STRINGSTRING
MPP5 MPP5 BTRC BTRC FZD8 FZD8 WNT10A WNT10A WNT6 WNT6 PARD3 PARD3 PRKCI PRKCI PPP2R2C PPP2R2C BMP5 BMP5 YWHAQ YWHAQ PPP2R2D PPP2R2D TCF7L1 TCF7L1 FBXW11 FBXW11 PPP1CB PPP1CB CCN2 CCN2 FZD3 FZD3 CTNNA2 CTNNA2 CRB1 CRB1 NF2 NF2 PPP2R2A PPP2R2A TP53BP2 TP53BP2 GDF5 GDF5 MOB1B MOB1B DVL1 DVL1 MOB1A MOB1A PRKCZ PRKCZ CCND1 CCND1 TGFBR2 TGFBR2 WNT9B WNT9B WNT3 WNT3 LATS1 LATS1 LOC112908263 LOC112908263 CSNK1D CSNK1D TGFB1 TGFB1 CTNNB1 CTNNB1 TGFB3 TGFB3 SOX2 SOX2 AXIN2 AXIN2 LIMD1 LIMD1 DLG3 DLG3 BMPR1B BMPR1B LATS2 LATS2 ID1 ID1 ID2 ID2 DLG1 DLG1 SMAD1 SMAD1 WNT2 WNT2 PPP1CA PPP1CA YAP1 YAP1 BIRC3 BIRC3 BIRC2 BIRC2 AMOT AMOT PPP2R1A PPP2R1A WWTR1 WWTR1 LLGL2 LLGL2 FZD5 FZD5 STK3 STK3 APC APC PARD6A PARD6A TGFB2 TGFB2 CDH1 CDH1 YWHAZ YWHAZ AXIN1 AXIN1 FZD1 FZD1 SMAD7 SMAD7 SMAD4 SMAD4 SMAD3 SMAD3 AREG AREG WNT8A WNT8A RASSF6 RASSF6 LOC112909244 LOC112909244 AFP AFP WNT2B WNT2B PPP1CC PPP1CC WTIP WTIP FZD6 FZD6 MYC MYC WNT16 WNT16 BMP7 BMP7 DLG2-2 DLG2-2 SNAI2 SNAI2 FZD2 FZD2 CCND2 CCND2 WNT7A WNT7A BMPR2 BMPR2 FZD7 FZD7 GLI2 GLI2 FZD4 FZD4 PARD6G PARD6G YWHAB YWHAB NKD1 NKD1 TGFBR1 TGFBR1 WNT10B WNT10B WNT1 WNT1 PPP2CB PPP2CB AJUBA AJUBA CTNNA1 CTNNA1 WNT5A WNT5A FGF1 FGF1 PPP2R2B PPP2R2B PPP2CA PPP2CA FRMD1 FRMD1 YWHAE YWHAE NKD2 NKD2 PARD6B PARD6B SCRIB SCRIB LOC112908688 LOC112908688 BMP2 BMP2 BBC3 BBC3 SERPINE1 SERPINE1 YWHAG YWHAG ITGB2 ITGB2 WNT11 WNT11 FZD9 FZD9 WNT7B WNT7B WNT8B WNT8B TEAD1 TEAD1 DLG5 DLG5 FZD10 FZD10 TEAD3 TEAD3 PATJ PATJ CCND3 CCND3 TP73 TP73 DVL2 DVL2 SMAD2 SMAD2 RASSF1 RASSF1 YWHAH YWHAH BMP4 BMP4 FRMD6 FRMD6 SAV1 SAV1 LLGL1 LLGL1 WNT4 WNT4 WNT3A WNT3A WNT9A WNT9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (675 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
FZD8LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (632 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
PARD3Partitioning defective 3 homolog. (1328 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (571 aa)
PPP2R2CProtein phosphatase 2, regulatory subunit B, gamma isoform X1. (405 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
YWHAQ14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (470 aa)
TCF7L1Transcription factor 7-like 1. (567 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X2. (593 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (332 aa)
CCN2Connective tissue growth factor. (464 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CTNNA2Catenin alpha-2 isoform X1. (728 aa)
CRB1Protein crumbs homolog 1. (1378 aa)
NF2Merlin isoform X1. (596 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa)
TP53BP2Apoptosis-stimulating of p53 protein 2 isoform X1. (1137 aa)
GDF5Growth/differentiation factor 5. (499 aa)
MOB1BMOB kinase activator 1B. (266 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
MOB1AMOB kinase activator 1A isoform X1. (216 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (557 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (386 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (581 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
WNT3Wingless-type MMTV integration site family, member 3. (170 aa)
LATS1Serine/threonine-protein kinase LATS1 isoform X1. (1127 aa)
LOC112908263Bone morphogenetic protein 8B-like. (255 aa)
CSNK1DCasein kinase I isoform X1. (412 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
TGFB3Transforming growth factor beta-3. (412 aa)
SOX2Transcription factor SOX-2. (307 aa)
AXIN2Axin-2 isoform X1. (842 aa)
LIMD1LIM domain-containing protein 1. (657 aa)
DLG3Disks large homolog 3 isoform X2; Belongs to the MAGUK family. (835 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
LATS2Non-specific serine/threonine protein kinase. (1085 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
