STRINGSTRING
PARP6 PARP6 ENSUAMP00000001114 ENSUAMP00000001114 ENSUAMP00000001168 ENSUAMP00000001168 HSPA9 HSPA9 ENSUAMP00000002525 ENSUAMP00000002525 ENSUAMP00000002526 ENSUAMP00000002526 DYRK4 DYRK4 ENSUAMP00000003524 ENSUAMP00000003524 SRL SRL ENSUAMP00000006524 ENSUAMP00000006524 CSRP3 CSRP3 ALB ALB ACAT1 ACAT1 IDH2 IDH2 ENSUAMP00000010491 ENSUAMP00000010491 ACAA2 ACAA2 HADHB HADHB HADHA HADHA ENSUAMP00000010858 ENSUAMP00000010858 ENSUAMP00000010867 ENSUAMP00000010867 GOT2 GOT2 PFKM PFKM MDH2 MDH2 ENSUAMP00000014933 ENSUAMP00000014933 NNT NNT SLC25A4 SLC25A4 ENSUAMP00000016311 ENSUAMP00000016311 OGDH OGDH MYBPC3 MYBPC3 SLC25A5 SLC25A5 VCL VCL ENSUAMP00000020368 ENSUAMP00000020368 OGDHL OGDHL MB MB TNNI3 TNNI3 ENSUAMP00000023108 ENSUAMP00000023108 TF TF ATP5F1A ATP5F1A IDH3A IDH3A SPTAN1 SPTAN1 CKM CKM ENSUAMP00000026219 ENSUAMP00000026219 PGK1 PGK1 ATP5F1B ATP5F1B HSPA8 HSPA8 FLNC FLNC CYCS CYCS GAPDH GAPDH ACO2 ACO2 ANXA6 ANXA6 PGK2 PGK2 MYL2 MYL2 ENSUAMP00000031500 ENSUAMP00000031500 ENSUAMP00000031501 ENSUAMP00000031501 PDHA1 PDHA1 ENSUAMP00000031906 ENSUAMP00000031906 ENSUAMP00000033767 ENSUAMP00000033767 PKM PKM CS CS TPI1 TPI1 HADH HADH PYGB PYGB CKMT2 CKMT2 ENSUAMP00000037342 ENSUAMP00000037342 PDHA2 PDHA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARP6Poly [ADP-ribose] polymerase. (610 aa)
ENSUAMP00000001114GLOBIN domain-containing protein; Belongs to the globin family. (147 aa)
ENSUAMP00000001168GLOBIN domain-containing protein; Belongs to the globin family. (185 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (678 aa)
ENSUAMP00000002525GLOBIN domain-containing protein; Belongs to the globin family. (142 aa)
ENSUAMP00000002526GLOBIN domain-containing protein; Belongs to the globin family. (153 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (519 aa)
ENSUAMP00000003524PFK domain-containing protein. (53 aa)
SRLSarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (807 aa)
ENSUAMP00000006524Peptidase_M16_C domain-containing protein. (384 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
ALBAlbumin. (609 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (421 aa)
ENSUAMP00000010491Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (153 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (812 aa)
ENSUAMP00000010858Myosin_tail_1 domain-containing protein. (890 aa)
ENSUAMP00000010867Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (207 aa)
GOT2Aspartate aminotransferase. (393 aa)
PFKMUncharacterized protein. (862 aa)
MDH2Malate dehydrogenase. (338 aa)
ENSUAMP00000014933Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (286 aa)
NNTNicotinamide nucleotide transhydrogenase. (740 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (361 aa)
ENSUAMP00000016311Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (98 aa)
OGDHOxoglutarate dehydrogenase. (1083 aa)
MYBPC3Myosin binding protein C, cardiac. (1245 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
VCLVinculin. (1066 aa)
ENSUAMP00000020368Peptidase_M16 domain-containing protein. (119 aa)
OGDHLOxoglutarate dehydrogenase like. (1025 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (148 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
ENSUAMP00000023108Uncharacterized protein; Belongs to the transferrin family. (600 aa)
TFTransferrin; Belongs to the transferrin family. (709 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (578 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (380 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2483 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
ENSUAMP00000026219Uncharacterized protein. (132 aa)
PGK1Phosphoglycerate kinase. (417 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
HSPA8Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
FLNCFilamin C. (2681 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (347 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (799 aa)
ANXA6Annexin. (673 aa)
PGK2Phosphoglycerate kinase. (297 aa)
MYL2Myosin light chain 2. (192 aa)
ENSUAMP00000031500Uncharacterized protein. (89 aa)
ENSUAMP00000031501Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
ENSUAMP00000031906Uncharacterized protein. (55 aa)
ENSUAMP00000033767Uncharacterized protein. (60 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
TPI1Triosephosphate isomerase. (249 aa)
HADHHydroxyacyl-CoA dehydrogenase. (374 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
ENSUAMP00000037342Uncharacterized protein. (213 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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