STRINGSTRING
TRIM21 TRIM21 SRXN1 SRXN1 PSMF1 PSMF1 UBA52 UBA52 PSMA4 PSMA4 PSME4 PSME4 ENSVVUP00000010304 ENSVVUP00000010304 PRDX1 PRDX1 ENSVVUP00000009448 ENSVVUP00000009448 PSMB1 PSMB1 RBX1 RBX1 ENSVVUP00000040094 ENSVVUP00000040094 PSME1 PSME1 PSME2 PSME2 ENSVVUP00000041103 ENSVVUP00000041103 MUL1 MUL1 PSMA3 PSMA3 PSMC6 PSMC6 EP300 EP300 PSMA2 PSMA2 PSMD12 PSMD12 PSMC5 PSMC5 PSMC4 PSMC4 AKT2 AKT2 SESN1 SESN1 LOC112919437 LOC112919437 MAP1LC3A MAP1LC3A ENSVVUP00000005490 ENSVVUP00000005490 LOC112923316 LOC112923316 ENSVVUP00000005276 ENSVVUP00000005276 MAFK MAFK KLHL17 KLHL17 TRIM58 TRIM58 KLHL18 KLHL18 NFE2L1 NFE2L1 AKT1 AKT1 MTFP1 MTFP1 PSMA5 PSMA5 ENSVVUP00000003182 ENSVVUP00000003182 PSMB3 PSMB3 PSMA8 PSMA8 SQSTM1 SQSTM1 PSMD3 PSMD3 MAP1LC3B MAP1LC3B BTRC BTRC PSMB2 PSMB2 NFE2L3 NFE2L3 ENSVVUP00000027737 ENSVVUP00000027737 PSMD11 PSMD11 ENSVVUP00000028378 ENSVVUP00000028378 SKP1 SKP1 ENSVVUP00000029975 ENSVVUP00000029975 ENSVVUP00000030237 ENSVVUP00000030237 GSK3B GSK3B PSMC3 PSMC3 PSME3 PSME3 ENSVVUP00000033526 ENSVVUP00000033526 ENSVVUP00000033527 ENSVVUP00000033527 LOC112910913 LOC112910913 ENSVVUP00000033877 ENSVVUP00000033877 PSMB8 PSMB8 PSMB9 PSMB9 UFD1 UFD1 ENSVVUP00000035544 ENSVVUP00000035544 PSMD1 PSMD1 UBC UBC CUL3 CUL3 ENSVVUP00000036620 ENSVVUP00000036620 AKT3 AKT3 VCP VCP PSMA6 PSMA6 NPLOC4 NPLOC4 PSMB11 PSMB11 PSMB5 PSMB5 ENSVVUP00000026875 ENSVVUP00000026875 PSMD14 PSMD14 KIAA2012 KIAA2012 PSMC1 PSMC1 CREBZF CREBZF KEAP1 KEAP1 PSMD7 PSMD7 PSMD13 PSMD13 CUL1 CUL1 CREBBP CREBBP PSMA7 PSMA7 PSMD6 PSMD6 BACH1 BACH1 PSMC2 PSMC2 ATF4 ATF4 SPATA5L1 SPATA5L1 BACH2 BACH2 SPATA5 SPATA5 FBXL17 FBXL17 PSMD8 PSMD8 ENSVVUP00000017628 ENSVVUP00000017628 PSMB4 PSMB4 PSMD4 PSMD4 PSMB10 PSMB10 NFE2L2 NFE2L2 SESN2 SESN2 PSMD2 PSMD2 ENSVVUP00000016277 ENSVVUP00000016277 PSMD5 PSMD5 ENSVVUP00000016245 ENSVVUP00000016245 ENSVVUP00000014764 ENSVVUP00000014764 SKP2 SKP2 ENSVVUP00000014607 ENSVVUP00000014607 PSMD10 PSMD10 GSK3A GSK3A DPP3 DPP3 PSMB6 PSMB6 RPS27A RPS27A ENSVVUP00000013477 ENSVVUP00000013477 PSMB7 PSMB7 ENSVVUP00000012574 ENSVVUP00000012574 UBXN7 UBXN7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIM21E3 ubiquitin-protein ligase TRIM21. (469 aa)
SRXN1Sulfiredoxin-1. (141 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (418 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME4Proteasome activator complex subunit 4. (1823 aa)
ENSVVUP00000010304annotation not available (270 aa)
PRDX1Peroxiredoxin-1. (262 aa)
ENSVVUP00000009448annotation not available (262 aa)
PSMB1Proteasome subunit beta. (294 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa)
ENSVVUP00000040094annotation not available (128 aa)
PSME1Proteasome activator complex subunit 1. (279 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
ENSVVUP00000041103annotation not available (105 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
EP300Histone acetyltransferase p300 isoform X1. (2430 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X1. (456 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
AKT2RAC-beta serine/threonine-protein kinase. (557 aa)
SESN1Sestrin-1 isoform X1. (544 aa)
LOC112919437Proteasome subunit alpha type-1-like. (265 aa)
MAP1LC3ALOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3A. (115 aa)
ENSVVUP00000005490annotation not available (72 aa)
LOC112923316Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
ENSVVUP00000005276annotation not available (161 aa)
MAFKTranscription factor MafK. (156 aa)
KLHL17Kelch-like protein 17 isoform X1. (646 aa)
TRIM58E3 ubiquitin-protein ligase TRIM58. (469 aa)
KLHL18Kelch-like protein 18 isoform X2. (574 aa)
NFE2L1Endoplasmic reticulum membrane sensor NFE2L1 isoform X1. (781 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MTFP1Mitochondrial fission process protein 1 isoform X2. (166 aa)
