6 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGR	Progesterone receptor. (634 aa)
	ESR1	Estrogen receptor 1. (490 aa)
	CARM1	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (636 aa)
	NCOA1	Nuclear receptor coactivator. (1441 aa)
	SP1	Sp1 transcription factor. (780 aa)
	NCOA3	Nuclear receptor coactivator. (1431 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARM1	ESR1	ENSUAMP00000007500	ENSUAMP00000006270	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Estrogen receptor 1.	0.969
CARM1	NCOA1	ENSUAMP00000007500	ENSUAMP00000008682	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.770
CARM1	NCOA3	ENSUAMP00000007500	ENSUAMP00000025028	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.984
CARM1	SP1	ENSUAMP00000007500	ENSUAMP00000013622	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Sp1 transcription factor.	0.929
ESR1	CARM1	ENSUAMP00000006270	ENSUAMP00000007500	Estrogen receptor 1.	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.969
ESR1	NCOA1	ENSUAMP00000006270	ENSUAMP00000008682	Estrogen receptor 1.	Nuclear receptor coactivator.	0.997
ESR1	NCOA3	ENSUAMP00000006270	ENSUAMP00000025028	Estrogen receptor 1.	Nuclear receptor coactivator.	0.996
ESR1	PGR	ENSUAMP00000006270	ENSUAMP00000000820	Estrogen receptor 1.	Progesterone receptor.	0.971
ESR1	SP1	ENSUAMP00000006270	ENSUAMP00000013622	Estrogen receptor 1.	Sp1 transcription factor.	0.993
NCOA1	CARM1	ENSUAMP00000008682	ENSUAMP00000007500	Nuclear receptor coactivator.	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.770
NCOA1	ESR1	ENSUAMP00000008682	ENSUAMP00000006270	Nuclear receptor coactivator.	Estrogen receptor 1.	0.997
NCOA1	NCOA3	ENSUAMP00000008682	ENSUAMP00000025028	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.974
NCOA1	PGR	ENSUAMP00000008682	ENSUAMP00000000820	Nuclear receptor coactivator.	Progesterone receptor.	0.987
NCOA1	SP1	ENSUAMP00000008682	ENSUAMP00000013622	Nuclear receptor coactivator.	Sp1 transcription factor.	0.946
NCOA3	CARM1	ENSUAMP00000025028	ENSUAMP00000007500	Nuclear receptor coactivator.	Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.984
NCOA3	ESR1	ENSUAMP00000025028	ENSUAMP00000006270	Nuclear receptor coactivator.	Estrogen receptor 1.	0.996
NCOA3	NCOA1	ENSUAMP00000025028	ENSUAMP00000008682	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.974
NCOA3	PGR	ENSUAMP00000025028	ENSUAMP00000000820	Nuclear receptor coactivator.	Progesterone receptor.	0.970
NCOA3	SP1	ENSUAMP00000025028	ENSUAMP00000013622	Nuclear receptor coactivator.	Sp1 transcription factor.	0.948
PGR	ESR1	ENSUAMP00000000820	ENSUAMP00000006270	Progesterone receptor.	Estrogen receptor 1.	0.971