27 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	KDM6A	Lysine demethylase 6A. (1381 aa)
	LHX1	LIM homeobox 1. (406 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	TASOR	Transcription activation suppressor. (1518 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (507 aa)
	TBX6	T-box transcription factor 6. (436 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)
	SMAD6	Mothers against decapentaplegic homolog. (484 aa)
	ENSUAMP00000025530	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (458 aa)
	TDRKH	Tudor and KH domain containing. (581 aa)
	C2CD3	C2 domain containing 3 centriole elongation regulator. (2209 aa)
	TDRD6	Tudor domain containing 6. (2100 aa)
	ENSUAMP00000017830	Uncharacterized protein. (157 aa)
	TIFAB	TIFA inhibitor. (187 aa)
	NEUROG1	Neurogenin 1. (251 aa)
	MTHFSD	Methenyltetrahydrofolate synthetase domain containing. (318 aa)
	CHRDL1	Chordin like 1. (414 aa)
	COBL	Cordon-bleu WH2 repeat protein. (1250 aa)
	ENSUAMP00000011871	PLAC domain-containing protein. (308 aa)
	TDRD1	Tudor domain containing 1. (1155 aa)
	ENSUAMP00000010701	Uncharacterized protein. (51 aa)
	PTCH1	Patched 1. (1453 aa)
	MESP2	Mesoderm posterior bHLH transcription factor 2. (376 aa)
	PLD6	Phospholipase D family member 6. (229 aa)
	TDRD15	Tudor domain containing 15. (1940 aa)
	ENSUAMP00000000600	Uncharacterized protein. (130 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSUAMP00000011871	ENSUAMP00000025530	ENSUAMP00000011871	ENSUAMP00000025530	PLAC domain-containing protein.	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	0.899
ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSUAMP00000017830	TBX6	ENSUAMP00000017830	ENSUAMP00000031509	Uncharacterized protein.	T-box transcription factor 6.	0.426
ENSUAMP00000025530	ENSUAMP00000011871	ENSUAMP00000025530	ENSUAMP00000011871	P/Homo B domain-containing protein; Belongs to the peptidase S8 family.	PLAC domain-containing protein.	0.899
LHX1	TBX6	ENSUAMP00000036268	ENSUAMP00000031509	LIM homeobox 1.	T-box transcription factor 6.	0.445
MESP2	TBX6	ENSUAMP00000006770	ENSUAMP00000031509	Mesoderm posterior bHLH transcription factor 2.	T-box transcription factor 6.	0.750
PLD6	TDRD1	ENSUAMP00000006564	ENSUAMP00000011065	Phospholipase D family member 6.	Tudor domain containing 1.	0.410
PLD6	TDRKH	ENSUAMP00000006564	ENSUAMP00000025131	Phospholipase D family member 6.	Tudor and KH domain containing.	0.759
SMAD4	SMAD6	ENSUAMP00000018392	ENSUAMP00000026564	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.679
SMAD6	SMAD4	ENSUAMP00000026564	ENSUAMP00000018392	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.679
TBX6	ENSUAMP00000017830	ENSUAMP00000031509	ENSUAMP00000017830	T-box transcription factor 6.	Uncharacterized protein.	0.426
TBX6	LHX1	ENSUAMP00000031509	ENSUAMP00000036268	T-box transcription factor 6.	LIM homeobox 1.	0.445
TBX6	MESP2	ENSUAMP00000031509	ENSUAMP00000006770	T-box transcription factor 6.	Mesoderm posterior bHLH transcription factor 2.	0.750
TDRD1	PLD6	ENSUAMP00000011065	ENSUAMP00000006564	Tudor domain containing 1.	Phospholipase D family member 6.	0.410
TDRD1	TDRKH	ENSUAMP00000011065	ENSUAMP00000025131	Tudor domain containing 1.	Tudor and KH domain containing.	0.491
TDRD15	TDRKH	ENSUAMP00000004236	ENSUAMP00000025131	Tudor domain containing 15.	Tudor and KH domain containing.	0.474
TDRD6	TDRKH	ENSUAMP00000018870	ENSUAMP00000025131	Tudor domain containing 6.	Tudor and KH domain containing.	0.474
TDRKH	PLD6	ENSUAMP00000025131	ENSUAMP00000006564	Tudor and KH domain containing.	Phospholipase D family member 6.	0.759
TDRKH	TDRD1	ENSUAMP00000025131	ENSUAMP00000011065	Tudor and KH domain containing.	Tudor domain containing 1.	0.491