(12 nodes) (2018) Sequence Composition and Evolution of Mammalian B Chromosomes. network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TESPA1	Protein TESPA1 isoform X1. (519 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (417 aa)
	MNS1	Meiosis-specific nuclear structural protein 1. (495 aa)
	MAPRE1-2	Microtubule-associated protein RP/EB family member 1. (126 aa)
	CENPE	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2396 aa)
	SYCP1	Synaptonemal complex protein 1 isoform X1. (915 aa)
	MAPRE1	Microtubule-associated protein RP/EB family member 1. (195 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (953 aa)
	DYNC1I2	Cytoplasmic dynein 1 intermediate chain 2 isoform X5. (632 aa)
	CCT6B	T-complex protein 1 subunit zeta-2. (582 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1070 aa)
	VRK1	Serine/threonine-protein kinase VRK1 isoform X2; Belongs to the protein kinase superfamily. (470 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCT6B	DYNC1I2	ENSVVUP00000028015	ENSVVUP00000021264	T-complex protein 1 subunit zeta-2.	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	0.497
CCT6B	MNS1	ENSVVUP00000028015	ENSVVUP00000001133	T-complex protein 1 subunit zeta-2.	Meiosis-specific nuclear structural protein 1.	0.548
CENPE	DYNC1I2	ENSVVUP00000013163	ENSVVUP00000021264	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	0.697
CENPE	KIF23	ENSVVUP00000013163	ENSVVUP00000020526	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.931
CENPE	MAPRE1	ENSVVUP00000013163	ENSVVUP00000015197	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Microtubule-associated protein RP/EB family member 1.	0.650
CENPE	MAPRE1-2	ENSVVUP00000013163	ENSVVUP00000007158	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Microtubule-associated protein RP/EB family member 1.	0.650
CENPE	MNS1	ENSVVUP00000013163	ENSVVUP00000001133	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Meiosis-specific nuclear structural protein 1.	0.442
DYNC1I2	CCT6B	ENSVVUP00000021264	ENSVVUP00000028015	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	T-complex protein 1 subunit zeta-2.	0.497
DYNC1I2	CENPE	ENSVVUP00000021264	ENSVVUP00000013163	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.697
DYNC1I2	MAPRE1	ENSVVUP00000021264	ENSVVUP00000015197	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	Microtubule-associated protein RP/EB family member 1.	0.504
DYNC1I2	MAPRE1-2	ENSVVUP00000021264	ENSVVUP00000007158	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	Microtubule-associated protein RP/EB family member 1.	0.504
DYNC1I2	MNS1	ENSVVUP00000021264	ENSVVUP00000001133	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	Meiosis-specific nuclear structural protein 1.	0.650
DYNC1I2	TESPA1	ENSVVUP00000021264	ENSVVUP00000032637	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	Protein TESPA1 isoform X1.	0.425
KIF23	CENPE	ENSVVUP00000020526	ENSVVUP00000013163	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.931
KIF23	TESPA1	ENSVVUP00000020526	ENSVVUP00000032637	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein TESPA1 isoform X1.	0.626
KIF23	VRK1	ENSVVUP00000020526	ENSVVUP00000039803	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Serine/threonine-protein kinase VRK1 isoform X2; Belongs to the protein kinase superfamily.	0.481
MAPRE1	CENPE	ENSVVUP00000015197	ENSVVUP00000013163	Microtubule-associated protein RP/EB family member 1.	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.650
MAPRE1	DYNC1I2	ENSVVUP00000015197	ENSVVUP00000021264	Microtubule-associated protein RP/EB family member 1.	Cytoplasmic dynein 1 intermediate chain 2 isoform X5.	0.504
MAPRE1	MNS1	ENSVVUP00000015197	ENSVVUP00000001133	Microtubule-associated protein RP/EB family member 1.	Meiosis-specific nuclear structural protein 1.	0.408
MAPRE1-2	CENPE	ENSVVUP00000007158	ENSVVUP00000013163	Microtubule-associated protein RP/EB family member 1.	Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.650