PSMA5Proteasome subunit alpha type. (264 aa)
ENSVVUP00000003182annotation not available (261 aa)
PSMB3Proteasome subunit beta. (196 aa)
PSMA8Proteasome endopeptidase complex. (405 aa)
SQSTM1Sequestosome-1. (444 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B. (115 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
PSMB2Proteasome subunit beta. (189 aa)
NFE2L3Nuclear factor erythroid 2-related factor 3. (683 aa)
ENSVVUP00000027737annotation not available (222 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (410 aa)
ENSVVUP00000028378annotation not available (135 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
ENSVVUP00000029975annotation not available (85 aa)
ENSVVUP00000030237annotation not available (144 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (459 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
PSME3Proteasome activator complex subunit 3. (247 aa)
ENSVVUP00000033526annotation not available (137 aa)
ENSVVUP00000033527annotation not available (166 aa)
LOC112910913Ubiquitin-like. (77 aa)
ENSVVUP00000033877annotation not available (238 aa)
PSMB8Proteasome subunit beta. (306 aa)
PSMB9Proteasome subunit beta. (209 aa)
UFD1Ubiquitin recognition factor in ER-associated degradation protein 1. (398 aa)
ENSVVUP00000035544annotation not available (382 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1037 aa)
UBCpolyubiquitin-C. (190 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (755 aa)
ENSVVUP00000036620annotation not available (157 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (839 aa)
PSMA6Proteasome subunit alpha type. (228 aa)
NPLOC4Nuclear protein localization protein 4 homolog. (611 aa)
PSMB11Proteasome subunit beta. (327 aa)
PSMB5Proteasome subunit beta. (277 aa)
ENSVVUP00000026875annotation not available (107 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
KIAA2012Uncharacterized protein KIAA2012 homolog. (1168 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
CREBZFCREB/ATF bZIP transcription factor isoform X1. (369 aa)
KEAP1Kelch-like ECH-associated protein 1. (624 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
CREBBPCREB-binding protein isoform X1. (2442 aa)
PSMA7Proteasome endopeptidase complex. (243 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
BACH1Transcription regulator protein BACH1. (749 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (373 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1 isoform X1. (755 aa)
BACH2Transcription regulator protein BACH2. (854 aa)
SPATA5Spermatogenesis-associated protein 5 isoform X1. (893 aa)
FBXL17F-box/LRR-repeat protein 17. (220 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (452 aa)
ENSVVUP00000017628annotation not available (263 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (410 aa)
PSMB10Proteasome subunit beta. (273 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (626 aa)
SESN2Sestrin-2. (484 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ENSVVUP00000016277annotation not available (152 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (461 aa)
ENSVVUP00000016245annotation not available (152 aa)
ENSVVUP00000014764annotation not available (139 aa)
SKP2S-phase kinase-associated protein 2. (436 aa)
ENSVVUP00000014607annotation not available (200 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
GSK3AGlycogen synthase kinase-3 alpha. (446 aa)
DPP3Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (757 aa)
PSMB6Proteasome subunit beta. (239 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
ENSVVUP00000013477annotation not available (58 aa)
PSMB7Proteasome subunit beta. (239 aa)
ENSVVUP00000012574annotation not available (262 aa)
UBXN7UBX domain-containing protein 7. (489 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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