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GNB5 GNB5 PLA2G4D PLA2G4D SLC1A7 SLC1A7 PLA2G4F PLA2G4F GRM6 GRM6 GRM3 GRM3 PLD1 PLD1 GNAQ GNAQ GNAI3 GNAI3 GNG8 GNG8 GNG7 GNG7 GNGT2 GNGT2 ADCY5 ADCY5 SHANK2 SHANK2 GRIN2B GRIN2B GNB1 GNB1 GNB4 GNB4 GRM1 GRM1 HOMER2 HOMER2 PPP3CC PPP3CC GRIA1 GRIA1 PRKCB PRKCB PRKCA PRKCA GRM8 GRM8 SLC1A2 SLC1A2 SLC1A1 SLC1A1 HOMER3 HOMER3 GNG12 GNG12 PRKCG PRKCG GLUL GLUL PPP3CA PPP3CA GNG4 GNG4 LOC112913297 LOC112913297 SLC17A6 SLC17A6 DLGAP1 DLGAP1 GRIN2C GRIN2C GRK2 GRK2 GRIK5 GRIK5 SLC1A3 SLC1A3 GNB3 GNB3 GNG13 GNG13 PLA2G4A PLA2G4A ITPR1-2 ITPR1-2 GRIA4 GRIA4 ADCY3 ADCY3 GRIK2 GRIK2 GNGT1 GNGT1 GRK3 GRK3 ADCY9 ADCY9 LOC112932168 LOC112932168 LOC112932169 LOC112932169 ADCY8 ADCY8 SLC38A1 SLC38A1 SLC38A2 SLC38A2 ADCY2 ADCY2 GRIN2A GRIN2A SLC17A8 SLC17A8 GRM5 GRM5 GRIN3A GRIN3A PPP3R2 PPP3R2 GNAI1 GNAI1 ADCY6 ADCY6 GRIK1 GRIK1 MAPK1 MAPK1 KCNJ3 KCNJ3 GRIK4 GRIK4 GRIA2 GRIA2 SLC1A6 SLC1A6 TRPC1 TRPC1 GNAO1 GNAO1 SLC17A7 SLC17A7 PLCB4 PLCB4 PPP3CB PPP3CB CACNA1D CACNA1D GRIK3 GRIK3 GRIN2D GRIN2D PLCB1 PLCB1 GNB2 GNB2 GNG14 GNG14 HOMER1 HOMER1 GRM7 GRM7 MAPK3 MAPK3 GRM4 GRM4 PLCB2 PLCB2 CACNA1A-2 CACNA1A-2 PRKACA PRKACA GRM2 GRM2 PLA2G4B PLA2G4B PLA2G4E PLA2G4E GLS GLS PLD2 PLD2 PPP3R1 PPP3R1 GRIA3 GRIA3 GNAI2 GNAI2 SLC38A3 SLC38A3 ADCY4 ADCY4 GRIN1 GRIN1 GNG2 GNG2 PLCB3 PLCB3 GNG3 GNG3 PRKACB PRKACB ITPR2 ITPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNB5Guanine nucleotide-binding protein subunit beta-5. (342 aa)
PLA2G4DPhospholipase A2. (769 aa)
SLC1A7Amino acid transporter. (574 aa)
PLA2G4FPhospholipase A2. (863 aa)
GRM6Metabotropic glutamate receptor 6. (865 aa)
GRM3Metabotropic glutamate receptor 3. (879 aa)
PLD1Phospholipase. (1075 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2. (1828 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1513 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1190 aa)
HOMER2Homer protein homolog 2. (370 aa)
PPP3CCSerine/threonine-protein phosphatase. (682 aa)
GRIA1Glutamate receptor 1. (899 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
GRM8Metabotropic glutamate receptor 8. (927 aa)
SLC1A2Amino acid transporter. (607 aa)
SLC1A1Amino acid transporter. (568 aa)
HOMER3Homer protein homolog 3 isoform X1. (360 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GLULGlutamine synthetase. (508 aa)
PPP3CASerine/threonine-protein phosphatase. (572 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (105 aa)
LOC112913297Metabotropic glutamate receptor 7-like. (189 aa)
SLC17A6Vesicular glutamate transporter 2 isoform X1. (582 aa)
DLGAP1Disks large-associated protein 1. (1060 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C. (1187 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
GRIK5Glutamate receptor ionotropic, kainate 5 isoform X2. (884 aa)
SLC1A3Amino acid transporter. (542 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (270 aa)
PLA2G4APhospholipase A2. (749 aa)
ITPR1-2Inositol 1,4,5-trisphosphate receptor type 1. (1018 aa)
GRIA4Glutamate receptor 4 isoform X3. (884 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1314 aa)
GRIK2Glutamate receptor ionotropic, kainate 2 isoform X1. (859 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (672 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
LOC112932168Guanine nucleotide-binding protein G(S) subunit alpha isoform X6. (394 aa)
LOC112932169Neuroendocrine secretory protein 55. (247 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
SLC38A1Sodium-coupled neutral amino acid transporter 1. (487 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2 isoform X1. (570 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1051 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1457 aa)
SLC17A8Vesicular glutamate transporter 3. (588 aa)
GRM5LOW QUALITY PROTEIN: metabotropic glutamate receptor 5. (1145 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A isoform X1. (243 aa)
PPP3R2Calcineurin subunit B type 2. (252 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X2. (377 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
GRIK1Glutamate receptor ionotropic, kainate 1 isoform X1. (925 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
GRIK4Glutamate receptor ionotropic, kainate 4 isoform X1. (1013 aa)
GRIA2Glutamate receptor 2 isoform X1. (883 aa)
SLC1A6Amino acid transporter. (564 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (301 aa)
SLC17A7Vesicular glutamate transporter 1. (560 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PPP3CBSerine/threonine-protein phosphatase. (529 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2167 aa)
GRIK3Glutamate receptor ionotropic, kainate 3. (919 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (917 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (372 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
HOMER1Homer protein homolog 1 isoform X1. (376 aa)
GRM7Metabotropic glutamate receptor 7. (550 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
GRM4Metabotropic glutamate receptor 4 isoform X1. (914 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
CACNA1A-2Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (296 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
GRM2Metabotropic glutamate receptor 2 isoform X1. (884 aa)
PLA2G4BPhospholipase A2. (769 aa)
PLA2G4EPhospholipase A2. (823 aa)
GLSGlutaminase kidney isoform, mitochondrial. (599 aa)
PLD2Phospholipase. (522 aa)
PPP3R1Calcineurin subunit B type 1. (192 aa)
GRIA3Glutamate receptor 3 isoform X2. (894 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3. (520 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (987 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (103 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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