(13 nodes) Glutathione peroxidase activity, and Glutathione disulfide oxidoreductase activity network (Ursus americanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GSTO1	Glutathione S-transferase omega 1; Belongs to the GST superfamily. (278 aa)
	GSTM3	Glutathione S-transferase. (226 aa)
	GPX2	Glutathione peroxidase 2. (175 aa)
	ENSUAMP00000005458	Uncharacterized protein. (51 aa)
	ENSUAMP00000009044	Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
	GPX1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	ENSUAMP00000013435	Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
	MGST3	Microsomal glutathione S-transferase 3. (152 aa)
	GSR	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (519 aa)
	ENSUAMP00000029152	Thioredoxin domain-containing protein. (268 aa)
	GPX3	Glutathione peroxidase 3. (218 aa)
	TXNDC12	Thioredoxin domain containing 12. (172 aa)
	GPX8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUAMP00000005458	ENSUAMP00000009044	ENSUAMP00000005458	ENSUAMP00000009044	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.920
ENSUAMP00000005458	ENSUAMP00000013435	ENSUAMP00000005458	ENSUAMP00000013435	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.920
ENSUAMP00000005458	ENSUAMP00000029152	ENSUAMP00000005458	ENSUAMP00000029152	Uncharacterized protein.	Thioredoxin domain-containing protein.	0.954
ENSUAMP00000005458	GPX1	ENSUAMP00000005458	ENSUAMP00000012407	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.923
ENSUAMP00000005458	GPX2	ENSUAMP00000005458	ENSUAMP00000004790	Uncharacterized protein.	Glutathione peroxidase 2.	0.918
ENSUAMP00000005458	GPX3	ENSUAMP00000005458	ENSUAMP00000030550	Uncharacterized protein.	Glutathione peroxidase 3.	0.927
ENSUAMP00000005458	GPX8	ENSUAMP00000005458	ENSUAMP00000036416	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.918
ENSUAMP00000005458	GSR	ENSUAMP00000005458	ENSUAMP00000027588	Uncharacterized protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.950
ENSUAMP00000005458	GSTM3	ENSUAMP00000005458	ENSUAMP00000004100	Uncharacterized protein.	Glutathione S-transferase.	0.923
ENSUAMP00000005458	GSTO1	ENSUAMP00000005458	ENSUAMP00000002571	Uncharacterized protein.	Glutathione S-transferase omega 1; Belongs to the GST superfamily.	0.936
ENSUAMP00000005458	MGST3	ENSUAMP00000005458	ENSUAMP00000017161	Uncharacterized protein.	Microsomal glutathione S-transferase 3.	0.957
ENSUAMP00000005458	TXNDC12	ENSUAMP00000005458	ENSUAMP00000034750	Uncharacterized protein.	Thioredoxin domain containing 12.	0.946
ENSUAMP00000009044	ENSUAMP00000005458	ENSUAMP00000009044	ENSUAMP00000005458	Uncharacterized protein; Belongs to the GST superfamily.	Uncharacterized protein.	0.920
ENSUAMP00000009044	ENSUAMP00000013435	ENSUAMP00000009044	ENSUAMP00000013435	Uncharacterized protein; Belongs to the GST superfamily.	Uncharacterized protein; Belongs to the GST superfamily.	0.911
ENSUAMP00000009044	ENSUAMP00000029152	ENSUAMP00000009044	ENSUAMP00000029152	Uncharacterized protein; Belongs to the GST superfamily.	Thioredoxin domain-containing protein.	0.952
ENSUAMP00000009044	GPX1	ENSUAMP00000009044	ENSUAMP00000012407	Uncharacterized protein; Belongs to the GST superfamily.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.923
ENSUAMP00000009044	GPX2	ENSUAMP00000009044	ENSUAMP00000004790	Uncharacterized protein; Belongs to the GST superfamily.	Glutathione peroxidase 2.	0.920
ENSUAMP00000009044	GPX3	ENSUAMP00000009044	ENSUAMP00000030550	Uncharacterized protein; Belongs to the GST superfamily.	Glutathione peroxidase 3.	0.921
ENSUAMP00000009044	GPX8	ENSUAMP00000009044	ENSUAMP00000036416	Uncharacterized protein; Belongs to the GST superfamily.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.923
ENSUAMP00000009044	GSR	ENSUAMP00000009044	ENSUAMP00000027588	Uncharacterized protein; Belongs to the GST superfamily.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.949