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| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6. (389 aa) |
| | CDK3 | Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily. (305 aa) |
| | ENSVVUP00000020720 | annotation not available (254 aa) |
| | MCM9 | DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1141 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (243 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (245 aa) |
| | UBE2C | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (176 aa) |
| | ANAPC7 | Anaphase-promoting complex subunit 7 isoform X1. (598 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (776 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5. (755 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (395 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (324 aa) |
| | ENSVVUP00000023775 | annotation not available (63 aa) |
| | ENSVVUP00000023844 | annotation not available (87 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (865 aa) |
| | CDC23 | Cell division cycle protein 23 homolog isoform X1. (597 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | ORC2 | Origin recognition complex subunit 2. (574 aa) |
| | ENSVVUP00000026875 | annotation not available (107 aa) |
| | PSMB5 | Proteasome subunit beta. (277 aa) |
| | PSMB11 | Proteasome subunit beta. (327 aa) |
| | PSMA6 | Proteasome subunit alpha type. (228 aa) |
| | POLD1 | DNA polymerase. (1107 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1054 aa) |
| | ENSVVUP00000027737 | annotation not available (222 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 isoform X1. (410 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | ENSVVUP00000029975 | annotation not available (85 aa) |
| | ENSVVUP00000030237 | annotation not available (144 aa) |
| | GINS1 | DNA replication complex GINS protein PSF1 isoform X2. (224 aa) |
| | ANAPC16 | Anaphase-promoting complex subunit 16 isoform X1. (110 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (653 aa) |
| | LIG1 | DNA ligase. (911 aa) |
| | MCM8 | DNA helicase MCM8; Belongs to the MCM family. (868 aa) |
| | PSMC3 | 26S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (763 aa) |
| | GINS3 | DNA replication complex GINS protein PSF3. (228 aa) |
| | PSME3 | Proteasome activator complex subunit 3. (247 aa) |
| | ENSVVUP00000033526 | annotation not available (137 aa) |
| | ENSVVUP00000033527 | annotation not available (166 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | POLD3 | DNA polymerase delta subunit 3 isoform X1. (466 aa) |
| | LOC112910913 | Ubiquitin-like. (77 aa) |
| | ENSVVUP00000033877 | annotation not available (238 aa) |
| | RFC2 | Replication factor C subunit 2 isoform X1. (496 aa) |
| | PSMB8 | Proteasome subunit beta. (306 aa) |
| | PSMB9 | Proteasome subunit beta. (209 aa) |
| | ANAPC15 | Anaphase-promoting complex subunit 15 isoform X2. (133 aa) |
| | ENSVVUP00000035544 | annotation not available (382 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1037 aa) |
| | UBC | polyubiquitin-C. (190 aa) |
| | ENSVVUP00000036620 | annotation not available (157 aa) |
| | RFC3 | Replication factor C subunit 3 isoform X1. (355 aa) |
| | CCNA1 | cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa) |
| | FAM89B | Leucine repeat adapter protein 25. (192 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (586 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1. (531 aa) |
| | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | RCBTB2 | RCC1 and BTB domain-containing protein 2 isoform X2. (443 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1. (1943 aa) |
| | ENSVVUP00000040094 | annotation not available (128 aa) |
| | PSME1 | Proteasome activator complex subunit 1. (279 aa) |
| | PSME2 | Proteasome activator complex subunit 2 isoform X1. (239 aa) |
| | ENSVVUP00000041103 | annotation not available (105 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (836 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMC6 | 26S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (531 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (568 aa) |
| | RFC1 | Replication factor C subunit 1. (1166 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | CDC16 | Cell division cycle protein 16 homolog isoform X1. (620 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (431 aa) |
| | RFC4 | Replication factor C subunit 4. (424 aa) |
| | RFC5 | Replication factor C subunit 5. (331 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (452 aa) |
| | ENSVVUP00000017628 | annotation not available (263 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (410 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | POLA1 | DNA polymerase. (1467 aa) |
| | RPA2 | Replication protein A 32 kDa subunit isoform X2. (269 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5. (1882 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | ENSVVUP00000016277 | annotation not available (152 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5. (461 aa) |
| | ENSVVUP00000016245 | annotation not available (152 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | ENSVVUP00000014764 | annotation not available (139 aa) |
| | SKP2 | S-phase kinase-associated protein 2. (436 aa) |
| | ENSVVUP00000014607 | annotation not available (200 aa) |
| | POLD4 | DNA polymerase delta subunit 4. (107 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform X1. (772 aa) |
| | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein. (471 aa) |
| | RPS27A | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | PSMB7 | Proteasome subunit beta. (239 aa) |
| | ENSVVUP00000012574 | annotation not available (262 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (196 aa) |
| | PRIM2 | DNA primase large subunit. (469 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19. (209 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (469 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit isoform X1. (418 aa) |
| | UBA52 | ubiquitin-60S ribosomal protein L40. (231 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | PSME4 | Proteasome activator complex subunit 4. (1823 aa) |
| | ENSVVUP00000010304 | annotation not available (270 aa) |
| | UBE2S | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | ENSVVUP00000009448 | annotation not available (262 aa) |
| | PSMB1 | Proteasome subunit beta. (294 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa) |
| | LOC112926201 | LOW QUALITY PROTEIN: replication factor C subunit 5-like. (304 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2279 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 isoform X1. (456 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | CDC27 | Cell division cycle protein 27 homolog isoform X1. (825 aa) |
| | LOC112919437 | Proteasome subunit alpha type-1-like. (265 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa) |
| | ENSVVUP00000005490 | annotation not available (72 aa) |
| | LOC112923316 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa) |
| | MYRF-2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | ENSVVUP00000005276 | annotation not available (161 aa) |
| | ENSVVUP00000005165 | annotation not available (81 aa) |
| | POLE4 | DNA polymerase epsilon subunit 4. (118 aa) |
| | CDT1 | DNA replication factor Cdt1. (512 aa) |
| | FZR1 | Fizzy-related protein homolog isoform X2. (571 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (306 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X2; Belongs to the cyclin family. (404 aa) |
| | PSMA5 | Proteasome subunit alpha type. (264 aa) |
| | GMNN | Geminin. (250 aa) |
| | ENSVVUP00000003182 | annotation not available (261 aa) |
| | CDC26 | Anaphase-promoting complex subunit CDC26 isoform X2. (125 aa) |
| | PSMB3 | Proteasome subunit beta. (196 aa) |
| | PSMA8 | Proteasome endopeptidase complex. (405 aa) |
| | ORC6 | Origin recognition complex subunit 6. (392 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (516 aa) |
| | PSMB2 | Proteasome subunit beta. (189 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11 isoform X1. (84 aa) |
| | ENSVVUP00000000145 | annotation not available (84 aa) |
| | UBE2E2 | Ubiquitin-conjugating enzyme E2 E2. (202 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (253 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (825 aa) |
