(5 nodes) R-spondin, Fu-CRD domain, and Epithelial cell proliferation involved in renal tubule morphogenesis network (Ursus americanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	ENSUAMP00000005842	RING-type domain-containing protein. (787 aa)
	LGR4	Leucine rich repeat containing G protein-coupled receptor 4. (971 aa)
	RSPO1	R-spondin 1. (263 aa)
	RSPO3	R-spondin 3. (275 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUAMP00000005842	LGR4	ENSUAMP00000005842	ENSUAMP00000015398	RING-type domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 4.	0.939
ENSUAMP00000005842	LGR5	ENSUAMP00000005842	ENSUAMP00000002203	RING-type domain-containing protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.974
ENSUAMP00000005842	RSPO1	ENSUAMP00000005842	ENSUAMP00000017799	RING-type domain-containing protein.	R-spondin 1.	0.996
ENSUAMP00000005842	RSPO3	ENSUAMP00000005842	ENSUAMP00000035356	RING-type domain-containing protein.	R-spondin 3.	0.981
LGR4	ENSUAMP00000005842	ENSUAMP00000015398	ENSUAMP00000005842	Leucine rich repeat containing G protein-coupled receptor 4.	RING-type domain-containing protein.	0.939
LGR4	LGR5	ENSUAMP00000015398	ENSUAMP00000002203	Leucine rich repeat containing G protein-coupled receptor 4.	Leucine rich repeat containing G protein-coupled receptor 5.	0.952
LGR4	RSPO1	ENSUAMP00000015398	ENSUAMP00000017799	Leucine rich repeat containing G protein-coupled receptor 4.	R-spondin 1.	0.998
LGR4	RSPO3	ENSUAMP00000015398	ENSUAMP00000035356	Leucine rich repeat containing G protein-coupled receptor 4.	R-spondin 3.	0.988
LGR5	ENSUAMP00000005842	ENSUAMP00000002203	ENSUAMP00000005842	Leucine rich repeat containing G protein-coupled receptor 5.	RING-type domain-containing protein.	0.974
LGR5	LGR4	ENSUAMP00000002203	ENSUAMP00000015398	Leucine rich repeat containing G protein-coupled receptor 5.	Leucine rich repeat containing G protein-coupled receptor 4.	0.952
LGR5	RSPO1	ENSUAMP00000002203	ENSUAMP00000017799	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 1.	0.998
LGR5	RSPO3	ENSUAMP00000002203	ENSUAMP00000035356	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 3.	0.983
RSPO1	ENSUAMP00000005842	ENSUAMP00000017799	ENSUAMP00000005842	R-spondin 1.	RING-type domain-containing protein.	0.996
RSPO1	LGR4	ENSUAMP00000017799	ENSUAMP00000015398	R-spondin 1.	Leucine rich repeat containing G protein-coupled receptor 4.	0.998
RSPO1	LGR5	ENSUAMP00000017799	ENSUAMP00000002203	R-spondin 1.	Leucine rich repeat containing G protein-coupled receptor 5.	0.998
RSPO1	RSPO3	ENSUAMP00000017799	ENSUAMP00000035356	R-spondin 1.	R-spondin 3.	0.896
RSPO3	ENSUAMP00000005842	ENSUAMP00000035356	ENSUAMP00000005842	R-spondin 3.	RING-type domain-containing protein.	0.981
RSPO3	LGR4	ENSUAMP00000035356	ENSUAMP00000015398	R-spondin 3.	Leucine rich repeat containing G protein-coupled receptor 4.	0.988
RSPO3	LGR5	ENSUAMP00000035356	ENSUAMP00000002203	R-spondin 3.	Leucine rich repeat containing G protein-coupled receptor 5.	0.983
RSPO3	RSPO1	ENSUAMP00000035356	ENSUAMP00000017799	R-spondin 3.	R-spondin 1.	0.896