(5 nodes) FasL/ CD95L signaling, and TRAIL signaling network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000007992	Uncharacterized protein. (219 aa)
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (481 aa)
	ENSUAMP00000018082	Uncharacterized protein. (249 aa)
	ENSUAMP00000022738	Uncharacterized protein. (126 aa)
	TNFSF10	Tumor necrosis factor ligand superfamily member. (289 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP10	ENSUAMP00000007992	ENSUAMP00000007994	ENSUAMP00000007992	Caspase 10; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.986
CASP10	ENSUAMP00000018082	ENSUAMP00000007994	ENSUAMP00000018082	Caspase 10; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.895
CASP10	ENSUAMP00000022738	ENSUAMP00000007994	ENSUAMP00000022738	Caspase 10; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.819
CASP10	TNFSF10	ENSUAMP00000007994	ENSUAMP00000023690	Caspase 10; Belongs to the peptidase C14A family.	Tumor necrosis factor ligand superfamily member.	0.790
ENSUAMP00000007992	CASP10	ENSUAMP00000007992	ENSUAMP00000007994	Uncharacterized protein.	Caspase 10; Belongs to the peptidase C14A family.	0.986
ENSUAMP00000007992	ENSUAMP00000018082	ENSUAMP00000007992	ENSUAMP00000018082	Uncharacterized protein.	Uncharacterized protein.	0.808
ENSUAMP00000007992	ENSUAMP00000022738	ENSUAMP00000007992	ENSUAMP00000022738	Uncharacterized protein.	Uncharacterized protein.	0.562
ENSUAMP00000007992	TNFSF10	ENSUAMP00000007992	ENSUAMP00000023690	Uncharacterized protein.	Tumor necrosis factor ligand superfamily member.	0.805
ENSUAMP00000018082	CASP10	ENSUAMP00000018082	ENSUAMP00000007994	Uncharacterized protein.	Caspase 10; Belongs to the peptidase C14A family.	0.895
ENSUAMP00000018082	ENSUAMP00000007992	ENSUAMP00000018082	ENSUAMP00000007992	Uncharacterized protein.	Uncharacterized protein.	0.808
ENSUAMP00000018082	ENSUAMP00000022738	ENSUAMP00000018082	ENSUAMP00000022738	Uncharacterized protein.	Uncharacterized protein.	0.994
ENSUAMP00000018082	TNFSF10	ENSUAMP00000018082	ENSUAMP00000023690	Uncharacterized protein.	Tumor necrosis factor ligand superfamily member.	0.667
ENSUAMP00000022738	CASP10	ENSUAMP00000022738	ENSUAMP00000007994	Uncharacterized protein.	Caspase 10; Belongs to the peptidase C14A family.	0.819
ENSUAMP00000022738	ENSUAMP00000007992	ENSUAMP00000022738	ENSUAMP00000007992	Uncharacterized protein.	Uncharacterized protein.	0.562
ENSUAMP00000022738	ENSUAMP00000018082	ENSUAMP00000022738	ENSUAMP00000018082	Uncharacterized protein.	Uncharacterized protein.	0.994
ENSUAMP00000022738	TNFSF10	ENSUAMP00000022738	ENSUAMP00000023690	Uncharacterized protein.	Tumor necrosis factor ligand superfamily member.	0.643
TNFSF10	CASP10	ENSUAMP00000023690	ENSUAMP00000007994	Tumor necrosis factor ligand superfamily member.	Caspase 10; Belongs to the peptidase C14A family.	0.790
TNFSF10	ENSUAMP00000007992	ENSUAMP00000023690	ENSUAMP00000007992	Tumor necrosis factor ligand superfamily member.	Uncharacterized protein.	0.805
TNFSF10	ENSUAMP00000018082	ENSUAMP00000023690	ENSUAMP00000018082	Tumor necrosis factor ligand superfamily member.	Uncharacterized protein.	0.667
TNFSF10	ENSUAMP00000022738	ENSUAMP00000023690	ENSUAMP00000022738	Tumor necrosis factor ligand superfamily member.	Uncharacterized protein.	0.643