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| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (782 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | PPP2R2C | Protein phosphatase 2, regulatory subunit B, gamma isoform X1. (405 aa) |
| | IFNB1 | Interferon beta. (186 aa) |
| | LOC112921945 | Interferon alpha-2-like. (173 aa) |
| | LOC112921941 | Interferon alpha-1/2-like. (187 aa) |
| | LOC112921942 | Interferon alpha-1/2-like. (187 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf isoform X1. (765 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (470 aa) |
| | E2F3 | Transcription factor E2F3. (224 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (386 aa) |
| | E2F1 | Transcription factor E2F1. (390 aa) |
| | CTNNB1 | Catenin beta-1 isoform X1. (781 aa) |
| | AKT2 | RAC-beta serine/threonine-protein kinase. (557 aa) |
| | CLDN18 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (560 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | LOC112914774 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | LOC112911647-2 | Interferon alpha-1/2-like. (187 aa) |
| | LOC112911646 | Interferon alpha-1/2. (187 aa) |
| | LOC112911635 | Interferon alpha-1/2-like. (187 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2. (398 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain-containing protein 2. (361 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (245 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | RNASEL | 2-5A-dependent ribonuclease isoform X1. (724 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (246 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1154 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthase 3. (1087 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthase 1. (399 aa) |
| | LOC112912456 | Interferon-induced protein with tetratricopeptide repeats 1-like. (480 aa) |
| | LOC112912454 | LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like. (451 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (313 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (351 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (359 aa) |
| | TLR3 | Toll-like receptor 3 isoform X2; Belongs to the Toll-like receptor family. (902 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (355 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (255 aa) |
| | CLDN24 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (765 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (288 aa) |
| | PIAS1 | E3 SUMO-protein ligase PIAS1 isoform X1. (655 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (820 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1. (630 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (227 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (463 aa) |
| | CLDN25 | Putative claudin-25. (228 aa) |
| | MX2 | Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (262 aa) |
| | MX1-2 | Interferon-induced GTP-binding protein Mx1. (156 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (524 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (457 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | IRF7 | Interferon regulatory factor 7. (90 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform X2. (625 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1211 aa) |
| | LDLR | Low-density lipoprotein receptor. (866 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1250 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (533 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (509 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1. (732 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (279 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (327 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (392 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (256 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | DDX58 | Probable ATP-dependent RNA helicase DDX58. (875 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (512 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | YWHAE | 14-3-3 protein epsilon isoform X3; Belongs to the 14-3-3 family. (244 aa) |
| | STAT2 | Signal transducer and activator of transcription. (855 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (428 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (290 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6. (324 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1. (569 aa) |
| | BAX | Apoptosis regulator BAX isoform X2. (192 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (521 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa) |
| | STAT3 | Signal transducer and activator of transcription. (791 aa) |
| | YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | PSME3 | Proteasome activator complex subunit 3. (247 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein. (520 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | CLDN4 | Claudin-4-like. (210 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha isoform X1. (468 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X2. (211 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (486 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa) |
| | NR1H3 | Oxysterols receptor LXR-alpha. (447 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | EIF2AK4 | eIF-2-alpha kinase GCN2 isoform X1. (1654 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | E2F2 | Transcription factor E2F2. (447 aa) |
| | RELA | Transcription factor p65 isoform X2. (542 aa) |
| | RXRA | Retinoic acid receptor RXR-alpha isoform X1. (568 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | RB1 | Retinoblastoma-associated protein. (928 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (1113 aa) |
| | CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (495 aa) |
| | YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (269 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (419 aa) |
| | BAD | Bcl2-associated agonist of cell death. (157 aa) |
| | SOS2 | Son of sevenless homolog 2. (1308 aa) |
| | KRAS | GTPase KRas isoform X1. (418 aa) |
