63 items (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCNH	LOW QUALITY PROTEIN: cyclin-H; Belongs to the cyclin family. (322 aa)
	CDK2	Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
	UBA52	ubiquitin-60S ribosomal protein L40. (231 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)
	CDK3	Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily. (305 aa)
	TFDP1	Transcription factor. (410 aa)
	PPP4R1	Serine/threonine-protein phosphatase 4 regulatory subunit 1. (906 aa)
	E2F4	Transcription factor E2F4. (412 aa)
	PPP2R1A	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
	ENSVVUP00000014764	annotation not available (139 aa)
	SKP2	S-phase kinase-associated protein 2. (436 aa)
	ENSVVUP00000013849	annotation not available (54 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	PPP2R3B	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1. (569 aa)
	CDKN1A	Cyclin-dependent kinase inhibitor 1. (164 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (327 aa)
	RBL1	Retinoblastoma-like protein 1 isoform X1. (1068 aa)
	SRC	Tyrosine-protein kinase. (536 aa)
	RELCH	lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X3. (1212 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	CCND2	G1/S-specific cyclin-D2; Belongs to the cyclin family. (325 aa)
	CDK7	Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (348 aa)
	CDKN2C	Cyclin-dependent kinase 4 inhibitor C. (168 aa)
	PPP2R3A	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1152 aa)
	E2F1	Transcription factor E2F1. (390 aa)
	CCND1	G1/S-specific cyclin-D1; Belongs to the cyclin family. (386 aa)
	CDKN1B	Cyclin-dependent kinase inhibitor 1B. (198 aa)
	ENSVVUP00000005490	annotation not available (72 aa)
	ENSVVUP00000005419	annotation not available (48 aa)
	ENSVVUP00000005393	annotation not available (155 aa)
	ENSVVUP00000005276	annotation not available (161 aa)
	CDK6	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (463 aa)
	PPP2R1B	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (656 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	CDK4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
	CCNE1	G1/S-specific cyclin-E1; Belongs to the cyclin family. (395 aa)
	LOC112932177	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (971 aa)
	CDKN2D	Cyclin-dependent kinase 4 inhibitor D. (166 aa)
	PPP2R2A	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa)
	CDKN1C	Cyclin-dependent kinase inhibitor 1C. (165 aa)
	CCNE2	G1/S-specific cyclin-E2 isoform X2; Belongs to the cyclin family. (404 aa)
	E2F3	Transcription factor E2F3. (224 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1220 aa)
	E2F5	Transcription factor E2F5. (422 aa)
	SKP1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	PPP2R2B	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (512 aa)
	PPP2R3C	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (279 aa)
	RBL2	Retinoblastoma-like protein 2 isoform X1. (1139 aa)
	PPP4R4	Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (864 aa)
	CCND3	G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (401 aa)
	E2F2	Transcription factor E2F2. (447 aa)
	ABL1	Tyrosine-protein kinase. (1150 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1199 aa)
	RB1	Retinoblastoma-associated protein. (928 aa)
	ENSVVUP00000040094	annotation not available (128 aa)
	TFDP2	Transcription factor. (430 aa)
	UBC	polyubiquitin-C. (190 aa)
	LOC112910913	Ubiquitin-like. (77 aa)
	FNBP4	LOW QUALITY PROTEIN: formin-binding protein 4. (1022 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CCND1	ENSVVUP00000038805	ENSVVUP00000006071	Tyrosine-protein kinase.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.411
ABL1	CDK4	ENSVVUP00000038805	ENSVVUP00000022976	Tyrosine-protein kinase.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.402
ABL1	CDKN1A	ENSVVUP00000038805	ENSVVUP00000036825	Tyrosine-protein kinase.	Cyclin-dependent kinase inhibitor 1.	0.504
ABL1	CUL1	ENSVVUP00000038805	ENSVVUP00000022561	Tyrosine-protein kinase.	Cullin-1; Belongs to the cullin family.	0.424
ABL1	RB1	ENSVVUP00000038805	ENSVVUP00000039731	Tyrosine-protein kinase.	Retinoblastoma-associated protein.	0.950
CCND1	ABL1	ENSVVUP00000006071	ENSVVUP00000038805	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Tyrosine-protein kinase.	0.411
CCND1	CCND2	ENSVVUP00000006071	ENSVVUP00000024652	G1/S-specific cyclin-D1; Belongs to the cyclin family.	G1/S-specific cyclin-D2; Belongs to the cyclin family.	0.937
CCND1	CCND3	ENSVVUP00000006071	ENSVVUP00000037306	G1/S-specific cyclin-D1; Belongs to the cyclin family.	G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family.	0.941
CCND1	CCNE1	ENSVVUP00000006071	ENSVVUP00000023024	G1/S-specific cyclin-D1; Belongs to the cyclin family.	G1/S-specific cyclin-E1; Belongs to the cyclin family.	0.709
CCND1	CCNE2	ENSVVUP00000006071	ENSVVUP00000003957	G1/S-specific cyclin-D1; Belongs to the cyclin family.	G1/S-specific cyclin-E2 isoform X2; Belongs to the cyclin family.	0.577
CCND1	CCNH	ENSVVUP00000006071	ENSVVUP00000031015	G1/S-specific cyclin-D1; Belongs to the cyclin family.	LOW QUALITY PROTEIN: cyclin-H; Belongs to the cyclin family.	0.569
CCND1	CDK2	ENSVVUP00000006071	ENSVVUP00000030368	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily.	0.995
CCND1	CDK3	ENSVVUP00000006071	ENSVVUP00000020255	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily.	0.802
CCND1	CDK4	ENSVVUP00000006071	ENSVVUP00000022976	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.999
CCND1	CDK6	ENSVVUP00000006071	ENSVVUP00000020891	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.	0.999
CCND1	CDK7	ENSVVUP00000006071	ENSVVUP00000009082	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily.	0.626
CCND1	CDKN1A	ENSVVUP00000006071	ENSVVUP00000036825	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1.	0.998
CCND1	CDKN1B	ENSVVUP00000006071	ENSVVUP00000006052	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1B.	0.987
CCND1	CDKN1C	ENSVVUP00000006071	ENSVVUP00000004315	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase inhibitor 1C.	0.876
CCND1	CDKN2C	ENSVVUP00000006071	ENSVVUP00000007987	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 4 inhibitor C.	0.964