STRINGSTRING
ENSUAMP00000002618 ENSUAMP00000002618 ENSUAMP00000003497 ENSUAMP00000003497 H3F3B H3F3B H2AZ1 H2AZ1 MACROH2A2 MACROH2A2 ENSUAMP00000004341 ENSUAMP00000004341 H2BC1 H2BC1 ENSUAMP00000006202 ENSUAMP00000006202 ENSUAMP00000006306 ENSUAMP00000006306 ENSUAMP00000006323 ENSUAMP00000006323 ENSUAMP00000006330 ENSUAMP00000006330 ENSUAMP00000006335 ENSUAMP00000006335 ENSUAMP00000006561 ENSUAMP00000006561 ENSUAMP00000006568 ENSUAMP00000006568 ENSUAMP00000007225 ENSUAMP00000007225 ENSUAMP00000007257 ENSUAMP00000007257 HDAC11 HDAC11 ENSUAMP00000011802 ENSUAMP00000011802 HDAC4 HDAC4 ENSUAMP00000014195 ENSUAMP00000014195 ENSUAMP00000014212 ENSUAMP00000014212 ENSUAMP00000014243 ENSUAMP00000014243 ENSUAMP00000014255 ENSUAMP00000014255 ENSUAMP00000014288 ENSUAMP00000014288 ENSUAMP00000014302 ENSUAMP00000014302 ENSUAMP00000016112 ENSUAMP00000016112 HDAC10 HDAC10 ENSUAMP00000017034 ENSUAMP00000017034 HIST3H2BB HIST3H2BB H2AW H2AW MACROH2A1 MACROH2A1 ENSUAMP00000017147 ENSUAMP00000017147 ENSUAMP00000020339 ENSUAMP00000020339 H2AC6 H2AC6 ENSUAMP00000020808 ENSUAMP00000020808 ENSUAMP00000020825 ENSUAMP00000020825 ENSUAMP00000020853 ENSUAMP00000020853 GLYR1 GLYR1 ENSUAMP00000022269 ENSUAMP00000022269 ENSUAMP00000022270 ENSUAMP00000022270 HDAC9 HDAC9 H3-3A H3-3A ENSUAMP00000029147 ENSUAMP00000029147 H2AC21 H2AC21 ENSUAMP00000029191 ENSUAMP00000029191 ENSUAMP00000029193 ENSUAMP00000029193 ENSUAMP00000029194 ENSUAMP00000029194 ENSUAMP00000029196 ENSUAMP00000029196 H2BC18 H2BC18 H2BE1 H2BE1 ENSUAMP00000029966 ENSUAMP00000029966 KDM1A KDM1A ENSUAMP00000031302 ENSUAMP00000031302 ENSUAMP00000032223 ENSUAMP00000032223 H2BC11 H2BC11 ENSUAMP00000033915 ENSUAMP00000033915 ENSUAMP00000033919 ENSUAMP00000033919 ENSUAMP00000033920 ENSUAMP00000033920 ENSUAMP00000033942 ENSUAMP00000033942 ENSUAMP00000033945 ENSUAMP00000033945 ENSUAMP00000033947 ENSUAMP00000033947 ENSUAMP00000033949 ENSUAMP00000033949 ENSUAMP00000033950 ENSUAMP00000033950 ENSUAMP00000034736 ENSUAMP00000034736 HDAC7 HDAC7 ENSUAMP00000036902 ENSUAMP00000036902 KDM6A KDM6A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSUAMP00000002618Histone H2A; Belongs to the histone H2A family. (113 aa)
ENSUAMP00000003497Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (159 aa)
MACROH2A2H2A histone family member Y2; Belongs to the histone H2A family. (392 aa)
ENSUAMP00000004341annotation not available (103 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ENSUAMP00000006202JmjC domain-containing protein. (934 aa)
ENSUAMP00000006306annotation not available (103 aa)
ENSUAMP00000006323Histone H3; Belongs to the histone H3 family. (136 aa)
ENSUAMP00000006330Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000006335Histone H2B; Belongs to the histone H2B family. (135 aa)
ENSUAMP00000006561Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000006568annotation not available (130 aa)
ENSUAMP00000007225Histone domain-containing protein; Belongs to the histone H2B family. (122 aa)
ENSUAMP00000007257Hist_deacetyl domain-containing protein. (252 aa)
HDAC11Histone deacetylase 11. (347 aa)
ENSUAMP00000011802Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1116 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (815 aa)
ENSUAMP00000014195annotation not available (130 aa)
ENSUAMP00000014212annotation not available (126 aa)
ENSUAMP00000014243Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014255Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000014288Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000014302Histone H2A; Belongs to the histone H2A family. (141 aa)
ENSUAMP00000016112TPR_REGION domain-containing protein. (215 aa)
HDAC10Histone deacetylase 10. (668 aa)
ENSUAMP00000017034Uncharacterized protein. (1244 aa)
HIST3H2BBHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AWHistone H2A; Belongs to the histone H2A family. (130 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
ENSUAMP00000017147Histone H3; Belongs to the histone H3 family. (91 aa)
ENSUAMP00000020339Uncharacterized protein. (86 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000020808annotation not available (126 aa)
ENSUAMP00000020825annotation not available (103 aa)
ENSUAMP00000020853Histone domain-containing protein. (178 aa)
GLYR1Glyoxylate reductase 1 homolog. (553 aa)
ENSUAMP00000022269Histone H2A; Belongs to the histone H2A family. (132 aa)
ENSUAMP00000022270Histone H2B; Belongs to the histone H2B family. (127 aa)
HDAC9Histone deacetylase 9. (587 aa)
H3-3AHistone domain-containing protein. (142 aa)
ENSUAMP00000029147Histone H2A; Belongs to the histone H2A family. (128 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000029191Histone H2B; Belongs to the histone H2B family. (135 aa)
ENSUAMP00000029193annotation not available (126 aa)
ENSUAMP00000029194Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSUAMP00000029196Histone H3; Belongs to the histone H3 family. (136 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (166 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
ENSUAMP00000029966annotation not available (113 aa)
KDM1ALysine demethylase 1A. (734 aa)
ENSUAMP00000031302Histone domain-containing protein; Belongs to the histone H2B family. (170 aa)
ENSUAMP00000032223Uncharacterized protein. (113 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSUAMP00000033915Histone domain-containing protein. (125 aa)
ENSUAMP00000033919Histone domain-containing protein; Belongs to the histone H2B family. (128 aa)
ENSUAMP00000033920annotation not available (128 aa)
ENSUAMP00000033942annotation not available (130 aa)
ENSUAMP00000033945Histone H3; Belongs to the histone H3 family. (93 aa)
ENSUAMP00000033947Histone H2A; Belongs to the histone H2A family. (136 aa)
ENSUAMP00000033949annotation not available (126 aa)
ENSUAMP00000033950annotation not available (103 aa)
ENSUAMP00000034736HDAC4_Gln domain-containing protein. (230 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (963 aa)
ENSUAMP00000036902Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (388 aa)
KDM6ALysine demethylase 6A. (1381 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.