48 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGF14	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
	ENSUAMP00000000316	Homeobox domain-containing protein. (280 aa)
	ENSUAMP00000000600	Uncharacterized protein. (130 aa)
	sry	Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development; Belongs to the SRY family. (221 aa)
	ENSUAMP00000001583	annotation not available (221 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1017 aa)
	ENSUAMP00000003809	Thyroglobulin type-1 domain-containing protein. (168 aa)
	TFCP2L1	Transcription factor CP2 like 1. (479 aa)
	ENSUAMP00000008401	TGF_BETA_2 domain-containing protein. (367 aa)
	ENSUAMP00000008430	Uncharacterized protein. (665 aa)
	SOX4	Transcription factor SOX. (452 aa)
	KRT19	Keratin 19; Belongs to the intermediate filament family. (407 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	ENSUAMP00000010229	Uncharacterized protein. (191 aa)
	SALL4	Spalt like transcription factor 4. (1053 aa)
	TWIST2	Twist family bHLH transcription factor 2. (160 aa)
	ENSUAMP00000014216	Homeobox domain-containing protein. (315 aa)
	GDF3	Growth differentiation factor 3. (365 aa)
	ENSUAMP00000015591	Uncharacterized protein. (184 aa)
	ENSUAMP00000016349	Uncharacterized protein. (121 aa)
	TMEFF1	Transmembrane protein with EGF like and two follistatin like domains 1. (380 aa)
	MSANTD3	Myb/SANT DNA binding domain containing 3. (274 aa)
	TDGF1	Teratocarcinoma-derived growth factor 1. (184 aa)
	ENSUAMP00000017830	Uncharacterized protein. (157 aa)
	SNAI2	Snail family transcriptional repressor 2. (230 aa)
	ENSUAMP00000019295	Uncharacterized protein. (386 aa)
	ENSUAMP00000020330	IF rod domain-containing protein. (128 aa)
	KLF4	Kruppel like factor 4. (487 aa)
	ENSUAMP00000021933	Uncharacterized protein. (105 aa)
	SOX2	SRY-box transcription factor 2. (321 aa)
	ESRRB	Estrogen related receptor beta. (454 aa)
	KRT18	Keratin 18; Belongs to the intermediate filament family. (443 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (471 aa)
	ENSUAMP00000031917	Uncharacterized protein. (79 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	ENSUAMP00000034063	Uncharacterized protein. (452 aa)
	PXDN	Peroxidasin. (905 aa)
	ANXA5	Annexin. (294 aa)
	CBFA2T2	CBFA2/RUNX1 partner transcriptional co-repressor 2. (575 aa)
	SNAI1	Snail family transcriptional repressor 1. (259 aa)
	ENSUAMP00000035029	POU domain protein. (360 aa)
	PRDM14	PR/SET domain 14. (566 aa)
	FBXO15	F-box protein 15. (436 aa)
	ZEB2	Zinc finger E-box binding homeobox 2. (1214 aa)
	SOX17	SRY-box transcription factor 17. (406 aa)
	EOMES	Eomesodermin. (687 aa)
	ENSUAMP00000037554	Ig-like domain-containing protein. (361 aa)
	ENSUAMP00000037566	TGF_BETA_2 domain-containing protein. (293 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA5	ENSUAMP00000003809	ENSUAMP00000034552	ENSUAMP00000003809	Annexin.	Thyroglobulin type-1 domain-containing protein.	0.465
ANXA5	ENSUAMP00000008430	ENSUAMP00000034552	ENSUAMP00000008430	Annexin.	Uncharacterized protein.	0.558
ANXA5	ENSUAMP00000014216	ENSUAMP00000034552	ENSUAMP00000014216	Annexin.	Homeobox domain-containing protein.	0.482
ANXA5	ENSUAMP00000031917	ENSUAMP00000034552	ENSUAMP00000031917	Annexin.	Uncharacterized protein.	0.453
ANXA5	ENSUAMP00000037554	ENSUAMP00000034552	ENSUAMP00000037554	Annexin.	Ig-like domain-containing protein.	0.558
ANXA5	PXDN	ENSUAMP00000034552	ENSUAMP00000034490	Annexin.	Peroxidasin.	0.558
ANXA5	SNAI2	ENSUAMP00000034552	ENSUAMP00000018871	Annexin.	Snail family transcriptional repressor 2.	0.465
ANXA5	ZEB1	ENSUAMP00000034552	ENSUAMP00000002169	Annexin.	Zinc finger E-box binding homeobox 1.	0.459
CBFA2T2	PRDM14	ENSUAMP00000034614	ENSUAMP00000035284	CBFA2/RUNX1 partner transcriptional co-repressor 2.	PR/SET domain 14.	0.827
ENSUAMP00000000316	ENSUAMP00000001583	ENSUAMP00000000316	ENSUAMP00000001583	Homeobox domain-containing protein.	annotation not available	0.401
ENSUAMP00000000316	ENSUAMP00000014216	ENSUAMP00000000316	ENSUAMP00000014216	Homeobox domain-containing protein.	Homeobox domain-containing protein.	0.703
ENSUAMP00000000316	ENSUAMP00000015591	ENSUAMP00000000316	ENSUAMP00000015591	Homeobox domain-containing protein.	Uncharacterized protein.	0.471
ENSUAMP00000000316	ENSUAMP00000016349	ENSUAMP00000000316	ENSUAMP00000016349	Homeobox domain-containing protein.	Uncharacterized protein.	0.471
ENSUAMP00000000316	ENSUAMP00000035029	ENSUAMP00000000316	ENSUAMP00000035029	Homeobox domain-containing protein.	POU domain protein.	0.471
ENSUAMP00000000316	EOMES	ENSUAMP00000000316	ENSUAMP00000036778	Homeobox domain-containing protein.	Eomesodermin.	0.617
ENSUAMP00000000316	SOX17	ENSUAMP00000000316	ENSUAMP00000036659	Homeobox domain-containing protein.	SRY-box transcription factor 17.	0.713
ENSUAMP00000000316	SOX2	ENSUAMP00000000316	ENSUAMP00000023439	Homeobox domain-containing protein.	SRY-box transcription factor 2.	0.401
ENSUAMP00000000316	sry	ENSUAMP00000000316	ENSUAMP00000001553	Homeobox domain-containing protein.	Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development; Belongs to the SRY family.	0.401
ENSUAMP00000000600	ENSUAMP00000014216	ENSUAMP00000000600	ENSUAMP00000014216	Uncharacterized protein.	Homeobox domain-containing protein.	0.702
ENSUAMP00000000600	ENSUAMP00000015591	ENSUAMP00000000600	ENSUAMP00000015591	Uncharacterized protein.	Uncharacterized protein.	0.491