STRINGSTRING
XPO1 XPO1 PPP2R5B PPP2R5B BUB1 BUB1 CLASP1 CLASP1 CENPN CENPN CKAP5 CKAP5 LOC112907400 LOC112907400 KNL1 KNL1 BUB1B BUB1B TAOK2 TAOK2 ENSVVUP00000036042 ENSVVUP00000036042 SGO2 SGO2 LOC112906974 LOC112906974 TUBA4A TUBA4A LOC112922521 LOC112922521 NUP98 NUP98 ENSVVUP00000035680 ENSVVUP00000035680 ERCC6L ERCC6L ENSVVUP00000035233 ENSVVUP00000035233 ENSVVUP00000034938 ENSVVUP00000034938 EML4 EML4 CLIP2 CLIP2 SEC13 SEC13 CDCA8 CDCA8 NUP160 NUP160 ERCC6L2 ERCC6L2 CLASP2 CLASP2 PAFAH1B1 PAFAH1B1 ENSVVUP00000029378 ENSVVUP00000029378 PPP2CA PPP2CA CDC20B CDC20B LOC112927603 LOC112927603 LOC112934979 LOC112934979 DYNLL1 DYNLL1 TAOK1 TAOK1 TUBA1C TUBA1C LOC112921105 LOC112921105 RANBP2 RANBP2 PPP2CB PPP2CB NDE1 NDE1 ENSVVUP00000026085 ENSVVUP00000026085 TUBB2A TUBB2A ENSVVUP00000025908 ENSVVUP00000025908 KNTC1 KNTC1 MEIOC MEIOC NUP37 NUP37 SPC24 SPC24 CLIP1 CLIP1 SPC25 SPC25 ITGB3BP ITGB3BP PPP1CC PPP1CC TUBB1 TUBB1 ZW10 ZW10 MAPRE3 MAPRE3 CENPA CENPA PPP2R1B PPP2R1B DYNC1I1 DYNC1I1 DYNC1I2 DYNC1I2 LOC112907905 LOC112907905 LOC112916520 LOC112916520 ENSVVUP00000020848 ENSVVUP00000020848 CENPO CENPO ZWILCH ZWILCH CENPL CENPL SKA1-2 SKA1-2 LOC112907286 LOC112907286 SEH1L SEH1L TUBB6 TUBB6 ENSVVUP00000018278 ENSVVUP00000018278 CENPU CENPU ENSVVUP00000017330 ENSVVUP00000017330 CENPT CENPT NUDC NUDC MAPRE2 MAPRE2 ENSVVUP00000016274 ENSVVUP00000016274 DYNLL2 DYNLL2 NUDCD3 NUDCD3 ENSVVUP00000016152 ENSVVUP00000016152 ENSVVUP00000015834 ENSVVUP00000015834 KIF2B KIF2B ENSVVUP00000015552 ENSVVUP00000015552 RPS27L RPS27L NUP85 NUP85 MAPRE1 MAPRE1 PPP2R1A PPP2R1A SKA1 SKA1 NUP107 NUP107 NUF2 NUF2 ENSVVUP00000013341 ENSVVUP00000013341 EML6 EML6 NEK6 NEK6 CENPE CENPE MTUS2 MTUS2 ZWINT ZWINT CDC20 CDC20 CENPF CENPF NSL1 NSL1 PPP2R5A PPP2R5A KIF2C KIF2C NDC80 NDC80 TUBAL3 TUBAL3 ENSVVUP00000009382 ENSVVUP00000009382 ENSVVUP00000009373 ENSVVUP00000009373 KIF18A KIF18A SGO1 SGO1 AHCTF1 AHCTF1 LOC112914075 LOC112914075 ENSVVUP00000001888 ENSVVUP00000001888 ENSVVUP00000002212 ENSVVUP00000002212 AURKC AURKC LOC112916281 LOC112916281 SPDL1 SPDL1 CENPM CENPM EML2 EML2 RANGAP1 RANGAP1 NUDCD2 NUDCD2 INCENP INCENP ENSVVUP00000004945 ENSVVUP00000004945 MAD1L1 MAD1L1 ENSVVUP00000005393 ENSVVUP00000005393 TUBB3 TUBB3 CENPI CENPI DYNC1LI1 DYNC1LI1 NUP43 NUP43 KIF2A KIF2A CENPP CENPP LOC112911081 LOC112911081 MAPRE1-2 MAPRE1-2 CENPC CENPC CENPK CENPK PMF1 PMF1 PLK1 PLK1 BUB3 BUB3 NUP133 NUP133 LOC112934546 LOC112934546 TUBE1 TUBE1 CENPH CENPH ENSVVUP00000042159 ENSVVUP00000042159 EML3 EML3 NEK7 NEK7 PPP2R5E PPP2R5E TUBB4B TUBB4B DSN1 DSN1 CENPQ CENPQ RCC2 RCC2 ENSVVUP00000040546 ENSVVUP00000040546 ENSVVUP00000040442 ENSVVUP00000040442 ENSVVUP00000040212 ENSVVUP00000040212 DYNC1H1-2 DYNC1H1-2 DYNC1H1 DYNC1H1 PPP2R5C PPP2R5C EML1 EML1 NDEL1 NDEL1 AURKB AURKB EML5 EML5 PPP2R5D PPP2R5D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XPO1Exportin-1 isoform X1. (1071 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
BUB1Mitotic checkpoint serine/threonine-protein kinase BUB1. (1084 aa)
CLASP1CLIP-associating protein 1 isoform X4. (1551 aa)
CENPNCentromere protein N isoform X1. (339 aa)
CKAP5Cytoskeleton-associated protein 5 isoform X1. (2033 aa)
LOC112907400Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (211 aa)
KNL1Kinetochore scaffold 1. (2152 aa)
BUB1BMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1158 aa)
TAOK2Serine/threonine-protein kinase TAO2 isoform X4. (1179 aa)
ENSVVUP00000036042annotation not available (88 aa)
SGO2Shugoshin 2. (1425 aa)
LOC11290697440S ribosomal protein S27. (98 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (659 aa)
LOC112922521Tubulin alpha chain. (416 aa)
NUP98Nuclear pore complex protein Nup98-Nup96 isoform X2. (1800 aa)
ENSVVUP00000035680annotation not available (126 aa)
ERCC6LDNA excision repair protein ERCC-6-like. (1269 aa)
