(22 nodes) Gastrin-CREB signalling pathway via PKC and MAPK network (Vulpes vulpes)

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Your Input:
	ENSVVUP00000024290	annotation not available (257 aa)
	KRAS	GTPase KRas isoform X1. (418 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	CCKBR	Gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (452 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (733 aa)
	MAPK1	Mitogen-activated protein kinase. (392 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
	EGFR	Receptor protein-tyrosine kinase. (1154 aa)
	NRAS	GTPase NRas. (189 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X3. (731 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (225 aa)
	GRB2	Growth factor receptor-bound protein 2. (351 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	MMP3	Stromelysin-1. (477 aa)
	ENSVVUP00000017517	annotation not available (118 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	ERAS	GTPase ERas. (228 aa)
	GAST	Gastrin. (104 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCKBR	GAST	ENSVVUP00000033753	ENSVVUP00000025874	Gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family.	Gastrin.	0.999
CREB1	EGFR	ENSVVUP00000016172	ENSVVUP00000013448	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Receptor protein-tyrosine kinase.	0.454
CREB1	MAPK1	ENSVVUP00000016172	ENSVVUP00000027843	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Mitogen-activated protein kinase.	0.933
CREB1	MAPK3	ENSVVUP00000016172	ENSVVUP00000036212	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.921
CREB1	PRKCA	ENSVVUP00000016172	ENSVVUP00000009002	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.740
CREB1	RPS6KA1	ENSVVUP00000016172	ENSVVUP00000016268	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Ribosomal protein S6 kinase.	0.682
CREB1	RPS6KA2	ENSVVUP00000016172	ENSVVUP00000029657	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Ribosomal protein S6 kinase.	0.638
CREB1	RPS6KA3	ENSVVUP00000016172	ENSVVUP00000017691	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Ribosomal protein S6 kinase.	0.678
CSDE1	EGFR	ENSVVUP00000013458	ENSVVUP00000013448	Cold shock domain-containing protein E1 isoform X3.	Receptor protein-tyrosine kinase.	0.508
CSDE1	GRB2	ENSVVUP00000013458	ENSVVUP00000015427	Cold shock domain-containing protein E1 isoform X3.	Growth factor receptor-bound protein 2.	0.580
CSDE1	SOS1	ENSVVUP00000013458	ENSVVUP00000025481	Cold shock domain-containing protein E1 isoform X3.	Son of sevenless homolog 1 isoform X1.	0.649
EGFR	CREB1	ENSVVUP00000013448	ENSVVUP00000016172	Receptor protein-tyrosine kinase.	Cyclic AMP-responsive element-binding protein 1 isoform X1.	0.454
EGFR	CSDE1	ENSVVUP00000013448	ENSVVUP00000013458	Receptor protein-tyrosine kinase.	Cold shock domain-containing protein E1 isoform X3.	0.508
EGFR	ERAS	ENSVVUP00000013448	ENSVVUP00000024241	Receptor protein-tyrosine kinase.	GTPase ERas.	0.537
EGFR	GRB2	ENSVVUP00000013448	ENSVVUP00000015427	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2.	0.999
EGFR	HBEGF	ENSVVUP00000013448	ENSVVUP00000013818	Receptor protein-tyrosine kinase.	Proheparin-binding EGF-like growth factor.	0.999
EGFR	HRAS	ENSVVUP00000013448	ENSVVUP00000023461	Receptor protein-tyrosine kinase.	GTPase HRas isoform X1.	0.980
EGFR	KRAS	ENSVVUP00000013448	ENSVVUP00000042700	Receptor protein-tyrosine kinase.	GTPase KRas isoform X1.	0.989
EGFR	NRAS	ENSVVUP00000013448	ENSVVUP00000013453	Receptor protein-tyrosine kinase.	GTPase NRas.	0.980
EGFR	PRKCA	ENSVVUP00000013448	ENSVVUP00000009002	Receptor protein-tyrosine kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.516