(28 nodes) Cysteine-type deubiquitinase activity network (Ursus americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OTUD6B	OTU domain containing 6B. (324 aa)
	RNF41	Ring finger protein 41. (246 aa)
	UCHL3	Ubiquitin carboxyl-terminal hydrolase. (230 aa)
	OTUD3	OTU deubiquitinase 3. (398 aa)
	ENSUAMP00000013636	Uncharacterized protein. (265 aa)
	ENSUAMP00000014067	Uncharacterized protein. (82 aa)
	ZUP1	Zinc finger containing ubiquitin peptidase 1. (579 aa)
	JOSD2	Josephin domain containing 2. (188 aa)
	USP2	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (606 aa)
	OTUB1	Ubiquitin thioesterase. (271 aa)
	ZRANB1	Zinc finger RANBP2-type containing 1. (708 aa)
	USP33	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (917 aa)
	USP40	Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1225 aa)
	USP43	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1032 aa)
	RNF128	Ring finger protein 128. (402 aa)
	USP28	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1145 aa)
	VCPIP1	Valosin containing protein interacting protein 1. (1221 aa)
	ENSUAMP00000025923	Josephin domain-containing protein. (64 aa)
	USPL1	Ubiquitin specific peptidase like 1. (907 aa)
	USP7	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1055 aa)
	USP25	Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1113 aa)
	UVSSA	UV stimulated scaffold protein A. (698 aa)
	OTUD7B	OTU deubiquitinase 7B. (844 aa)
	USP45	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (769 aa)
	USP50	Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (366 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1116 aa)
	USP5	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (891 aa)
	USP11	Ubiquitin specific peptidase 11; Belongs to the peptidase C19 family. (917 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUAMP00000013636	ENSUAMP00000014067	ENSUAMP00000013636	ENSUAMP00000014067	Uncharacterized protein.	Uncharacterized protein.	0.647
ENSUAMP00000013636	ENSUAMP00000025923	ENSUAMP00000013636	ENSUAMP00000025923	Uncharacterized protein.	Josephin domain-containing protein.	0.453
ENSUAMP00000013636	OTUB1	ENSUAMP00000013636	ENSUAMP00000019279	Uncharacterized protein.	Ubiquitin thioesterase.	0.631
ENSUAMP00000013636	OTUD6B	ENSUAMP00000013636	ENSUAMP00000004476	Uncharacterized protein.	OTU domain containing 6B.	0.627
ENSUAMP00000013636	OTUD7B	ENSUAMP00000013636	ENSUAMP00000029141	Uncharacterized protein.	OTU deubiquitinase 7B.	0.647
ENSUAMP00000013636	UCHL3	ENSUAMP00000013636	ENSUAMP00000011894	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.523
ENSUAMP00000013636	USP11	ENSUAMP00000013636	ENSUAMP00000037131	Uncharacterized protein.	Ubiquitin specific peptidase 11; Belongs to the peptidase C19 family.	0.470
ENSUAMP00000013636	USP25	ENSUAMP00000013636	ENSUAMP00000027471	Uncharacterized protein.	Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.	0.452
ENSUAMP00000013636	USP43	ENSUAMP00000013636	ENSUAMP00000021816	Uncharacterized protein.	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family.	0.454
ENSUAMP00000013636	USP50	ENSUAMP00000013636	ENSUAMP00000031814	Uncharacterized protein.	Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family.	0.451
ENSUAMP00000013636	USP8	ENSUAMP00000013636	ENSUAMP00000031815	Uncharacterized protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.463
ENSUAMP00000013636	VCPIP1	ENSUAMP00000013636	ENSUAMP00000024493	Uncharacterized protein.	Valosin containing protein interacting protein 1.	0.727
ENSUAMP00000013636	ZUP1	ENSUAMP00000013636	ENSUAMP00000015845	Uncharacterized protein.	Zinc finger containing ubiquitin peptidase 1.	0.475
ENSUAMP00000014067	ENSUAMP00000013636	ENSUAMP00000014067	ENSUAMP00000013636	Uncharacterized protein.	Uncharacterized protein.	0.647
ENSUAMP00000014067	JOSD2	ENSUAMP00000014067	ENSUAMP00000017659	Uncharacterized protein.	Josephin domain containing 2.	0.413
ENSUAMP00000014067	OTUB1	ENSUAMP00000014067	ENSUAMP00000019279	Uncharacterized protein.	Ubiquitin thioesterase.	0.548
ENSUAMP00000014067	OTUD3	ENSUAMP00000014067	ENSUAMP00000012958	Uncharacterized protein.	OTU deubiquitinase 3.	0.624
ENSUAMP00000014067	OTUD6B	ENSUAMP00000014067	ENSUAMP00000004476	Uncharacterized protein.	OTU domain containing 6B.	0.448
ENSUAMP00000014067	USP28	ENSUAMP00000014067	ENSUAMP00000022990	Uncharacterized protein.	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.	0.463
ENSUAMP00000014067	USP45	ENSUAMP00000014067	ENSUAMP00000031159	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.437