STRINGSTRING
TRAF3 TRAF3 HEY1 HEY1 MPP5 MPP5 IKBKB IKBKB ATP6V1D ATP6V1D FZD8 FZD8 WNT10A WNT10A WNT6 WNT6 PARD3 PARD3 PRKCI PRKCI PPP2R2C PPP2R2C RFNG RFNG LAMA2 LAMA2 ITGB1 ITGB1 IFNB1 IFNB1 LOC112921945 LOC112921945 LOC112921941 LOC112921941 ATP6V1C2 ATP6V1C2 LOC112921942 LOC112921942 MAML1 MAML1 ATP6V0D2 ATP6V0D2 COL6A3-2 COL6A3-2 PTGER4 PTGER4 PPP2R2D PPP2R2D ATP6V0E1 ATP6V0E1 TCF7L1 TCF7L1 LOC112912180 LOC112912180 ATP6V0A4 ATP6V0A4 CCNE2 CCNE2 FZD3 FZD3 LAMA3 LAMA3 PPP2R2A PPP2R2A THBS3 THBS3 ISG15 ISG15 ATP6V1G1 ATP6V1G1 ITGA3 ITGA3 DVL1 DVL1 PSEN1 PSEN1 COL1A1 COL1A1 PRKCZ PRKCZ CDKN1B CDKN1B PIK3CA PIK3CA CCND1 CCND1 E2F1 E2F1 CHAD CHAD COL9A2 COL9A2 WNT9B WNT9B WNT3 WNT3 HEYL HEYL CTNNB1 CTNNB1 ITGB3 ITGB3 LFNG LFNG ATP6V1E2 ATP6V1E2 AKT2 AKT2 PPP2R3A PPP2R3A ITGA9 ITGA9 PIK3R1 PIK3R1 LAMA4 LAMA4 HDAC2 HDAC2 EP300 EP300 AXIN2 AXIN2 TBP TBP DLG3 DLG3 CREB3L2 CREB3L2 ITGB5 ITGB5 LOC112914774 LOC112914774 PDGFRB PDGFRB ITGA10 ITGA10 RHEB RHEB COMP COMP PPP2R5A PPP2R5A ATP6V0B ATP6V0B LOC112911647-2 LOC112911647-2 LOC112911646 LOC112911646 LOC112911635 LOC112911635 MAP2K2 MAP2K2 PPP2R3B PPP2R3B CREB3L3 CREB3L3 ITGB8 ITGB8 DLG1 DLG1 ITGAV ITGAV LAMC1 LAMC1 LAMC2 LAMC2 FN1 FN1 ATP6V0C ATP6V0C NFKB1 NFKB1 SPP1 SPP1 IBSP IBSP ATP6V0E2 ATP6V0E2 UBE3A UBE3A COL9A1 COL9A1 LAMB3 LAMB3 EGFR EGFR NRAS NRAS SLC9A3R1 SLC9A3R1 TCIRG1 TCIRG1 MDM2 MDM2 COL4A6 COL4A6 RPS6KB2 RPS6KB2 WNT2 WNT2 ATP6V1F ATP6V1F COL4A5 COL4A5 PPP2R1A PPP2R1A TRADD TRADD TNC TNC GRB2 GRB2 CHD4 CHD4 LLGL2 LLGL2 LAMA1 LAMA1 MAML2 MAML2 FZD5 FZD5 CREB1 CREB1 TNFRSF1A TNFRSF1A ATP6V0D1 ATP6V0D1 PTGS2 PTGS2 APC APC PARD6A PARD6A TLR3 TLR3 CASP3 CASP3 CCNA2 CCNA2 AXIN1 AXIN1 ATP6V1G1-2 ATP6V1G1-2 IKBKE IKBKE ENSVVUP00000018614 ENSVVUP00000018614 FZD1 FZD1 RBPJ RBPJ JAK1 JAK1 TNR TNR CSNK1A1 CSNK1A1 FASLG FASLG RELN RELN MAGI1 MAGI1 ITGB4 ITGB4 PTK2 PTK2 ITGA11 ITGA11 WNT8A WNT8A TBK1 TBK1 LOC112913727 LOC112913727 RAF1 RAF1 ATM ATM CDK6 CDK6 COL9A3 COL9A3 HDAC1 HDAC1 ITGA6 ITGA6 COL1A2 COL1A2 JAG1 JAG1 WNT2B WNT2B CREBBP CREBBP MX2 MX2 MX1-2 MX1-2 VTN VTN ITGA4 ITGA4 ATP6V1C1 ATP6V1C1 CDK4 CDK4 LOC112932168 LOC112932168 FZD6 FZD6 CCNE1 CCNE1 LOC112932169 LOC112932169 VWF VWF HRAS HRAS WNT16 WNT16 LAMB4 LAMB4 DLG2-2 DLG2-2 EGF EGF ATP6V1H ATP6V1H FZD2 FZD2 COL2A1 COL2A1 CCND2 CCND2 RPS6KB1 RPS6KB1 WNT7A WNT7A PSMC1 PSMC1 PKM PKM FZD7 FZD7 FZD4 FZD4 SOS1 SOS1 RBPJL RBPJL EIF2AK2 EIF2AK2 PARD6G PARD6G TBPL1 TBPL1 ITGB6 ITGB6 LOC112913586 LOC112913586 RBL2 RBL2 WNT10B WNT10B WNT1 WNT1 PPP2CB PPP2CB PPP2R3C PPP2R3C EIF4EBP1 EIF4EBP1 MAPK1 MAPK1 ATP6V1G2 ATP6V1G2 TNF TNF LAMB1 LAMB1 COL4A1 COL4A1 WNT5A WNT5A NFX1 NFX1 PPP2R2B PPP2R2B NOTCH3 NOTCH3 PPP2CA PPP2CA OASL OASL LOC112932874 LOC112932874 STAT2 STAT2 ATP6V1A ATP6V1A CDK2 CDK2 TERT TERT IRF3 IRF3 ATP6V1E1 ATP6V1E1 PARD6B PARD6B SCRIB SCRIB FAS FAS IFNAR1 IFNAR1 BAX BAX IFNAR2 IFNAR2 MFNG MFNG TADA3-2 TADA3-2 ATP6V0A1 ATP6V0A1 ITGA7 ITGA7 TUBG1-2 TUBG1-2 COL6A2 COL6A2 WNT11 WNT11 ATR ATR IRF1 IRF1 FZD9 FZD9 CREB5 CREB5 CHUK CHUK WNT7B WNT7B WNT8B WNT8B THBS4 THBS4 GPSM3 GPSM3 HES1 HES1 ITGA1 ITGA1 BAK1 BAK1 ITGA2 ITGA2 FZD10 FZD10 COL4A3 COL4A3 COL4A4 COL4A4 MAPK3 MAPK3 ATP6V1B2 ATP6V1B2 CDKN1A CDKN1A HES2 HES2 THBS1 THBS1 HES3 HES3 STAT1 STAT1 PATJ PATJ AKT3 AKT3 PIK3CB PIK3CB CCNA1 CCNA1 CCND3 CCND3 FOXO1 FOXO1 PRKACA PRKACA CREB3L1 CREB3L1 RELA RELA HES5 HES5 ATP6V0A2 ATP6V0A2 PPP2R5B PPP2R5B LAMC3 LAMC3 PPP2R5D PPP2R5D DVL2 DVL2 TP53 TP53 ITGB7 ITGB7 ATP6V1B1 ATP6V1B1 RB1 RB1 MTOR MTOR TSC1 TSC1 PPP2R5C PPP2R5C LAMB2 LAMB2 UBR4 UBR4 RBL1 RBL1 PPP2R5E PPP2R5E IKBKG IKBKG ATP6AP1 ATP6AP1 TBPL2 TBPL2 ATP6V1G3 ATP6V1G3 BCAP31 BCAP31 BAD BAD SOS2 SOS2 PRKACB PRKACB LLGL1 LLGL1 CDC42 CDC42 WNT4 WNT4 KRAS KRAS WNT3A WNT3A WNT9A WNT9A NOTCH2 NOTCH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1. (304 aa)
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (675 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (782 aa)
ATP6V1DV-type proton ATPase subunit D. (310 aa)
FZD8LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (632 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
PARD3Partitioning defective 3 homolog. (1328 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (571 aa)
PPP2R2CProtein phosphatase 2, regulatory subunit B, gamma isoform X1. (405 aa)
