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GNB5 GNB5 LOC112927180 LOC112927180 GNAQ GNAQ GNAI3 GNAI3 GNG8 GNG8 CALM3 CALM3 GNG7 GNG7 GNGT2 GNGT2 ADCY5 ADCY5 PRKG1 PRKG1 ADCYAP1 ADCYAP1 GRIN2B GRIN2B GNB1 GNB1 GNB4 GNB4 GRIA1 GRIA1 PRKCB PRKCB FOS FOS PRKCA PRKCA CALML5 CALML5 CAMK2A CAMK2A CAMK2D CAMK2D GNG12 GNG12 PRKCG PRKCG GNG4 GNG4 LOC112914300 LOC112914300 GRIN2C GRIN2C CACNA1G CACNA1G GNB3 GNB3 GNG13 GNG13 CREB1 CREB1 RYR1 RYR1 MTNR1A MTNR1A ITPR1-2 ITPR1-2 NOS1 NOS1 RYR2 RYR2 CACNA1I CACNA1I GRIA4 GRIA4 GUCY1A2 GUCY1A2 CALML4 CALML4 ADCY3 ADCY3 GNGT1 GNGT1 KCNJ9 KCNJ9 ADCY9 ADCY9 LOC112932168 LOC112932168 LOC112932169 LOC112932169 ADCY8 ADCY8 ADCY2 ADCY2 GRIN2A GRIN2A RPS6KA5 RPS6KA5 GNAI1 GNAI1 ADCY6 ADCY6 MAPK1 MAPK1 KCNJ3 KCNJ3 GRIA2 GRIA2 ADCYAP1R1 ADCYAP1R1 GNAO1 GNAO1 PLCB4 PLCB4 CACNA1D CACNA1D PER2 PER2 CAMK2G CAMK2G GRIN2D GRIN2D PLCB1 PLCB1 GNB2 GNB2 GNG14 GNG14 PRKG2 PRKG2 GUCY1B1 GUCY1B1 GUCY1A1 GUCY1A1 KCNJ6 KCNJ6 MAPK3 MAPK3 RYR3 RYR3 ADCY10 ADCY10 PER3 PER3 PLCB2 PLCB2 PRKACA PRKACA PER1 PER1 GRIA3 GRIA3 GNAI2 GNAI2 ADCY4 ADCY4 GRIN1 GRIN1 GNG2 GNG2 PLCB3 PLCB3 GNG3 GNG3 PRKACB PRKACB RASD1 RASD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNB5Guanine nucleotide-binding protein subunit beta-5. (342 aa)
LOC112927180Calmodulin-alpha-like. (81 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CALM3Calmodulin-1; Belongs to the calmodulin family. (149 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
PRKG1cGMP-dependent protein kinase. (568 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (170 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1513 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GRIA1Glutamate receptor 1. (899 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
FOSProto-oncogene c-Fos. (380 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
CALML5Calmodulin-like protein 5. (149 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2; Belongs to the protein kinase superfamily. (478 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X6. (533 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (105 aa)
LOC112914300Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like isoform X1. (675 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C. (1187 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2379 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (270 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
RYR1LOW QUALITY PROTEIN: ryanodine receptor 1. (4780 aa)
MTNR1AMelatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (316 aa)
ITPR1-2Inositol 1,4,5-trisphosphate receptor type 1. (1018 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
RYR2Ryanodine receptor 2. (4919 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2127 aa)
GRIA4Glutamate receptor 4 isoform X3. (884 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (694 aa)
CALML4Calmodulin-like protein 4. (273 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1314 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (354 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC112932168Guanine nucleotide-binding protein G(S) subunit alpha isoform X6. (394 aa)
LOC112932169Neuroendocrine secretory protein 55. (247 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1051 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1457 aa)
RPS6KA5Ribosomal protein S6 kinase. (913 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X2. (377 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
GRIA2Glutamate receptor 2 isoform X1. (883 aa)
ADCYAP1R1Pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (498 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (301 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2167 aa)
PER2Period circadian protein homolog 2 isoform X1. (1109 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (611 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (917 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (372 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (641 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (423 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
RYR3Ryanodine receptor 3. (4847 aa)
ADCY10Adenylate cyclase type 10. (1610 aa)
PER3Period circadian protein homolog 3 isoform X2. (1130 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
PER1Period circadian protein homolog 1. (1294 aa)
GRIA3Glutamate receptor 3 isoform X2. (894 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (987 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (103 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
RASD1Dexamethasone-induced Ras-related protein 1 isoform X1. (279 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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