STRINGSTRING
MIB2 MIB2 ENSUAMP00000000292 ENSUAMP00000000292 PSMB2 PSMB2 PSMC4 PSMC4 PSMD1 PSMD1 UBQLN3 UBQLN3 UBQLNL UBQLNL PSMD2 PSMD2 PSMD11 PSMD11 ENSUAMP00000003372 ENSUAMP00000003372 PSMB1 PSMB1 ENSUAMP00000004531 ENSUAMP00000004531 TRAF7 TRAF7 USP14 USP14 ENSUAMP00000005735 ENSUAMP00000005735 PLEKHM2 PLEKHM2 PSMC3 PSMC3 PSMB6 PSMB6 PSMB3 PSMB3 PSMB11 PSMB11 PSMF1 PSMF1 ENSUAMP00000008157 ENSUAMP00000008157 PSMC5 PSMC5 PSMA3 PSMA3 PSMD7 PSMD7 PSME4 PSME4 PSMB5 PSMB5 KATNAL2 KATNAL2 PSMD9 PSMD9 UBQLN2 UBQLN2 UBLCP1 UBLCP1 ENSUAMP00000012220 ENSUAMP00000012220 RAD23A RAD23A NGLY1 NGLY1 PSME3 PSME3 UCHL5 UCHL5 PSMD13 PSMD13 PSMB8 PSMB8 PSMB9 PSMB9 PSMD8 PSMD8 PSMD3 PSMD3 UBQLN4 UBQLN4 PSMD10 PSMD10 CETN2 CETN2 PSMD5 PSMD5 RAD23B RAD23B UBFD1 UBFD1 XPC XPC ENSUAMP00000022022 ENSUAMP00000022022 PAAF1 PAAF1 PSMA4 PSMA4 MPND MPND PSMB4 PSMB4 PSMC2 PSMC2 PSMA1 PSMA1 ENSUAMP00000026056 ENSUAMP00000026056 PSMB10 PSMB10 ECPAS ECPAS ENSUAMP00000029270 ENSUAMP00000029270 DESI1 DESI1 FBXO7 FBXO7 PSMC6 PSMC6 PSMA6 PSMA6 PSME1 PSME1 PSME2 PSME2 UBL4B UBL4B KIAA2012 KIAA2012 PSMA7 PSMA7 PSMB7 PSMB7 PSMA2 PSMA2 ENSUAMP00000034956 ENSUAMP00000034956 UBQLN1 UBQLN1 ENSUAMP00000035945 ENSUAMP00000035945 PSMD4 PSMD4 ENSUAMP00000036637 ENSUAMP00000036637 PSMD12 PSMD12 ENSUAMP00000037175 ENSUAMP00000037175
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MIB2Mindbomb E3 ubiquitin protein ligase 2. (991 aa)
ENSUAMP00000000292PCI domain-containing protein. (389 aa)
PSMB2Proteasome subunit beta. (167 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (400 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (683 aa)
UBQLN3Ubiquilin 3. (650 aa)
UBQLNLUbiquilin like. (580 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (418 aa)
ENSUAMP00000003372Uncharacterized protein. (157 aa)
PSMB1Proteasome subunit beta. (241 aa)
ENSUAMP00000004531AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
TRAF7TNF receptor associated factor 7. (670 aa)
USP14Ubiquitin specific peptidase 14; Belongs to the peptidase C19 family. (350 aa)
ENSUAMP00000005735PROTEASOME_ALPHA_1 domain-containing protein. (80 aa)
PLEKHM2Pleckstrin homology and RUN domain containing M2. (1026 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
PSMB6Proteasome subunit beta. (219 aa)
PSMB3Proteasome subunit beta. (202 aa)
PSMB11Proteasome subunit beta. (292 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSUAMP00000008157Oxysterol-binding protein; Belongs to the OSBP family. (761 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
PSME4Proteasome activator subunit 4. (1436 aa)
PSMB5Proteasome subunit beta. (263 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (529 aa)
PSMD9PDZ domain-containing protein. (309 aa)
UBQLN2Ubiquilin 2. (623 aa)
UBLCP1Ubiquitin like domain containing CTD phosphatase 1. (310 aa)
ENSUAMP00000012220ATPase_AAA_core domain-containing protein. (174 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (362 aa)
NGLY1N-glycanase 1. (654 aa)
PSME3Proteasome activator subunit 3. (254 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (328 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMB9Proteasome subunit beta. (220 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (536 aa)
UBQLN4Ubiquilin 4. (604 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (151 aa)
CETN2Centrin 2. (219 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (408 aa)
UBFD1Ubiquitin family domain containing 1. (347 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (945 aa)
ENSUAMP00000022022Uncharacterized protein. (107 aa)
PAAF1Proteasomal ATPase associated factor 1. (392 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
MPNDMPN domain containing. (509 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
ENSUAMP00000026056MitMem_reg domain-containing protein. (95 aa)
PSMB10Proteasome subunit beta 10. (327 aa)
ECPASEcm29 proteasome adaptor and scaffold. (1975 aa)
ENSUAMP00000029270Uncharacterized protein. (78 aa)
DESI1Desumoylating isopeptidase 1. (169 aa)
FBXO7F-box protein 7. (523 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSME2Proteasome activator subunit 2. (239 aa)
UBL4BUbiquitin like 4B. (154 aa)
KIAA2012KIAA2012. (1131 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ENSUAMP00000034956Uncharacterized protein. (138 aa)
UBQLN1Ubiquilin 1. (589 aa)
ENSUAMP00000035945Ubiquitin-like domain-containing protein. (90 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (344 aa)
ENSUAMP00000036637PCI domain-containing protein. (405 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSUAMP00000037175MPN domain-containing protein. (156 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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