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| | RPA3 | Replication protein A 14 kDa subunit. (245 aa) |
| | LOC112911984 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC112911986 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | CENPQ | Centromere protein Q isoform X1. (268 aa) |
| | ANKRD66 | Ankyrin repeat domain-containing protein 66. (160 aa) |
| | TINF2 | LOW QUALITY PROTEIN: TERF1-interacting nuclear factor 2. (167 aa) |
| | RCBTB2 | RCC1 and BTB domain-containing protein 2 isoform X2. (443 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1. (531 aa) |
| | CTC1 | CST complex subunit CTC1 isoform X2. (1299 aa) |
| | WRAP53 | Telomerase Cajal body protein 1 isoform X2. (539 aa) |
| | LOC112934396 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (586 aa) |
| | CENPN | Centromere protein N isoform X1. (339 aa) |
| | OIP5 | Protein Mis18-beta. (233 aa) |
| | CCNA1 | cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa) |
| | KNL1 | Kinetochore scaffold 1. (2152 aa) |
| | RFC3 | Replication factor C subunit 3 isoform X1. (355 aa) |
| | ANKRD44 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1. (1069 aa) |
| | DAXX | Death domain-associated protein 6 isoform X2. (733 aa) |
| | PPP6R2 | Serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1. (923 aa) |
| | HJURP | Holliday junction recognition protein. (724 aa) |
| | ENSVVUP00000035209 | annotation not available (103 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | NOP10 | H/ACA ribonucleoprotein complex subunit 3. (64 aa) |
| | ENSVVUP00000035151 | annotation not available (103 aa) |
| | ENSVVUP00000035131 | annotation not available (129 aa) |
| | LOC112910316-2 | Histone H2B type 1. (126 aa) |
| | RFC2 | Replication factor C subunit 2 isoform X1. (496 aa) |
| | TERF2IP | Telomeric repeat-binding factor 2-interacting protein 1. (406 aa) |
| | ENSVVUP00000034126 | annotation not available (114 aa) |
| | POLD3 | DNA polymerase delta subunit 3 isoform X1. (466 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | H2AX | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | RSF1 | Remodeling and spacing factor 1 isoform X1. (1434 aa) |
| | LIG1 | DNA ligase. (911 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (512 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1098 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | ENSVVUP00000029866 | annotation not available (67 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | ENSVVUP00000029631 | annotation not available (489 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa) |
| | DKC1 | H/ACA ribonucleoprotein complex subunit DKC1. (580 aa) |
| | H2BC11 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC112910324 | Histone H4. (103 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1054 aa) |
| | ENSVVUP00000027572 | annotation not available (103 aa) |
| | ENSVVUP00000027565 | annotation not available (103 aa) |
| | POLD1 | DNA polymerase. (1107 aa) |
| | ENSVVUP00000027538 | annotation not available (149 aa) |
| | WRN | Werner syndrome ATP-dependent helicase. (1455 aa) |
| | LOC112923335 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (432 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | ENSVVUP00000024333 | annotation not available (274 aa) |
| | GAR1 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (219 aa) |
| | SMARCA5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa) |
| | TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (528 aa) |
| | ITGB3BP | Centromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. (180 aa) |
| | CENPA | Histone H3-like centromeric protein A. (123 aa) |
| | DSCC1 | Sister chromatid cohesion protein DCC1 isoform X1. (422 aa) |
| | LOC112911809 | Nucleophosmin-like isoform X1. (269 aa) |
| | RBBP4 | Histone-binding protein RBBP4 isoform X1. (425 aa) |
| | ENSVVUP00000020720 | annotation not available (254 aa) |
| | CENPO | Centromere protein O. (297 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1232 aa) |
