(25 nodes) Sealing of the nuclear envelope (NE) by ESCRT-III network (Vulpes vulpes)

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second shell of interactors

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Predicted Interactions

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Your Input:
	CC2D1B	Coiled-coil and C2 domain-containing protein 1B isoform X2. (856 aa)
	MDP1	LOW QUALITY PROTEIN: magnesium-dependent phosphatase 1-like. (157 aa)
	CHMP4A	Charged multivesicular body protein 4a isoform X2. (222 aa)
	TM9SF1	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (606 aa)
	CHMP3	Charged multivesicular body protein 3 isoform X2. (249 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (588 aa)
	CC2D1A	Coiled-coil and C2 domain-containing protein 1A isoform X1. (1067 aa)
	LEMD2	LEM domain-containing protein 2 isoform X2. (329 aa)
	ENSVVUP00000035233	annotation not available (122 aa)
	CUNH17orf75	Protein Njmu-R1. (404 aa)
	CHMP2B	Charged multivesicular body protein 2b. (221 aa)
	CHMP6	Charged multivesicular body protein 6. (184 aa)
	FIGN	Fidgetin; Belongs to the AAA ATPase family. (385 aa)
	IST1	IST1 homolog isoform X1. (366 aa)
	VPS4A	Vacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (518 aa)
	FIGNL1	Fidgetin-like protein 1; Belongs to the AAA ATPase family. (676 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (540 aa)
	CHMP4B	Charged multivesicular body protein 4b. (224 aa)
	IQCA1L	IQ and AAA domain-containing protein 1-like. (829 aa)
	TUBB3	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	CHMP2A	Charged multivesicular body protein 2a isoform X2. (222 aa)
	ENSVVUP00000001888	annotation not available (199 aa)
	CHMP4C	Charged multivesicular body protein 4c. (236 aa)
	LOC112934546	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (477 aa)
	CHMP7	Charged multivesicular body protein 7. (450 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CC2D1A	CHMP2A	ENSVVUP00000037403	ENSVVUP00000004080	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 2a isoform X2.	0.643
CC2D1A	CHMP2B	ENSVVUP00000037403	ENSVVUP00000026088	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 2b.	0.584
CC2D1A	CHMP3	ENSVVUP00000037403	ENSVVUP00000040288	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 3 isoform X2.	0.644
CC2D1A	CHMP4B	ENSVVUP00000037403	ENSVVUP00000005846	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 4b.	0.743
CC2D1A	CHMP4C	ENSVVUP00000037403	ENSVVUP00000001415	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 4c.	0.743
CC2D1A	CHMP6	ENSVVUP00000037403	ENSVVUP00000025291	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 6.	0.769
CC2D1A	CHMP7	ENSVVUP00000037403	ENSVVUP00000006564	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Charged multivesicular body protein 7.	0.623
CC2D1A	CUNH17orf75	ENSVVUP00000037403	ENSVVUP00000028174	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Protein Njmu-R1.	0.521
CC2D1A	FIGN	ENSVVUP00000037403	ENSVVUP00000025276	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Fidgetin; Belongs to the AAA ATPase family.	0.429
CC2D1A	FIGNL1	ENSVVUP00000037403	ENSVVUP00000013713	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Fidgetin-like protein 1; Belongs to the AAA ATPase family.	0.429
CC2D1A	IQCA1L	ENSVVUP00000037403	ENSVVUP00000010447	Coiled-coil and C2 domain-containing protein 1A isoform X1.	IQ and AAA domain-containing protein 1-like.	0.402
CC2D1A	IST1	ENSVVUP00000037403	ENSVVUP00000024014	Coiled-coil and C2 domain-containing protein 1A isoform X1.	IST1 homolog isoform X1.	0.637
CC2D1A	KATNAL2	ENSVVUP00000037403	ENSVVUP00000039569	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.408
CC2D1A	SPAST	ENSVVUP00000037403	ENSVVUP00000011484	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	0.459
CC2D1A	TM9SF1	ENSVVUP00000037403	ENSVVUP00000040965	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.685
CC2D1A	VPS4A	ENSVVUP00000037403	ENSVVUP00000023183	Coiled-coil and C2 domain-containing protein 1A isoform X1.	Vacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family.	0.525
CC2D1B	CHMP2A	ENSVVUP00000006029	ENSVVUP00000004080	Coiled-coil and C2 domain-containing protein 1B isoform X2.	Charged multivesicular body protein 2a isoform X2.	0.692
CC2D1B	CHMP2B	ENSVVUP00000006029	ENSVVUP00000026088	Coiled-coil and C2 domain-containing protein 1B isoform X2.	Charged multivesicular body protein 2b.	0.603
CC2D1B	CHMP3	ENSVVUP00000006029	ENSVVUP00000040288	Coiled-coil and C2 domain-containing protein 1B isoform X2.	Charged multivesicular body protein 3 isoform X2.	0.644
CC2D1B	CHMP4A	ENSVVUP00000006029	ENSVVUP00000040968	Coiled-coil and C2 domain-containing protein 1B isoform X2.	Charged multivesicular body protein 4a isoform X2.	0.565