RFNGbeta-1,3-N-acetylglucosaminyltransferase radical fringe. (205 aa)
LAMA2Laminin subunit alpha-2. (3017 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
IFNB1Interferon beta. (186 aa)
LOC112921945Interferon alpha-2-like. (173 aa)
LOC112921941Interferon alpha-1/2-like. (187 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
LOC112921942Interferon alpha-1/2-like. (187 aa)
MAML1Mastermind-like protein 1. (1004 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
COL6A3-2Collagen alpha-3(VI) chain isoform X1. (547 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (490 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (470 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
TCF7L1Transcription factor 7-like 1. (567 aa)
LOC112912180HLA class I histocompatibility antigen, A-11 alpha chain-like isoform X1; Belongs to the MHC class I family. (449 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
CCNE2G1/S-specific cyclin-E2 isoform X2; Belongs to the cyclin family. (404 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LAMA3Laminin subunit alpha-3. (1680 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (466 aa)
THBS3Thrombospondin-3. (936 aa)
ISG15Ubiquitin-like protein ISG15. (168 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (110 aa)
ITGA3Integrin alpha-3; Belongs to the integrin alpha chain family. (970 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (466 aa)
COL1A1Collagen alpha-1(I) chain. (1288 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (557 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (386 aa)
E2F1Transcription factor E2F1. (390 aa)
CHADChondroadherin. (359 aa)
COL9A2LOW QUALITY PROTEIN: collagen alpha-2(IX) chain. (427 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
WNT3Wingless-type MMTV integration site family, member 3. (170 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein. (359 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
LFNGbeta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (246 aa)
ATP6V1E2V-type proton ATPase subunit E 2. (226 aa)
AKT2RAC-beta serine/threonine-protein kinase. (557 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1152 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (934 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LAMA4Laminin subunit alpha-4. (1767 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (516 aa)
EP300Histone acetyltransferase p300 isoform X1. (2430 aa)
AXIN2Axin-2 isoform X1. (842 aa)
TBPTATA-box-binding protein isoform X1. (324 aa)
DLG3Disks large homolog 3 isoform X2; Belongs to the MAGUK family. (835 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (838 aa)
LOC112914774Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1135 aa)
ITGA10Integrin alpha-10 isoform X1; Belongs to the integrin alpha chain family. (1165 aa)
RHEBGTP-binding protein Rheb. (168 aa)
COMPCartilage oligomeric matrix protein. (332 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (493 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
LOC112911647-2Interferon alpha-1/2-like. (187 aa)
LOC112911646Interferon alpha-1/2. (187 aa)
LOC112911635Interferon alpha-1/2-like. (187 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (398 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1. (569 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (525 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (782 aa)
DLG1Disks large homolog 1 isoform X3; Belongs to the MAGUK family. (1043 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1054 aa)
LAMC1Laminin subunit gamma-1. (1573 aa)
LAMC2Laminin subunit gamma-2 isoform X1. (1194 aa)
FN1Fibronectin. (2267 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
SPP1Osteopontin isoform X1. (303 aa)
IBSPBone sialoprotein 2. (313 aa)
ATP6V0E2V-type proton ATPase subunit e 2. (81 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
COL9A1Collagen alpha-1(IX) chain. (164 aa)
LAMB3Laminin subunit beta-3 isoform X1. (1172 aa)
EGFRReceptor protein-tyrosine kinase. (1154 aa)
NRASGTPase NRas. (189 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (350 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
MDM2E3 ubiquitin-protein ligase Mdm2. (177 aa)
