STRINGSTRING
ENSUAMP00000013817 ENSUAMP00000013817 DMP1 DMP1 ENSUAMP00000000200 ENSUAMP00000000200 GDF6 GDF6 TAFA4 TAFA4 ENSUAMP00000003748 ENSUAMP00000003748 TNFSF11 TNFSF11 PTCH1 PTCH1 ENSUAMP00000009624 ENSUAMP00000009624 ENSUAMP00000010093 ENSUAMP00000010093 ENAM ENAM AMBN AMBN TGFB1 TGFB1 ENSUAMP00000013810 ENSUAMP00000013810 EDAR EDAR EDARADD EDARADD MMP20 MMP20 BMP2 BMP2 TMTC3 TMTC3 ENSUAMP00000024580 ENSUAMP00000024580 ADGRF4 ADGRF4 ADGRF2 ADGRF2 ITGA2 ITGA2 MMP2 MMP2 ENG ENG KLK4 KLK4 AMTN AMTN TUFT1 TUFT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000013817RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (153 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (485 aa)
ENSUAMP00000000200Uncharacterized protein. (157 aa)
GDF6Growth differentiation factor 6. (289 aa)
TAFA4TAFA chemokine like family member 4. (130 aa)
ENSUAMP00000003748Uncharacterized protein. (82 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (242 aa)
PTCH1Patched 1. (1453 aa)
ENSUAMP00000009624Uncharacterized protein. (200 aa)
ENSUAMP00000010093SUFU_C domain-containing protein. (81 aa)
ENAMEnamelin. (1130 aa)
AMBNAmeloblastin. (404 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENSUAMP00000013810RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (164 aa)
EDAREctodysplasin A receptor. (475 aa)
EDARADDEDAR associated death domain. (193 aa)
MMP20Matrix metallopeptidase 20. (483 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (923 aa)
ENSUAMP00000024580Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (241 aa)
ADGRF4Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (695 aa)
ADGRF2Adhesion G protein-coupled receptor F2; Belongs to the G-protein coupled receptor 2 family. (722 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1121 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
ENGEndoglin. (650 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (209 aa)
AMTNAmelotin. (210 aa)
TUFT1Tuftelin 1. (366 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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