(27 nodes) Zinc-dependent metalloprotease network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MMP13	Collagenase 3. (470 aa)
	MMP11	Stromelysin-3. (488 aa)
	MMP14	Matrix metalloproteinase-14. (582 aa)
	MMP28	Matrix metalloproteinase-28. (498 aa)
	MMP19	Matrix metalloproteinase-19. (549 aa)
	TLL2	Metalloendopeptidase. (997 aa)
	MMP15	Matrix metalloproteinase-15. (661 aa)
	TLL1	Metalloendopeptidase. (1010 aa)
	ASTL	Metalloendopeptidase. (430 aa)
	ADAMTS13	A disintegrin and metalloproteinase with thrombospondin motifs 13. (1490 aa)
	MEP1B	Meprin A subunit. (686 aa)
	MEP1A	Meprin A subunit. (765 aa)
	MMP23B	Matrix metalloproteinase-23 isoform X1. (391 aa)
	BMP1	Metalloendopeptidase. (976 aa)
	MMP21	Matrix metalloproteinase-21. (732 aa)
	MMP25	Matrix metalloproteinase-25. (901 aa)
	MMP7	Matrilysin. (261 aa)
	MMP17	Matrix metalloproteinase-17. (627 aa)
	MMP20	Matrix metalloproteinase-20. (463 aa)
	MMP27	Matrix metalloproteinase-27. (512 aa)
	MMP8	Neutrophil collagenase. (487 aa)
	MMP1	LOW QUALITY PROTEIN: interstitial collagenase-like. (444 aa)
	MMP3	Stromelysin-1. (477 aa)
	MMP26	Matrix metalloproteinase-26. (285 aa)
	MMP16	Matrix metalloproteinase-16. (702 aa)
	MMP24	Matrix metalloproteinase-24. (605 aa)
	MMP12	Macrophage metalloelastase. (492 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP1	MMP1	ENSVVUP00000007865	ENSVVUP00000016276	Metalloendopeptidase.	LOW QUALITY PROTEIN: interstitial collagenase-like.	0.477
MEP1A	MEP1B	ENSVVUP00000041167	ENSVVUP00000038504	Meprin A subunit.	Meprin A subunit.	0.913
MEP1B	MEP1A	ENSVVUP00000038504	ENSVVUP00000041167	Meprin A subunit.	Meprin A subunit.	0.913
MMP1	BMP1	ENSVVUP00000016276	ENSVVUP00000007865	LOW QUALITY PROTEIN: interstitial collagenase-like.	Metalloendopeptidase.	0.477
MMP1	MMP11	ENSVVUP00000016276	ENSVVUP00000026528	LOW QUALITY PROTEIN: interstitial collagenase-like.	Stromelysin-3.	0.536
MMP1	MMP12	ENSVVUP00000016276	ENSVVUP00000016341	LOW QUALITY PROTEIN: interstitial collagenase-like.	Macrophage metalloelastase.	0.678
MMP1	MMP13	ENSVVUP00000016276	ENSVVUP00000016348	LOW QUALITY PROTEIN: interstitial collagenase-like.	Collagenase 3.	0.535
MMP1	MMP14	ENSVVUP00000016276	ENSVVUP00000026934	LOW QUALITY PROTEIN: interstitial collagenase-like.	Matrix metalloproteinase-14.	0.477
MMP1	MMP15	ENSVVUP00000016276	ENSVVUP00000032732	LOW QUALITY PROTEIN: interstitial collagenase-like.	Matrix metalloproteinase-15.	0.400
MMP1	MMP20	ENSVVUP00000016276	ENSVVUP00000014657	LOW QUALITY PROTEIN: interstitial collagenase-like.	Matrix metalloproteinase-20.	0.666
MMP1	MMP26	ENSVVUP00000016276	ENSVVUP00000001993	LOW QUALITY PROTEIN: interstitial collagenase-like.	Matrix metalloproteinase-26.	0.677
MMP1	MMP3	ENSVVUP00000016276	ENSVVUP00000016292	LOW QUALITY PROTEIN: interstitial collagenase-like.	Stromelysin-1.	0.966
MMP1	MMP7	ENSVVUP00000016276	ENSVVUP00000014633	LOW QUALITY PROTEIN: interstitial collagenase-like.	Matrilysin.	0.600
MMP11	MMP1	ENSVVUP00000026528	ENSVVUP00000016276	Stromelysin-3.	LOW QUALITY PROTEIN: interstitial collagenase-like.	0.536
MMP11	MMP12	ENSVVUP00000026528	ENSVVUP00000016341	Stromelysin-3.	Macrophage metalloelastase.	0.421
MMP11	MMP13	ENSVVUP00000026528	ENSVVUP00000016348	Stromelysin-3.	Collagenase 3.	0.412
MMP11	MMP19	ENSVVUP00000026528	ENSVVUP00000031221	Stromelysin-3.	Matrix metalloproteinase-19.	0.428
MMP11	MMP20	ENSVVUP00000026528	ENSVVUP00000014657	Stromelysin-3.	Matrix metalloproteinase-20.	0.510
MMP11	MMP26	ENSVVUP00000026528	ENSVVUP00000001993	Stromelysin-3.	Matrix metalloproteinase-26.	0.503
MMP11	MMP27	ENSVVUP00000026528	ENSVVUP00000014686	Stromelysin-3.	Matrix metalloproteinase-27.	0.414