STRINGSTRING
RAF1 RAF1 FCER1G FCER1G MALT1 MALT1 PSMA7 PSMA7 CREBBP CREBBP CUL1 CUL1 PSMD13 PSMD13 ENSVVUP00000023416 ENSVVUP00000023416 HRAS HRAS NFAT5 NFAT5 PSMD7 PSMD7 ENSVVUP00000023942 ENSVVUP00000023942 LYN LYN ENSVVUP00000024657 ENSVVUP00000024657 PSMC1 PSMC1 CALM1 CALM1 RPS6KA5 RPS6KA5 MAP3K14 MAP3K14 PSMD14 PSMD14 NFATC1 NFATC1 CASP8 CASP8 PPP3R2 PPP3R2 ENSVVUP00000026330 ENSVVUP00000026330 ENSVVUP00000026875 ENSVVUP00000026875 PSMB5 PSMB5 PSMB11 PSMB11 PSMA6 PSMA6 NFKBIA NFKBIA ENSVVUP00000027292 ENSVVUP00000027292 ENSVVUP00000027737 ENSVVUP00000027737 PSMD11 PSMD11 SKP1 SKP1 ENSVVUP00000029975 ENSVVUP00000029975 ENSVVUP00000030237 ENSVVUP00000030237 SYK SYK UBE2V1 UBE2V1 CDC34 CDC34 PSMB10 PSMB10 PSMD2 PSMD2 ENSVVUP00000016277 ENSVVUP00000016277 PSMD5 PSMD5 ENSVVUP00000016245 ENSVVUP00000016245 ENSVVUP00000014764 ENSVVUP00000014764 PAK3 PAK3 ENSVVUP00000014607 ENSVVUP00000014607 CLEC4E CLEC4E CLEC4D CLEC4D PSMD10 PSMD10 RPS27A RPS27A NRAS NRAS PSMB7 PSMB7 ENSVVUP00000012574 ENSVVUP00000012574 NFKB1 NFKB1 PPP3CA PPP3CA PDPK1 PDPK1 PAK2 PAK2 RELB RELB PSMF1 PSMF1 UBA52 UBA52 PSMA4 PSMA4 PSME4 PSME4 TAB3 TAB3 ENSVVUP00000010304 ENSVVUP00000010304 ENSVVUP00000009448 ENSVVUP00000009448 LOC112928967 LOC112928967 TRAF6 TRAF6 PSMB1 PSMB1 EP300 EP300 FYN FYN PSMA2 PSMA2 PSMD12 PSMD12 LOC112921655 LOC112921655 PSMC5 PSMC5 PSMC4 PSMC4 CARD11 CARD11 LOC112912331 LOC112912331 CLEC7A CLEC7A TAB2 TAB2 LOC112919437 LOC112919437 ENSVVUP00000005911 ENSVVUP00000005911 ENSVVUP00000005490 ENSVVUP00000005490 LOC112923316 LOC112923316 ENSVVUP00000005276 ENSVVUP00000005276 NFKB2 NFKB2 UBE2M UBE2M CALM3 CALM3 FBXW11 FBXW11 PSMA5 PSMA5 ENSVVUP00000003182 ENSVVUP00000003182 PSMB3 PSMB3 PSMA8 PSMA8 PSMD3 PSMD3 BTRC BTRC PSMB2 PSMB2 IKBKB IKBKB NFATC2 NFATC2 PPP3CB PPP3CB PSMC3 PSMC3 PAK1 PAK1 PRKCD PRKCD PSME3 PSME3 ENSVVUP00000033526 ENSVVUP00000033526 ENSVVUP00000033527 ENSVVUP00000033527 LOC112910913 LOC112910913 ENSVVUP00000033877 ENSVVUP00000033877 CHUK CHUK PSMB8 PSMB8 PSMB9 PSMB9 ENSVVUP00000035544 ENSVVUP00000035544 PSMD1 PSMD1 UBC UBC ENSVVUP00000036620 ENSVVUP00000036620 PRKACA PRKACA LOC112909736 LOC112909736 RELA RELA LOC112911890 LOC112911890 CARD9 CARD9 PSMB6 PSMB6 WDR92 WDR92 PPP3R1 PPP3R1 PYCARD PYCARD ENSVVUP00000040094 ENSVVUP00000040094 IL1B IL1B PSME1 PSME1 PSME2 PSME2 ENSVVUP00000041103 ENSVVUP00000041103 SRC SRC IKBKG IKBKG PSMA3 PSMA3 PSMC6 PSMC6 RPS6KA4 RPS6KA4 MAP4 MAP4 PRKACB PRKACB BCL10 BCL10 KRAS KRAS PSMD4 PSMD4 NFATC3 NFATC3 PSMB4 PSMB4 ENSVVUP00000017628 ENSVVUP00000017628 PSMD8 PSMD8 LOC112932868 LOC112932868 MAP3K20-2 MAP3K20-2 MAP3K20 MAP3K20 MAP3K7 MAP3K7 UBA3 UBA3 TAB1 TAB1 PSMC2 PSMC2 PSMD6 PSMD6 SRMS SRMS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (90 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (795 aa)
PSMA7Proteasome endopeptidase complex. (243 aa)
CREBBPCREB-binding protein isoform X1. (2442 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
ENSVVUP00000023416Ubiquitin-conjugating enzyme E2 N-like. (105 aa)
HRASGTPase HRas isoform X1. (189 aa)
NFAT5Nuclear factor of activated T-cells 5 isoform X1. (1702 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
ENSVVUP00000023942Ubiquitin-conjugating enzyme E2 N-like. (93 aa)
LYNTyrosine-protein kinase. (512 aa)
ENSVVUP00000024657annotation not available (103 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
CALM1Calmodulin 1. (149 aa)
RPS6KA5Ribosomal protein S6 kinase. (913 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (1045 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (1004 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (397 aa)
PPP3R2Calcineurin subunit B type 2. (252 aa)
ENSVVUP00000026330annotation not available (221 aa)
ENSVVUP00000026875annotation not available (107 aa)
PSMB5Proteasome subunit beta. (277 aa)
PSMB11Proteasome subunit beta. (327 aa)
PSMA6Proteasome subunit alpha type. (228 aa)
NFKBIANF-kappa-B inhibitor alpha. (327 aa)
ENSVVUP00000027292Ubiquitin-conjugating enzyme E2 N-like. (146 aa)
ENSVVUP00000027737annotation not available (222 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (410 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
ENSVVUP00000029975annotation not available (85 aa)
ENSVVUP00000030237annotation not available (144 aa)
SYKTyrosine-protein kinase. (610 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1 isoform X3. (105 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (306 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSVVUP00000016277annotation not available (152 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (461 aa)
ENSVVUP00000016245annotation not available (152 aa)
ENSVVUP00000014764annotation not available (139 aa)
PAK3Non-specific serine/threonine protein kinase. (547 aa)
ENSVVUP00000014607annotation not available (200 aa)
CLEC4EC-type lectin domain family 4 member E-like. (259 aa)
