(6 nodes) (2021) Clinical-Pathological Conference Series from the Medical University of Graz : Case No 172: A 45-year-old truck driver with fever, vomiting, thrombocytopenia and renal failure. network (Vulpes vulpes)

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Your Input:
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (621 aa)
	GOT2	Aspartate aminotransferase. (430 aa)
	PRL	Prolactin. (248 aa)
	IGF1	Insulin-like growth factor I isoform X1. (187 aa)
	GOT1	Aspartate aminotransferase. (616 aa)
	EPO	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPO	IGF1	ENSVVUP00000032357	ENSVVUP00000024480	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Insulin-like growth factor I isoform X1.	0.495
EPO	PRL	ENSVVUP00000032357	ENSVVUP00000003572	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Prolactin.	0.942
F2	GOT1	ENSVVUP00000037464	ENSVVUP00000032227	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Aspartate aminotransferase.	0.727
F2	GOT2	ENSVVUP00000037464	ENSVVUP00000037917	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Aspartate aminotransferase.	0.688
GOT1	F2	ENSVVUP00000032227	ENSVVUP00000037464	Aspartate aminotransferase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.727
GOT1	GOT2	ENSVVUP00000032227	ENSVVUP00000037917	Aspartate aminotransferase.	Aspartate aminotransferase.	0.979
GOT1	IGF1	ENSVVUP00000032227	ENSVVUP00000024480	Aspartate aminotransferase.	Insulin-like growth factor I isoform X1.	0.439
GOT2	F2	ENSVVUP00000037917	ENSVVUP00000037464	Aspartate aminotransferase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.688
GOT2	GOT1	ENSVVUP00000037917	ENSVVUP00000032227	Aspartate aminotransferase.	Aspartate aminotransferase.	0.979
IGF1	EPO	ENSVVUP00000024480	ENSVVUP00000032357	Insulin-like growth factor I isoform X1.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.495
IGF1	GOT1	ENSVVUP00000024480	ENSVVUP00000032227	Insulin-like growth factor I isoform X1.	Aspartate aminotransferase.	0.439
IGF1	PRL	ENSVVUP00000024480	ENSVVUP00000003572	Insulin-like growth factor I isoform X1.	Prolactin.	0.516
PRL	EPO	ENSVVUP00000003572	ENSVVUP00000032357	Prolactin.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.942
PRL	IGF1	ENSVVUP00000003572	ENSVVUP00000024480	Prolactin.	Insulin-like growth factor I isoform X1.	0.516