(7 nodes) (2019) The Australian dingo: untamed or feral? network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCG8	ATP-binding cassette sub-family G member 8. (690 aa)
	SORCS1	VPS10 domain-containing receptor SorCS1. (1151 aa)
	GTF2I	General transcription factor II-I. (563 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
	GTF2IRD1	General transcription factor II-I repeat domain-containing protein 1 isoform X1. (991 aa)
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
	ABCG5	ATP-binding cassette sub-family G member 5. (652 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG5	ABCG8	ENSVVUP00000001788	ENSVVUP00000002389	ATP-binding cassette sub-family G member 5.	ATP-binding cassette sub-family G member 8.	0.999
ABCG5	GTF2I	ENSVVUP00000001788	ENSVVUP00000020270	ATP-binding cassette sub-family G member 5.	General transcription factor II-I.	0.505
ABCG5	GTF2IRD1	ENSVVUP00000001788	ENSVVUP00000034447	ATP-binding cassette sub-family G member 5.	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	0.568
ABCG5	RUNX2	ENSVVUP00000001788	ENSVVUP00000041121	ATP-binding cassette sub-family G member 5.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.449
ABCG5	SORCS1	ENSVVUP00000001788	ENSVVUP00000010181	ATP-binding cassette sub-family G member 5.	VPS10 domain-containing receptor SorCS1.	0.665
ABCG8	ABCG5	ENSVVUP00000002389	ENSVVUP00000001788	ATP-binding cassette sub-family G member 8.	ATP-binding cassette sub-family G member 5.	0.999
ABCG8	GTF2I	ENSVVUP00000002389	ENSVVUP00000020270	ATP-binding cassette sub-family G member 8.	General transcription factor II-I.	0.504
ABCG8	GTF2IRD1	ENSVVUP00000002389	ENSVVUP00000034447	ATP-binding cassette sub-family G member 8.	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	0.567
ABCG8	RUNX2	ENSVVUP00000002389	ENSVVUP00000041121	ATP-binding cassette sub-family G member 8.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.449
ABCG8	SORCS1	ENSVVUP00000002389	ENSVVUP00000010181	ATP-binding cassette sub-family G member 8.	VPS10 domain-containing receptor SorCS1.	0.665
BMP3	RUNX2	ENSVVUP00000034245	ENSVVUP00000041121	Bone morphogenetic protein 3; Belongs to the TGF-beta family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.541
BMP3	SORCS1	ENSVVUP00000034245	ENSVVUP00000010181	Bone morphogenetic protein 3; Belongs to the TGF-beta family.	VPS10 domain-containing receptor SorCS1.	0.456
GTF2I	ABCG5	ENSVVUP00000020270	ENSVVUP00000001788	General transcription factor II-I.	ATP-binding cassette sub-family G member 5.	0.505
GTF2I	ABCG8	ENSVVUP00000020270	ENSVVUP00000002389	General transcription factor II-I.	ATP-binding cassette sub-family G member 8.	0.504
GTF2I	GTF2IRD1	ENSVVUP00000020270	ENSVVUP00000034447	General transcription factor II-I.	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	0.914
GTF2I	SORCS1	ENSVVUP00000020270	ENSVVUP00000010181	General transcription factor II-I.	VPS10 domain-containing receptor SorCS1.	0.549
GTF2IRD1	ABCG5	ENSVVUP00000034447	ENSVVUP00000001788	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	ATP-binding cassette sub-family G member 5.	0.568
GTF2IRD1	ABCG8	ENSVVUP00000034447	ENSVVUP00000002389	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	ATP-binding cassette sub-family G member 8.	0.567
GTF2IRD1	GTF2I	ENSVVUP00000034447	ENSVVUP00000020270	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	General transcription factor II-I.	0.914
GTF2IRD1	SORCS1	ENSVVUP00000034447	ENSVVUP00000010181	General transcription factor II-I repeat domain-containing protein 1 isoform X1.	VPS10 domain-containing receptor SorCS1.	0.633