CLEC4DC-type lectin domain family 4 member D-like isoform X1. (212 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
NRASGTPase NRas. (189 aa)
PSMB7Proteasome subunit beta. (239 aa)
ENSVVUP00000012574annotation not available (262 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
PPP3CASerine/threonine-protein phosphatase. (572 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (601 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
RELBTranscription factor RelB. (574 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (418 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME4Proteasome activator complex subunit 4. (1823 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1. (717 aa)
ENSVVUP00000010304annotation not available (270 aa)
ENSVVUP00000009448annotation not available (262 aa)
LOC112928967Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
PSMB1Proteasome subunit beta. (294 aa)
EP300Histone acetyltransferase p300 isoform X1. (2430 aa)
FYNTyrosine-protein kinase. (537 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X1. (456 aa)
LOC112921655Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
CARD11Caspase recruitment domain-containing protein 11. (1147 aa)
LOC112912331Phosphoinositide phospholipase C. (690 aa)
CLEC7AC-type lectin domain family 7 member A isoform X2. (246 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
LOC112919437Proteasome subunit alpha type-1-like. (265 aa)
ENSVVUP00000005911annotation not available (91 aa)
ENSVVUP00000005490annotation not available (72 aa)
LOC112923316Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
ENSVVUP00000005276annotation not available (161 aa)
NFKB2LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p100 subunit. (863 aa)
UBE2MNEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
CALM3Calmodulin-1; Belongs to the calmodulin family. (149 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X2. (593 aa)
PSMA5Proteasome subunit alpha type. (264 aa)
ENSVVUP00000003182annotation not available (261 aa)
PSMB3Proteasome subunit beta. (196 aa)
PSMA8Proteasome endopeptidase complex. (405 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
PSMB2Proteasome subunit beta. (189 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (782 aa)
NFATC2LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 2. (902 aa)
PPP3CBSerine/threonine-protein phosphatase. (529 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
PSME3Proteasome activator complex subunit 3. (247 aa)
ENSVVUP00000033526annotation not available (137 aa)
ENSVVUP00000033527annotation not available (166 aa)
LOC112910913Ubiquitin-like. (77 aa)
ENSVVUP00000033877annotation not available (238 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
PSMB8Proteasome subunit beta. (306 aa)
PSMB9Proteasome subunit beta. (209 aa)
ENSVVUP00000035544annotation not available (382 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1037 aa)
UBCpolyubiquitin-C. (190 aa)
ENSVVUP00000036620annotation not available (157 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
LOC112909736CD209 antigen-like protein 2 isoform X1. (249 aa)
RELATranscription factor p65 isoform X2. (542 aa)
LOC112911890Phosphoinositide phospholipase C. (1064 aa)
CARD9Caspase recruitment domain-containing protein 9. (520 aa)
PSMB6Proteasome subunit beta. (239 aa)
WDR92WD repeat-containing protein 92. (357 aa)
PPP3R1Calcineurin subunit B type 1. (192 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD isoform X1. (195 aa)
ENSVVUP00000040094annotation not available (128 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa)
PSME1Proteasome activator complex subunit 1. (279 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
ENSVVUP00000041103annotation not available (105 aa)
SRCTyrosine-protein kinase. (536 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (419 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (709 aa)
MAP4Microtubule-associated protein. (1213 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
BCL10B-cell lymphoma/leukemia 10. (235 aa)
KRASGTPase KRas isoform X1. (418 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (410 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1074 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
ENSVVUP00000017628annotation not available (263 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (452 aa)
LOC112932868Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
MAP3K20-2Mitogen-activated protein kinase kinase kinase 20 isoform X2. (487 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (509 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
UBA3NEDD8-activating enzyme E1 catalytic subunit isoform X1. (455 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
SRMSTyrosine-protein kinase. (885 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (18%) [HD]