STRINGSTRING
GPS1 GPS1 PARP1 PARP1 COPS8 COPS8 WBP1 WBP1 INO80B INO80B ACTL6A ACTL6A DDB1 DDB1 LOC112912370 LOC112912370 ACTB ACTB ENSVVUP00000008444 ENSVVUP00000008444 RBX1 RBX1 VWA5B2 VWA5B2 UBA52 UBA52 TFPT TFPT PARP2 PARP2 RPS27A RPS27A WDR76 WDR76 ENSVVUP00000014764 ENSVVUP00000014764 COPS7A COPS7A ENSVVUP00000018607 ENSVVUP00000018607 ENSVVUP00000019178 ENSVVUP00000019178 COPS4 COPS4 COPS2 COPS2 INO80D INO80D RPAP3 RPAP3 XPC XPC RUVBL1 RUVBL1 COPS5 COPS5 CUL4A CUL4A ACTG1 ACTG1 NFRKB NFRKB ENSVVUP00000027397 ENSVVUP00000027397 VWA5A VWA5A ACTR8 ACTR8 MCRS1 MCRS1 ENSVVUP00000028823 ENSVVUP00000028823 CETN3 CETN3 COPS6 COPS6 RAD23A RAD23A LOC112910913 LOC112910913 COPS7B COPS7B UBC UBC ENSVVUP00000036012 ENSVVUP00000036012 INO80E INO80E DDB2 DDB2 INO80 INO80 PARP3 PARP3 RAD23B RAD23B INO80C INO80C CUL4B CUL4B YY1 YY1 ENSVVUP00000040094 ENSVVUP00000040094 ACTR5 ACTR5 VWA5B1 VWA5B1 COPS3 COPS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPS1COP9 signalosome complex subunit 1 isoform X1. (750 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (972 aa)
COPS8COP9 signalosome complex subunit 8. (212 aa)
WBP1WW domain-binding protein 1 isoform X1. (301 aa)
INO80BINO80 complex subunit B. (356 aa)
ACTL6AActin-like protein 6A isoform X1; Belongs to the actin family. (447 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
LOC112912370Centrin-2. (168 aa)
ACTBActin beta. (276 aa)
ENSVVUP00000008444annotation not available (146 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa)
VWA5B2Von Willebrand factor A domain-containing protein 5B2 isoform X2. (1224 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
TFPTTCF3 fusion partner isoform X1. (253 aa)
PARP2Poly [ADP-ribose] polymerase. (563 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (759 aa)
ENSVVUP00000014764annotation not available (139 aa)
COPS7ACOP9 signalosome complex subunit 7a isoform X2. (304 aa)
ENSVVUP00000018607annotation not available (146 aa)
ENSVVUP00000019178annotation not available (108 aa)
COPS4COP9 signalosome complex subunit 4 isoform X1. (406 aa)
COPS2COP9 signalosome complex subunit 2 isoform X2. (413 aa)
INO80DINO80 complex subunit D. (1024 aa)
RPAP3RNA polymerase II-associated protein 3 isoform X1. (663 aa)
XPCDNA repair protein complementing XP-C cells isoform X1. (1023 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
COPS5COP9 signalosome complex subunit 5 isoform X1. (334 aa)
CUL4Acullin-4A; Belongs to the cullin family. (891 aa)
ACTG1LOW QUALITY PROTEIN: actin, cytoplasmic 2. (364 aa)
NFRKBNuclear factor related to kappa-B-binding protein isoform X2. (1299 aa)
ENSVVUP00000027397annotation not available (156 aa)
VWA5AVon Willebrand factor A domain-containing protein 5A isoform X1. (829 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
MCRS1Microspherule protein 1 isoform X1. (518 aa)
ENSVVUP00000028823annotation not available (332 aa)
CETN3Centrin-3. (183 aa)
COPS6LOW QUALITY PROTEIN: COP9 signalosome complex subunit 6. (352 aa)
RAD23AUV excision repair protein RAD23 homolog A isoform X1. (370 aa)
LOC112910913Ubiquitin-like. (77 aa)
COPS7BCOP9 signalosome complex subunit 7b isoform X1. (332 aa)
UBCpolyubiquitin-C. (190 aa)
ENSVVUP00000036012annotation not available (113 aa)
INO80EINO80 complex subunit E. (309 aa)
DDB2DNA damage-binding protein 2 isoform X2. (427 aa)
INO80Chromatin-remodeling ATPase INO80. (1560 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
RAD23BUV excision repair protein RAD23 homolog B. (387 aa)
INO80CINO80 complex subunit C isoform X1. (192 aa)
CUL4Bcullin-4B isoform X2; Belongs to the cullin family. (948 aa)
YY1Transcriptional repressor protein YY1. (408 aa)
ENSVVUP00000040094annotation not available (128 aa)
ACTR5Actin-related protein 5; Belongs to the actin family. (576 aa)
VWA5B1Von Willebrand factor A domain-containing protein 5B1 isoform X1. (1148 aa)
COPS3COP9 signalosome complex subunit 3 isoform X1. (423 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.