(42 nodes) Magnesium-dependent protein serine/threonine phosphatase complex, and E2F mediated regulation of DNA replication network (Ursus americanus)

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second shell of interactors

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Predicted Interactions

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Your Input:
	PPP2R2C	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (425 aa)
	ENSUAMP00000001591	Uncharacterized protein. (65 aa)
	PPP4R1	Protein phosphatase 4 regulatory subunit 1. (937 aa)
	ENSUAMP00000006374	Uncharacterized protein. (178 aa)
	ENSUAMP00000010957	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (61 aa)
	PPP2R2D	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (449 aa)
	PPP4R3C	Protein phosphatase 4 regulatory subunit 3C. (694 aa)
	PPP1R1A	Protein phosphatase 1 regulatory inhibitor subunit 1A. (171 aa)
	SPRTN	SprT-like N-terminal domain. (509 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	ENSUAMP00000014981	EF-hand domain-containing protein. (176 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
	ENSUAMP00000015653	Uncharacterized protein. (172 aa)
	ENSUAMP00000015656	Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
	PPP4R2	Protein phosphatase 4 regulatory subunit 2. (415 aa)
	PPP2R3A	Protein phosphatase 2 regulatory subunit B''alpha. (1153 aa)
	ENSUAMP00000019729	Uncharacterized protein. (341 aa)
	PPP4R4	Protein phosphatase 4 regulatory subunit 4. (751 aa)
	ENSUAMP00000020385	Uncharacterized protein. (132 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (498 aa)
	PPP2R2B	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (601 aa)
	ENSUAMP00000022173	Uncharacterized protein. (86 aa)
	LCMT1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (333 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (504 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	PPP4R3B	Protein phosphatase 4 regulatory subunit 3B. (817 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (503 aa)
	RELCH	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (777 aa)
	ZCCHC2	Zinc finger CCHC-type containing 2. (1145 aa)
	PPP2R2A	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (458 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	CCDC142	Coiled-coil domain containing 142. (747 aa)
	PPP2R3C	Protein phosphatase 2 regulatory subunit B''gamma. (450 aa)
	ENSUAMP00000030716	Uncharacterized protein. (98 aa)
	RFLNA	Refilin A. (214 aa)
	PPP4R3A	Protein phosphatase 4 regulatory subunit 3A. (820 aa)
	PPP4C	Serine/threonine-protein phosphatase. (311 aa)
	FBXO28	F-box protein 28. (368 aa)
	ENSUAMP00000032533	Uncharacterized protein. (127 aa)
	ENSUAMP00000032535	Uncharacterized protein. (145 aa)
	TIPRL	TOR signaling pathway regulator. (240 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC142	PPP2CA	ENSUAMP00000028082	ENSUAMP00000023173	Coiled-coil domain containing 142.	Serine/threonine-protein phosphatase.	0.405
CCDC142	PPP2CB	ENSUAMP00000028082	ENSUAMP00000027584	Coiled-coil domain containing 142.	Serine/threonine-protein phosphatase.	0.405
CCDC142	PPP2R2A	ENSUAMP00000028082	ENSUAMP00000026618	Coiled-coil domain containing 142.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.445
CCDC142	PPP2R2B	ENSUAMP00000028082	ENSUAMP00000021452	Coiled-coil domain containing 142.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.445
CCDC142	PPP2R3C	ENSUAMP00000028082	ENSUAMP00000030579	Coiled-coil domain containing 142.	Protein phosphatase 2 regulatory subunit B''gamma.	0.452
ENSUAMP00000001591	ENSUAMP00000030716	ENSUAMP00000001591	ENSUAMP00000030716	Uncharacterized protein.	Uncharacterized protein.	0.873
ENSUAMP00000001591	ENSUAMP00000032533	ENSUAMP00000001591	ENSUAMP00000032533	Uncharacterized protein.	Uncharacterized protein.	0.939
ENSUAMP00000001591	ENSUAMP00000032535	ENSUAMP00000001591	ENSUAMP00000032535	Uncharacterized protein.	Uncharacterized protein.	0.912
ENSUAMP00000001591	PPP2CA	ENSUAMP00000001591	ENSUAMP00000023173	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.958
ENSUAMP00000001591	PPP2CB	ENSUAMP00000001591	ENSUAMP00000027584	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.945
ENSUAMP00000001591	PPP2R1A	ENSUAMP00000001591	ENSUAMP00000013119	Uncharacterized protein.	Protein phosphatase 2 scaffold subunit Aalpha.	0.940
ENSUAMP00000001591	PPP2R5A	ENSUAMP00000001591	ENSUAMP00000020392	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.905
ENSUAMP00000001591	PPP2R5B	ENSUAMP00000001591	ENSUAMP00000015263	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.905
ENSUAMP00000001591	PPP2R5C	ENSUAMP00000001591	ENSUAMP00000024032	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.940
ENSUAMP00000001591	PPP2R5D	ENSUAMP00000001591	ENSUAMP00000022135	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.942
ENSUAMP00000001591	PPP2R5E	ENSUAMP00000001591	ENSUAMP00000022315	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.873
ENSUAMP00000006374	ENSUAMP00000010957	ENSUAMP00000006374	ENSUAMP00000010957	Uncharacterized protein.	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.	0.617
ENSUAMP00000006374	ENSUAMP00000014981	ENSUAMP00000006374	ENSUAMP00000014981	Uncharacterized protein.	EF-hand domain-containing protein.	0.488
ENSUAMP00000006374	ENSUAMP00000020385	ENSUAMP00000006374	ENSUAMP00000020385	Uncharacterized protein.	Uncharacterized protein.	0.412
ENSUAMP00000006374	ENSUAMP00000030716	ENSUAMP00000006374	ENSUAMP00000030716	Uncharacterized protein.	Uncharacterized protein.	0.535