STRINGSTRING
MAPK3 MAPK3 RPS6KA2 RPS6KA2 PPP2CA PPP2CA MAPK8 MAPK8 MAPK1 MAPK1 VRK3 VRK3 PPP2CB PPP2CB DUSP4 DUSP4 PPP4R4 PPP4R4 RPS6KA5 RPS6KA5 ENSVVUP00000024290 ENSVVUP00000024290 RELCH RELCH ELK1 ELK1 DUSP3 DUSP3 LOC112932177 LOC112932177 PPP2R1B PPP2R1B MAPK10 MAPK10 RPS6KA3 RPS6KA3 ENSVVUP00000017517 ENSVVUP00000017517 ATF2 ATF2 RPS6KA1 RPS6KA1 CREB1 CREB1 PPP4R1 PPP4R1 DUSP6 DUSP6 PPP2R1A PPP2R1A FOS FOS ENSVVUP00000005393 ENSVVUP00000005393 MAPKAPK2 MAPKAPK2 FOSL2 FOSL2 MAPK7 MAPK7 RPS6KA4 RPS6KA4 ATF7 ATF7 PPP2R5D PPP2R5D MAPK9 MAPK9 DUSP7 DUSP7 MAPK14 MAPK14 ATF1 ATF1 MAPK11 MAPK11 CREB5 CREB5 FNBP4 FNBP4 MAPK15 MAPK15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
VRK3Inactive serine/threonine-protein kinase VRK3 isoform X2. (458 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (435 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (864 aa)
RPS6KA5Ribosomal protein S6 kinase. (913 aa)
ENSVVUP00000024290annotation not available (257 aa)
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X3. (1212 aa)
ELK1ETS domain-containing protein Elk-1. (435 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
LOC112932177Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (971 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (656 aa)
MAPK10Mitogen-activated protein kinase. (529 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
ENSVVUP00000017517annotation not available (118 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (906 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
FOSProto-oncogene c-Fos. (380 aa)
ENSVVUP00000005393annotation not available (155 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (429 aa)
FOSL2Fos-related antigen 2. (325 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (709 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (483 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (604 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (464 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X2. (270 aa)
MAPK11Mitogen-activated protein kinase. (332 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (548 aa)
FNBP4LOW QUALITY PROTEIN: formin-binding protein 4. (1022 aa)
MAPK15Mitogen-activated protein kinase. (601 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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