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IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (782 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (207 aa) | ||||
TYMS | Thymidylate synthase isoform X1. (314 aa) | ||||
ABCC4 | Multidrug resistance-associated protein 4. (1318 aa) | ||||
ABCC5 | Multidrug resistance-associated protein 5 isoform X1. (1485 aa) | ||||
ABCG2 | ATP-binding cassette sub-family G member 2. (650 aa) | ||||
ATIC | Bifunctional purine biosynthesis protein PURH. (533 aa) | ||||
NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) | ||||
ABCC3 | Canalicular multispecific organic anion transporter 2. (1326 aa) | ||||
FPGS | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (588 aa) | ||||
SLC46A1 | Proton-coupled folate transporter. (459 aa) | ||||
SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (505 aa) | ||||
GGH | Folate gamma-glutamyl hydrolase. (318 aa) | ||||
ABCC1 | Multidrug resistance-associated protein 1. (1465 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
GART | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa) | ||||
SLC19A1 | Folate transporter 1. (500 aa) | ||||
ABCC2 | Canalicular multispecific organic anion transporter 1. (1544 aa) | ||||
CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) | ||||
FOLR2 | Folate receptor beta. (213 aa) | ||||
LOC112928755 | LOW QUALITY PROTEIN: folate receptor alpha-like. (241 aa) | ||||
RELA | Transcription factor p65 isoform X2. (542 aa) | ||||
ALOX12 | Arachidonate 12-lipoxygenase, 12S-type. (685 aa) | ||||
MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (695 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa) | ||||
IKBKG | NF-kappa-B essential modulator isoform X1. (419 aa) | ||||
SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (486 aa) |