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| | LGR4 | Leucine-rich repeat-containing G-protein coupled receptor 4. (955 aa) |
| | DKK4 | Dickkopf-related protein 4. (218 aa) |
| | BTRC | F-box/WD repeat-containing protein 1A isoform X1. (605 aa) |
| | FZD8 | LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (632 aa) |
| | RSPO3 | R-spondin-3 isoform X1. (279 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa) |
| | TBL1XR1 | F-box-like/WD repeat-containing protein TBL1XR1 isoform X1. (573 aa) |
| | ROCK2 | Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1327 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | TCF7L1 | Transcription factor 7-like 1. (567 aa) |
| | FBXW11 | F-box/WD repeat-containing protein 11 isoform X2. (593 aa) |
| | FZD3 | Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | DKK1 | Dickkopf-related protein 1. (270 aa) |
| | DVL1 | Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (466 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (386 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa) |
| | WNT3 | Wingless-type MMTV integration site family, member 3. (170 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (682 aa) |
| | CTNNB1 | Catenin beta-1 isoform X1. (781 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | RYK | Tyrosine-protein kinase RYK. (546 aa) |
| | CTBP2 | C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa) |
| | LGR6 | Leucine-rich repeat-containing G-protein coupled receptor 6. (893 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa) |
| | EP300 | Histone acetyltransferase p300 isoform X1. (2430 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa) |
| | AXIN2 | Axin-2 isoform X1. (842 aa) |
| | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2; Belongs to the protein kinase superfamily. (478 aa) |
| | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6. (533 aa) |
| | CSNK2A1 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | LGR5 | Leucine-rich repeat-containing G-protein coupled receptor 5. (296 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (572 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2535 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1630 aa) |
| | VANGL1 | Vang-like protein. (565 aa) |
| | WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa) |
| | MMP7 | Matrilysin. (261 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa) |
| | WIF1 | Wnt inhibitory factor 1. (329 aa) |
| | APC | Adenomatous polyposis coli protein isoform X1. (2862 aa) |
| | SENP2 | Sentrin-specific protease 2 isoform X1. (667 aa) |
| | RNF43 | E3 ubiquitin-protein ligase RNF43. (778 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1074 aa) |
| | CTBP1 | C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (422 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (529 aa) |
| | AXIN1 | Axin-1 isoform X1. (880 aa) |
| | FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa) |
| | GPC4 | Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) |
| | ROR1 | Inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (874 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | CACYBP | Calcyclin-binding protein. (230 aa) |
| | CSNK1A1 | Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (384 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | PRICKLE2 | Prickle-like protein 2 isoform X1. (823 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (202 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | SIAH1 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2442 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (776 aa) |
| | PRICKLE1 | Prickle-like protein 1. (832 aa) |
| | FZD6 | Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (524 aa) |
| | CXXC4 | CXXC-type zinc finger protein 4. (216 aa) |
| | SFRP4 | Secreted frizzled-related protein 4. (316 aa) |
| | RSPO2 | R-spondin-2. (243 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa) |
| | DKK2 | Dickkopf-related protein 2. (259 aa) |
| | SOST | Sclerostin. (213 aa) |
| | PRICKLE3 | Prickle planar cell polarity protein 3 isoform X2. (617 aa) |
| | CTNND2 | Catenin delta-2. (754 aa) |
| | FZD2 | Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (325 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (505 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (1004 aa) |
| | TBL1X | F-box-like/WD repeat-containing protein TBL1X isoform X2. (526 aa) |
| | PPP3R2 | Calcineurin subunit B type 2. (252 aa) |
| | CCN4 | WNT1-inducible-signaling pathway protein 1. (362 aa) |
| | INVS | Inversin isoform X1. (1092 aa) |
| | NKD1 | Protein naked cuticle homolog 1. (447 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (293 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (387 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | SERPINF1 | Pigment epithelium-derived factor; Belongs to the serpin family. (418 aa) |
| | NKD2 | Protein naked cuticle homolog 2. (424 aa) |
| | ROR2 | Tyrosine-protein kinase transmembrane receptor ROR2 isoform X2. (682 aa) |
| | CBY1 | Protein chibby homolog 1. (151 aa) |
| | NFATC2 | LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 2. (902 aa) |
| | LOC112908688 | Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (458 aa) |
| | CER1 | Cerberus. (270 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (529 aa) |
| | RSPO1 | R-spondin-1. (265 aa) |
| | CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (611 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | SFRP5 | Secreted frizzled-related protein 5. (319 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 2. (173 aa) |
| | CSNK2A2 | Casein kinase II subunit alpha. (345 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (411 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (294 aa) |
| | FZD10 | Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | ZNRF3 | E3 ubiquitin-protein ligase ZNRF3. (844 aa) |
| | PPARD | Peroxisome proliferator-activated receptor delta. (441 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa) |
| | DAAM2 | Disheveled-associated activator of morphogenesis 2 isoform X1. (1114 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (401 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (382 aa) |
| | FOSL1 | Fos-related antigen 1 isoform X1. (268 aa) |
| | PPP3R1 | Calcineurin subunit B type 1. (192 aa) |
| | DVL2 | Segment polarity protein dishevelled homolog DVL-2 isoform X4. (732 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (903 aa) |
| | DAAM1 | Disheveled-associated activator of morphogenesis 1 isoform X2. (1068 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
