2 N-like. (146 aa)
VRK3Inactive serine/threonine-protein kinase VRK3 isoform X2. (458 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
IL17RBInterleukin-17 receptor B isoform X1. (501 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ENSVVUP00000029422Ubiquitin-conjugating enzyme E2 N-like. (89 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
IL17RAInterleukin-17 receptor A. (746 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1 isoform X3. (105 aa)
LOC112917600Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
MAPK15Mitogen-activated protein kinase. (601 aa)
FNBP4LOW QUALITY PROTEIN: formin-binding protein 4. (1022 aa)
IRAK2Interleukin-1 receptor-associated kinase-like 2. (598 aa)
IL17RCInterleukin-17 receptor C isoform X1. (716 aa)
IL17REInterleukin-17 receptor E isoform X2. (628 aa)
TNIP2TNFAIP3-interacting protein 2 isoform X1. (435 aa)
LOC112910913Ubiquitin-like. (77 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (548 aa)
MAPK11Mitogen-activated protein kinase. (332 aa)
UBCpolyubiquitin-C. (190 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X2. (270 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSVVUP00000037430annotation not available (99 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (464 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X2. (439 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (604 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (483 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
ENSVVUP00000040094annotation not available (128 aa)
IL17Ainterleukin-17A. (148 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (419 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (551 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (709 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (455 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (397 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.