| | CDK3 | Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily. (305 aa) |
| | ENSVVUP00000020247 | annotation not available (119 aa) |
| | LOC112920814 | CST complex subunit TEN1 isoform X5. (121 aa) |
| | LOC112920802 | Histone H3.3. (136 aa) |
| | RFC1 | Replication factor C subunit 1. (1166 aa) |
| | RBBP7 | Histone-binding protein RBBP7 isoform X3. (469 aa) |
| | CENPL | Centromere protein L. (343 aa) |
| | SHQ1 | Protein SHQ1 homolog. (579 aa) |
| | RBPMS2 | RNA-binding protein with multiple splicing 2. (244 aa) |
| | ATRX | Transcriptional regulator ATRX isoform X1. (2488 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (431 aa) |
| | RFC4 | Replication factor C subunit 4. (424 aa) |
| | RFC5 | Replication factor C subunit 5. (331 aa) |
| | CENPU | Centromere protein U. (431 aa) |
| | CENPT | Centromere protein T. (572 aa) |
| | POLA1 | DNA polymerase. (1467 aa) |
| | ACD | Adrenocortical dysplasia protein homolog isoform X2. (400 aa) |
| | CHTF18 | Chromosome transmission fidelity protein 18 homolog. (1099 aa) |
| | RPA2 | Replication protein A 32 kDa subunit isoform X2. (269 aa) |
| | LOC112911708 | Histone H2A.V. (237 aa) |
| | POLD4 | DNA polymerase delta subunit 4. (107 aa) |
| | TRUB1 | Probable tRNA pseudouridine synthase 1. (415 aa) |
| | PPP6C | Serine/threonine-protein phosphatase. (305 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein. (471 aa) |
| | SMARCA1 | Probable global transcription activator SNF2L1 isoform X3. (1001 aa) |
| | PRIM2 | DNA primase large subunit. (469 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (469 aa) |
| | H2AZ1 | Histone H2A; Belongs to the histone H2A family. (230 aa) |
| | ENSVVUP00000010438 | Late histone H2B.L4-like. (67 aa) |
| | H2AC20 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | H2BC21 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC112907712 | Histone H4. (103 aa) |
| | H2BC18 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC112908299 | Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (124 aa) |
| | POT1 | Protection of telomeres protein 1 isoform X1. (731 aa) |
| | CENPH | Centromere protein H. (301 aa) |
| | LOC112926201 | LOW QUALITY PROTEIN: replication factor C subunit 5-like. (304 aa) |
| | ENSVVUP00000008883 | annotation not available (86 aa) |
| | BLM | Bloom syndrome protein. (1420 aa) |
| | LOC112923719 | Late histone H2B.L4-like; Belongs to the histone H2B family. (122 aa) |
| | CENPK | Centromere protein K isoform X1. (272 aa) |
| | CENPC | Centromere protein C isoform X1. (1020 aa) |
| | CENPP | Centromere protein P isoform X1. (313 aa) |
| | PPP6R3 | Serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1. (897 aa) |
| | CENPI | Centromere protein I. (745 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (618 aa) |
| | LOC112917557 | Histone H4. (103 aa) |
| | H2AJ | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | MYRF-2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | ENSVVUP00000005165 | annotation not available (81 aa) |
| | EXD2 | Exonuclease 3'-5' domain-containing protein 2 isoform X1. (626 aa) |
| | CENPM | Centromere protein M isoform X1. (241 aa) |
| | MIS18A | Protein Mis18-alpha. (235 aa) |
| | NPM1 | Nucleophosmin isoform X1. (292 aa) |
| | LOC112923559 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | NHP2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (180 aa) |
| | ENSVVUP00000001123 | annotation not available (140 aa) |
| | LOC112910323 | Histone H4. (103 aa) |
| | CENPW | Centromere protein W. (88 aa) |
| | ANKRD28 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1. (1083 aa) |
| | LOC112910316 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | CENPX | Centromere protein X isoform X2. (124 aa) |
| | MIS18BP1 | Mis18-binding protein 1 isoform X1. (1149 aa) |
| | ENSVVUP00000000332 | annotation not available (126 aa) |
| | LOC112910323-2 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | LOC112920488 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