COL4A6Collagen alpha-6(IV) chain isoform X1. (1554 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (589 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
COL4A5Collagen alpha-5(IV) chain isoform X2. (1484 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (313 aa)
TNCTenascin isoform X2. (2380 aa)
GRB2Growth factor receptor-bound protein 2. (351 aa)
CHD4chromodomain-helicase-DNA-binding protein 4 isoform X3. (1984 aa)
LLGL2Lethal(2) giant larvae protein homolog 2. (1082 aa)
LAMA1Laminin subunit alpha-1. (2985 aa)
MAML2Mastermind-like protein 2. (464 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (359 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
PTGS2Prostaglandin G/H synthase 2. (605 aa)
APCAdenomatous polyposis coli protein isoform X1. (2862 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (513 aa)
TLR3Toll-like receptor 3 isoform X2; Belongs to the Toll-like receptor family. (902 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (355 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (431 aa)
AXIN1Axin-1 isoform X1. (880 aa)
ATP6V1G1-2V-type H+-transporting ATPase subunit G. (108 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (765 aa)
ENSVVUP00000018614DLA class I histocompatibility antigen, A9/A9 alpha chain-like. (430 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa)
RBPJRecombining binding protein suppressor of hairless isoform X1. (513 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
TNRtenascin-R. (1356 aa)
CSNK1A1Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (384 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (288 aa)
RELNLOW QUALITY PROTEIN: reelin. (3224 aa)
MAGI1Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X5. (1415 aa)
ITGB4Integrin beta. (1805 aa)
PTK2Focal adhesion kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1059 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1123 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
TBK1Serine/threonine-protein kinase TBK1 isoform X1. (820 aa)
LOC112913727DLA class I histocompatibility antigen, A9/A9 alpha chain; Belongs to the MHC class I family. (361 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3060 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (463 aa)
COL9A3Collagen alpha-3(IX) chain isoform X1. (570 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (489 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1082 aa)
COL1A2Collagen alpha-2(I) chain. (1274 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
CREBBPCREB-binding protein isoform X1. (2442 aa)
MX2Interferon-induced GTP-binding protein Mx2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (262 aa)
MX1-2Interferon-induced GTP-binding protein Mx1. (156 aa)
VTNVitronectin. (464 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1030 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (405 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
LOC112932168Guanine nucleotide-binding protein G(S) subunit alpha isoform X6. (394 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (395 aa)
LOC112932169Neuroendocrine secretory protein 55. (247 aa)
VWFVon Willebrand factor. (2826 aa)
HRASGTPase HRas isoform X1. (189 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
LAMB4Laminin subunit beta-4. (1755 aa)
DLG2-2Disks large homolog 2 isoform X1. (103 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1211 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
COL2A1Collagen alpha-1(II) chain. (1147 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (325 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (591 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (505 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
RBPJLRecombining binding protein suppressor of hairless-like protein. (517 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase. (533 aa)
PARD6GPartitioning defective 6 homolog gamma. (384 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
LOC112913586DLA class I histocompatibility antigen, A9/A9 alpha chain-like isoform X2; Belongs to the MHC class I family. (318 aa)
RBL2Retinoblastoma-like protein 2 isoform X1. (1139 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1. (453 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (96 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LAMB1Laminin subunit beta-1. (1809 aa)