ENSVVUP00000035233annotation not available (122 aa)
ENSVVUP00000034938annotation not available (125 aa)
EML4Echinoderm microtubule-associated protein-like 4 isoform X1. (1018 aa)
CLIP2CAP-Gly domain-containing linker protein 2 isoform X1. (1049 aa)
SEC13Protein SEC13 homolog; Belongs to the WD repeat SEC13 family. (308 aa)
CDCA8Borealin. (278 aa)
NUP160Nuclear pore complex protein Nup160. (1402 aa)
ERCC6L2DNA excision repair protein ERCC-6-like 2. (1550 aa)
CLASP2CLIP-associating protein 2 isoform X11. (1508 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
ENSVVUP00000029378annotation not available (285 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CDC20BCell division cycle protein 20 homolog B isoform X1. (489 aa)
LOC112927603Tubulin alpha chain-like. (436 aa)
LOC112934979Uncharacterized protein LOC112934979 isoform X1. (219 aa)
DYNLL1Dynein light chain. (88 aa)
TAOK1Serine/threonine-protein kinase TAO1 isoform X1. (1001 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (495 aa)
LOC112921105Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (385 aa)
RANBP2E3 SUMO-protein ligase RanBP2 isoform X4. (3265 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
NDE1Nuclear distribution protein nudE homolog 1. (346 aa)
ENSVVUP00000026085annotation not available (190 aa)
TUBB2ATubulin beta chain-like. (412 aa)
ENSVVUP00000025908annotation not available (294 aa)
KNTC1Kinetochore-associated protein 1. (2221 aa)
MEIOCMeiosis-specific coiled-coil domain-containing protein MEIOC. (940 aa)
NUP37Nucleoporin Nup37. (326 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (252 aa)
CLIP1CAP-Gly domain-containing linker protein 1 isoform X3. (2183 aa)
SPC25Kinetochore protein Spc25. (226 aa)
ITGB3BPCentromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. (180 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
ZW10Centromere/kinetochore protein zw10 homolog isoform X1. (779 aa)
MAPRE3Microtubule-associated protein RP/EB family member 3 isoform X1. (281 aa)
CENPAHistone H3-like centromeric protein A. (123 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (656 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X2. (703 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2 isoform X5. (632 aa)
LOC112907905Protein MIS12 homolog. (205 aa)
LOC112916520Protein MIS12 homolog. (211 aa)
ENSVVUP00000020848annotation not available (89 aa)
CENPOCentromere protein O. (297 aa)
ZWILCHProtein zwilch homolog isoform X1. (631 aa)
CENPLCentromere protein L. (343 aa)
SKA1-2Spindle and kinetochore-associated protein 1. (104 aa)
LOC112907286Spindle and kinetochore-associated protein 2. (93 aa)
SEH1LNucleoporin SEH1 isoform X3; Belongs to the WD repeat SEC13 family. (478 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (451 aa)
ENSVVUP00000018278Tubulin alpha-3 chain. (90 aa)
CENPUCentromere protein U. (431 aa)
ENSVVUP00000017330annotation not available (89 aa)
CENPTCentromere protein T. (572 aa)
NUDCNuclear migration protein nudC. (398 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2 isoform X1. (493 aa)
ENSVVUP00000016274annotation not available (188 aa)
DYNLL2Dynein light chain. (89 aa)
NUDCD3nudC domain-containing protein 3. (355 aa)
ENSVVUP00000016152annotation not available (111 aa)
ENSVVUP00000015834annotation not available (109 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (679 aa)
ENSVVUP00000015552annotation not available (85 aa)
RPS27L40S ribosomal protein S27. (93 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (659 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (195 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
SKA1Spindle and kinetochore-associated protein 1. (119 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (927 aa)
NUF2Kinetochore protein Nuf2. (464 aa)
ENSVVUP00000013341annotation not available (96 aa)