ID2DNA-binding protein inhibitor ID-2. (196 aa)
DLG1Disks large homolog 1 isoform X3; Belongs to the MAGUK family. (1043 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
YAP1Transcriptional coactivator YAP1. (431 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (604 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (459 aa)
AMOTAngiomotin isoform X1. (1080 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
WWTR1WW domain-containing transcription regulator protein 1. (360 aa)
LLGL2Lethal(2) giant larvae protein homolog 2. (1082 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
STK3Serine/threonine-protein kinase 3. (508 aa)
APCAdenomatous polyposis coli protein isoform X1. (2862 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (513 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
YWHAZ14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (255 aa)
AXIN1Axin-1 isoform X1. (880 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa)
SMAD7Mothers against decapentaplegic homolog. (429 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
AREGAmphiregulin. (253 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
RASSF6Ras association domain-containing protein 6. (327 aa)
LOC112909244Alpha-fetoprotein-like isoform X2. (614 aa)
AFPAlpha-fetoprotein. (614 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
WTIPWilms tumor protein 1-interacting protein isoform X1. (130 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (524 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
DLG2-2Disks large homolog 2 isoform X1. (103 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (325 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (505 aa)
GLI2Zinc finger protein GLI2. (153 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
PARD6GPartitioning defective 6 homolog gamma. (384 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa)
NKD1Protein naked cuticle homolog 1. (447 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
AJUBALIM domain-containing protein ajuba isoform X1. (548 aa)
CTNNA1Catenin alpha-1. (906 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (512 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FRMD1FERM domain-containing protein 1. (463 aa)
YWHAE14-3-3 protein epsilon isoform X3; Belongs to the 14-3-3 family. (244 aa)
NKD2Protein naked cuticle homolog 2. (424 aa)
PARD6BPartitioning defective 6 homolog beta. (364 aa)
SCRIBProtein scribble homolog. (1517 aa)
LOC112908688Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (458 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
BBC3LOW QUALITY PROTEIN: bcl-2-binding component 3. (255 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (459 aa)
YWHAG14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
ITGB2Integrin beta. (743 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (411 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X4. (473 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1825 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
TEAD3Transcriptional enhancer factor TEF-5. (311 aa)
PATJinaD-like protein isoform X1. (1144 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (401 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (698 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X4. (732 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
RASSF1Ras association domain-containing protein 1 isoform X1. (344 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (269 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (409 aa)
FRMD6FERM domain-containing protein 6 isoform X2. (614 aa)
SAV1Protein salvador homolog 1. (351 aa)
LLGL1Lethal(2) giant larvae protein homolog 1. (1188 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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