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GNB5 GNB5 GNAQ GNAQ NDUFA5 NDUFA5 NDUFB2 NDUFB2 LOC112930992 LOC112930992 NDUFA6 NDUFA6 GNAI3 GNAI3 GABRP GABRP GNG8 GNG8 GNG7 GNG7 CACNA1S CACNA1S GNGT2 GNGT2 GABRG2 GABRG2 GABRA1 GABRA1 GABRA6 GABRA6 ADCY5 ADCY5 GNB1 GNB1 GNB4 GNB4 DAGLA DAGLA NDUFB5 NDUFB5 GRM1 GRM1 GRIA1 GRIA1 PRKCB PRKCB NDUFAB1 NDUFAB1 PRKCA PRKCA FAAH FAAH NDUFA3 NDUFA3 GNG12 GNG12 PRKCG PRKCG GABRG3 GABRG3 GABRA5 GABRA5 GABRB3 GABRB3 GNG4 GNG4 NDUFA8 NDUFA8 NDUFB10 NDUFB10 SLC17A6 SLC17A6 CNR1 CNR1 GABRR1 GABRR1 NDUFV1 NDUFV1 GABRR2 GABRR2 GNB3 GNB3 GNG13 GNG13 NDUFV2 NDUFV2 LOC112926594 LOC112926594 PTGS2 PTGS2 ITPR1-2 ITPR1-2 NDUFA2 NDUFA2 MAPK10 MAPK10 GRIA4 GRIA4 NDUFB11 NDUFB11 LOC112921738 LOC112921738 ADCY3 ADCY3 GNGT1 GNGT1 DAGLB DAGLB NDUFS2 NDUFS2 NDUFA4 NDUFA4 ABHD6 ABHD6 KCNJ9 KCNJ9 ADCY9 ADCY9 NDUFB9 NDUFB9 NDUFS1 NDUFS1 ADCY8 ADCY8 ADCY2 ADCY2 NDUFA9 NDUFA9 MGLL MGLL SLC17A8 SLC17A8 GRM5 GRM5 NDUFB3 NDUFB3 NDUFA12 NDUFA12 GNAI1 GNAI1 ADCY6 ADCY6 MAPK1 MAPK1 KCNJ3 KCNJ3 MAPK8 MAPK8 GRIA2 GRIA2 GNAO1 GNAO1 NDUFB4 NDUFB4 NDUFS6 NDUFS6 SLC17A7 SLC17A7 NDUFS7 NDUFS7 NDUFC2 NDUFC2 NDUFS5 NDUFS5 PLCB4 PLCB4 NDUFA10 NDUFA10 CACNA1D CACNA1D GABRG1 GABRG1 GABRA4 GABRA4 PLCB1 PLCB1 NDUFS3 NDUFS3 GNB2 GNB2 GABRB1 GABRB1 GNG14 GNG14 NDUFA7 NDUFA7 KCNJ6 KCNJ6 MAPK12 MAPK12 MAPK11 MAPK11 NDUFS4 NDUFS4 NDUFS8 NDUFS8 MAPK3 MAPK3 MAPK14 MAPK14 MAPK13 MAPK13 PLCB2 PLCB2 CACNA1A-2 CACNA1A-2 PRKACA PRKACA NDUFA11 NDUFA11 MAPK9 MAPK9 NDUFB7 NDUFB7 GRIA3 GRIA3 CACNA1B CACNA1B GNAI2 GNAI2 GABRE GABRE GABRA3 GABRA3 GABRQ GABRQ ADCY4 ADCY4 SLC32A1 SLC32A1 GNG2 GNG2 PLCB3 PLCB3 GNG3 GNG3 PRKACB PRKACB ITPR2 ITPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GNB5Guanine nucleotide-binding protein subunit beta-5. (342 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa)
NDUFB2NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (85 aa)
LOC112930992NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (70 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (147 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GABRPGamma-aminobutyric acid receptor subunit pi isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1865 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GABRG2Gamma-aminobutyric acid receptor subunit gamma-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
GABRA1Gamma-aminobutyric acid receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GABRA6Gamma-aminobutyric acid receptor subunit alpha-6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
DAGLASn1-specific diacylglycerol lipase alpha. (1042 aa)
NDUFB5NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial. (250 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1190 aa)
GRIA1Glutamate receptor 1. (899 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
FAAHFatty-acid amide hydrolase 1. (525 aa)
NDUFA3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. (84 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GABRG3Gamma-aminobutyric acid receptor subunit gamma-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (316 aa)
GABRA5Gamma-aminobutyric acid receptor subunit alpha-5 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (447 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (105 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8. (207 aa)
NDUFB10NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (205 aa)
SLC17A6Vesicular glutamate transporter 2 isoform X1. (582 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
GABRR1Gamma-aminobutyric acid receptor subunit rho-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
GABRR2Gamma-aminobutyric acid receptor subunit rho-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (490 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (270 aa)
NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (249 aa)
LOC112926594Cytochrome c oxidase subunit NDUFA4. (82 aa)
PTGS2Prostaglandin G/H synthase 2. (605 aa)
ITPR1-2Inositol 1,4,5-trisphosphate receptor type 1. (1018 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
MAPK10Mitogen-activated protein kinase. (529 aa)
GRIA4Glutamate receptor 4 isoform X3. (884 aa)
NDUFB11NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (154 aa)
LOC112921738NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1. (57 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1314 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
DAGLBSn1-specific diacylglycerol lipase beta isoform X1. (671 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (816 aa)
NDUFA4Cytochrome c oxidase subunit NDUFA4. (143 aa)
ABHD6Monoacylglycerol lipase ABHD6. (337 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (354 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
NDUFB9NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family. (197 aa)
NDUFS1NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1051 aa)
NDUFA9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (377 aa)
MGLLMonoglyceride lipase. (348 aa)
SLC17A8Vesicular glutamate transporter 3. (588 aa)
GRM5LOW QUALITY PROTEIN: metabotropic glutamate receptor 5. (1145 aa)
NDUFB3NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (98 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X2. (377 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
MAPK8Mitogen-activated protein kinase. (387 aa)
GRIA2Glutamate receptor 2 isoform X1. (883 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (301 aa)
NDUFB4NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
SLC17A7Vesicular glutamate transporter 1. (560 aa)
NDUFS7NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Belongs to the complex I 20 kDa subunit family. (262 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
NDUFS5NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (106 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (376 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2167 aa)
GABRG1Gamma-aminobutyric acid receptor subunit gamma-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (468 aa)
GABRA4Gamma-aminobutyric acid receptor subunit alpha-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (562 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (263 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (372 aa)
GABRB1Gamma-aminobutyric acid receptor subunit beta-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (466 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
NDUFA7NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (423 aa)
MAPK12Mitogen-activated protein kinase. (348 aa)
MAPK11Mitogen-activated protein kinase. (332 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (186 aa)
NDUFS8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X3. (210 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (413 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
CACNA1A-2Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (296 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
NDUFA11NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (141 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
NDUFB7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (137 aa)
GRIA3Glutamate receptor 3 isoform X2. (894 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2243 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
GABREGamma-aminobutyric acid receptor subunit epsilon; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
GABRA3Gamma-aminobutyric acid receptor subunit alpha-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (524 aa)
GABRQGamma-aminobutyric acid receptor subunit theta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (710 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
SLC32A1Vesicular inhibitory amino acid transporter. (526 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (103 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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