EML6Echinoderm microtubule-associated protein-like 6 isoform X3. (1965 aa)
NEK6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (451 aa)
CENPECentromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2396 aa)
MTUS2Microtubule-associated tumor suppressor candidate 2 isoform X1. (1381 aa)
ZWINTZW10 interactor. (288 aa)
CDC20Cell division cycle protein 20 homolog. (525 aa)
CENPFCentromere protein F. (3062 aa)
NSL1Kinetochore-associated protein NSL1 homolog isoform X1. (337 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (493 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (671 aa)
NDC80Kinetochore protein NDC80 homolog. (642 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
ENSVVUP00000009382annotation not available (121 aa)
ENSVVUP00000009373annotation not available (154 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (899 aa)
SGO1Shugoshin 1. (524 aa)
AHCTF1Protein ELYS isoform X1. (2383 aa)
LOC11291407540S ribosomal protein S27. (98 aa)
ENSVVUP00000001888annotation not available (199 aa)
ENSVVUP00000002212annotation not available (172 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
LOC11291628140S ribosomal protein S27-like. (84 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (621 aa)
CENPMCentromere protein M isoform X1. (241 aa)
EML2Echinoderm microtubule-associated protein-like 2 isoform X1. (849 aa)
RANGAP1Ran GTPase-activating protein 1 isoform X1. (587 aa)
NUDCD2nudC domain-containing protein 2. (192 aa)
INCENPInner centromere protein isoform X1. (929 aa)
ENSVVUP00000004945annotation not available (98 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (782 aa)
ENSVVUP00000005393annotation not available (155 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CENPICentromere protein I. (745 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (495 aa)
NUP43Nucleoporin Nup43. (380 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (729 aa)
CENPPCentromere protein P isoform X1. (313 aa)
LOC112911081Mitotic spindle assembly checkpoint protein MAD2A. (190 aa)
MAPRE1-2Microtubule-associated protein RP/EB family member 1. (126 aa)
CENPCCentromere protein C isoform X1. (1020 aa)
CENPKCentromere protein K isoform X1. (272 aa)
PMF1Polyamine-modulated factor 1 isoform X2. (202 aa)
PLK1Serine/threonine-protein kinase PLK. (607 aa)
BUB3Mitotic checkpoint protein BUB3 isoform X2. (330 aa)
NUP133Nuclear pore complex protein Nup133. (1182 aa)
LOC112934546Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (477 aa)
TUBE1Tubulin epsilon chain isoform X1; Belongs to the tubulin family. (475 aa)
CENPHCentromere protein H. (301 aa)
ENSVVUP00000042159annotation not available (59 aa)
EML3Echinoderm microtubule-associated protein-like 3 isoform X1. (896 aa)
NEK7Serine/threonine-protein kinase Nek7; Belongs to the protein kinase superfamily. (302 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (498 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
DSN1Kinetochore-associated protein DSN1 homolog. (410 aa)
CENPQCentromere protein Q isoform X1. (268 aa)
RCC2Protein RCC2. (519 aa)
ENSVVUP00000040546annotation not available (324 aa)
ENSVVUP00000040442annotation not available (64 aa)
ENSVVUP00000040212annotation not available (169 aa)
DYNC1H1-2Cytoplasmic dynein 1 heavy chain 1. (228 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (697 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (543 aa)
EML1Echinoderm microtubule-associated protein-like 1. (866 aa)
NDEL1Nuclear distribution protein nudE-like 1 isoform X1. (345 aa)
AURKBAurora kinase B isoform X3; Belongs to the protein kinase superfamily. (501 aa)
EML5Echinoderm microtubule-associated protein-like 5. (1927 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (604 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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