COL4A1Collagen alpha-1(IV) chain. (1580 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
NFX1Transcriptional repressor NF-X1 isoform X1. (1118 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (512 aa)
NOTCH3LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3. (2326 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
OASL2'-5'-oligoadenylate synthase-like protein. (514 aa)
LOC1129328742'-5'-oligoadenylate synthase-like protein 2. (519 aa)
STAT2Signal transducer and activator of transcription. (855 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (618 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1098 aa)
IRF3Interferon regulatory factor 3 isoform X1. (428 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (222 aa)
PARD6BPartitioning defective 6 homolog beta. (364 aa)
SCRIBProtein scribble homolog. (1517 aa)
FASTumor necrosis factor receptor superfamily member 6. (324 aa)
IFNAR1Interferon alpha/beta receptor 1. (569 aa)
BAXApoptosis regulator BAX isoform X2. (192 aa)
IFNAR2Interferon alpha/beta receptor 2 isoform X1. (521 aa)
MFNGbeta-1,3-N-acetylglucosaminyltransferase manic fringe. (315 aa)
TADA3-2Transcriptional adapter 3. (207 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (1450 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1181 aa)
TUBG1-2Tubulin gamma-1 chain. (251 aa)
COL6A2Collagen alpha-2(VI) chain. (960 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ATRSerine/threonine-protein kinase ATR isoform X2; Belongs to the PI3/PI4-kinase family. (2637 aa)
IRF1Interferon regulatory factor. (321 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (548 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (411 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
THBS4Thrombospondin-4. (944 aa)
GPSM3Neurogenic locus notch homolog protein 4 isoform X1. (162 aa)
HES1Transcription factor HES-1. (282 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1143 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X2. (211 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1155 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
COL4A3Collagen alpha-3(IV) chain. (1320 aa)
COL4A4Collagen alpha-4(IV) chain isoform X1. (1688 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
HES2Transcription factor HES-2. (346 aa)
THBS1Thrombospondin-1. (1170 aa)
HES3Transcription factor HES-3. (198 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
PATJinaD-like protein isoform X1. (1144 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
CCNA1cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (401 aa)
FOXO1Forkhead box protein O1. (670 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (727 aa)
RELATranscription factor p65 isoform X2. (542 aa)
HES5Transcription factor HES-5. (139 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
LAMC3Laminin subunit gamma-3. (1475 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (604 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X4. (732 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (878 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
RB1Retinoblastoma-associated protein. (928 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2553 aa)
TSC1Hamartin isoform X1. (1168 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (543 aa)
LAMB2Laminin subunit beta-2 isoform X2. (1850 aa)
UBR4E3 ubiquitin-protein ligase UBR4 isoform X4. (5254 aa)
RBL1Retinoblastoma-like protein 1 isoform X1. (1068 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (498 aa)
IKBKGNF-kappa-B essential modulator isoform X1. (419 aa)
ATP6AP1V-type proton ATPase subunit S1. (464 aa)
TBPL2TATA box-binding protein-like protein 2. (257 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
BCAP31B-cell receptor-associated protein 31. (446 aa)
BADBcl2-associated agonist of cell death. (157 aa)
SOS2Son of sevenless homolog 2. (1308 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
LLGL1Lethal(2) giant larvae protein homolog 1. (1188 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
KRASGTPase KRas isoform X1. (418 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (2471 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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