STRINGSTRING
ONECUT1 ONECUT1 KAT6A KAT6A FZD8 FZD8 WNT10A WNT10A WNT6 WNT6 SKIL SKIL FGFR4 FGFR4 PCGF2 PCGF2 LIFR LIFR ESRRB ESRRB FZD3 FZD3 HOXB1 HOXB1 LIF LIF JARID2 JARID2 ESX1 ESX1 DVL1 DVL1 PCGF6 PCGF6 PCGF1 PCGF1 HAND1 HAND1 PIK3CA PIK3CA WNT9B WNT9B WNT3 WNT3 CTNNB1 CTNNB1 AKT2 AKT2 ACVR2B ACVR2B REST REST INHBA INHBA PIK3R1 PIK3R1 SOX2 SOX2 AXIN2 AXIN2 LOC112914774 LOC112914774 JAK2 JAK2 SMARCAD1 SMARCAD1 BMPR1B BMPR1B LHX5 LHX5 MAP2K2 MAP2K2 ID1 ID1 ID2 ID2 SMAD1 SMAD1 NRAS NRAS JAK3 JAK3 WNT2 WNT2 BMI1 BMI1 NANOG NANOG ACVR2A ACVR2A POU5F1 POU5F1 GRB2 GRB2 SETDB1 SETDB1 FZD5 FZD5 OTX1 OTX1 RIF1 RIF1 APC APC TBX3 TBX3 PCGF3 PCGF3 AXIN1 AXIN1 FGF2 FGF2 FZD1 FZD1 JAK1 JAK1 IGF1R IGF1R SMAD4 SMAD4 SMAD3 SMAD3 WNT8A WNT8A RAF1 RAF1 DLX5 DLX5 WNT2B WNT2B PAX6 PAX6 FZD6 FZD6 MYC MYC HRAS HRAS WNT16 WNT16 ZFHX3 ZFHX3 SMAD5 SMAD5 NEUROG1 NEUROG1 IGF1 IGF1 INHBE INHBE INHBC INHBC FZD2 FZD2 WNT7A WNT7A BMPR2 BMPR2 FZD7 FZD7 FZD4 FZD4 WNT10B WNT10B WNT1 WNT1 FGFR1 FGFR1 MAPK1 MAPK1 ACVR1 ACVR1 ACVR1C ACVR1C HESX1 HESX1 WNT5A WNT5A ZIC3 ZIC3 IL6ST IL6ST NODAL NODAL PCGF5 PCGF5 LOC112908653 LOC112908653 FGFR3 FGFR3 STAT3 STAT3 WNT11 WNT11 FZD9 FZD9 HOXA1 HOXA1 WNT7B WNT7B WNT8B WNT8B ISL1 ISL1 MAPK12 MAPK12 MAPK11 MAPK11 FZD10 FZD10 MAPK3 MAPK3 MAPK14 MAPK14 MAPK13 MAPK13 AKT3 AKT3 PIK3CB PIK3CB SMAD9 SMAD9 ID3 ID3 MEIS1 MEIS1 DVL2 DVL2 SMAD2 SMAD2 BMP4 BMP4 DUSP9 DUSP9 WNT4 WNT4 KRAS KRAS WNT3A WNT3A WNT9A WNT9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ONECUT1One cut domain family member. (472 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2026 aa)
FZD8LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (632 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
SKILSki-like protein. (685 aa)
FGFR4Fibroblast growth factor receptor. (844 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (344 aa)
LIFRLeukemia inhibitory factor receptor. (1148 aa)
ESRRBSteroid hormone receptor ERR2. (491 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
HOXB1Homeobox protein Hox-B1. (302 aa)
LIFLeukemia inhibitory factor. (375 aa)
JARID2Protein Jumonji. (1162 aa)
ESX1Homeobox protein ESX1. (264 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
PCGF6Polycomb group RING finger protein 6 isoform X1. (349 aa)
PCGF1Polycomb group RING finger protein 1 isoform X2. (259 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
WNT3Wingless-type MMTV integration site family, member 3. (170 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
AKT2RAC-beta serine/threonine-protein kinase. (557 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
RESTRE1-silencing transcription factor. (996 aa)
INHBAInhibin beta A chain. (424 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
SOX2Transcription factor SOX-2. (307 aa)
AXIN2Axin-2 isoform X1. (842 aa)
LOC112914774Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
SMARCAD1annotation not available (1026 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
LHX5LIM/homeobox protein Lhx5. (417 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (398 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
ID2DNA-binding protein inhibitor ID-2. (196 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
NRASGTPase NRas. (189 aa)
JAK3Tyrosine-protein kinase. (1106 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
NANOGHomeobox protein NANOG isoform X1. (307 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
POU5F1POU domain protein. (360 aa)
GRB2Growth factor receptor-bound protein 2. (351 aa)
SETDB1Histone-lysine N-methyltransferase SETDB1 isoform X1. (1294 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
OTX1Homeobox protein OTX1. (354 aa)
RIF1Telomere-associated protein RIF1 isoform X1. (2447 aa)
APCAdenomatous polyposis coli protein isoform X1. (2862 aa)
TBX3T-box transcription factor TBX3 isoform X1. (737 aa)
PCGF3Polycomb group RING finger protein 3 isoform X1. (331 aa)
AXIN1Axin-1 isoform X1. (880 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
IGF1RTyrosine-protein kinase receptor. (1249 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
DLX5Homeobox protein DLX-5. (289 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
PAX6Paired box protein Pax-6 isoform X2. (422 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (524 aa)
HRASGTPase HRas isoform X1. (189 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
ZFHX3Zinc finger homeobox protein 3. (3725 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
NEUROG1Neurogenin-1. (247 aa)
IGF1Insulin-like growth factor I isoform X1. (187 aa)
INHBEInhibin beta E chain. (324 aa)
INHBCInhibin beta C chain. (351 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (505 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (610 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (363 aa)
HESX1Homeobox expressed in ES cells 1. (189 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ZIC3Zinc finger protein ZIC 3 isoform X1. (466 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (831 aa)
NODALNodal homolog isoform X1. (348 aa)
PCGF5Polycomb group RING finger protein 5 isoform X1. (256 aa)
LOC112908653Double homeobox protein 4-like protein 2. (356 aa)
FGFR3Fibroblast growth factor receptor. (876 aa)
STAT3Signal transducer and activator of transcription. (791 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa)
HOXA1Homeobox protein Hox-A1. (333 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (411 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
ISL1Insulin gene enhancer protein ISL-1. (356 aa)
MAPK12Mitogen-activated protein kinase. (348 aa)
MAPK11Mitogen-activated protein kinase. (332 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (413 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
SMAD9Mothers against decapentaplegic homolog. (469 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
MEIS1Homeobox protein Meis1 isoform X1. (452 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X4. (732 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (409 aa)
DUSP9Dual specificity protein phosphatase 9. (416 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
KRASGTPase KRas isoform X1. (418 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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