STRINGSTRING
WRNIP1 WRNIP1 POLE2 POLE2 POLD2 POLD2 ENSUAMP00000006705 ENSUAMP00000006705 POLK POLK ENSUAMP00000011011 ENSUAMP00000011011 ENSUAMP00000011715 ENSUAMP00000011715 ENSUAMP00000011742 ENSUAMP00000011742 ENSUAMP00000011763 ENSUAMP00000011763 SPRTN SPRTN PCNA PCNA ENSUAMP00000017619 ENSUAMP00000017619 POLD1 POLD1 POLI POLI REV3L REV3L SIRT1 SIRT1 POLDIP2 POLDIP2 TEX12 TEX12 CDKN2D CDKN2D ENSUAMP00000024046 ENSUAMP00000024046 ENSUAMP00000024049 ENSUAMP00000024049 MAD2L2 MAD2L2 ZBTB1 ZBTB1 WRN WRN DTL DTL VCP VCP ENSUAMP00000033611 ENSUAMP00000033611 ENSUAMP00000036251 ENSUAMP00000036251 SPATA22 SPATA22
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WRNIP1WRN helicase interacting protein 1. (663 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (507 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
ENSUAMP00000006705Uncharacterized protein. (266 aa)
POLKDNA polymerase kappa. (542 aa)
ENSUAMP00000011011Uncharacterized protein. (465 aa)
ENSUAMP00000011715DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (404 aa)
ENSUAMP00000011742DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (667 aa)
ENSUAMP00000011763DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (295 aa)
SPRTNSprT-like N-terminal domain. (509 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ENSUAMP00000017619UmuC domain-containing protein. (558 aa)
POLD1DNA polymerase. (1109 aa)
POLIDNA polymerase iota. (718 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (2648 aa)
SIRT1Sirtuin 1. (618 aa)
POLDIP2DNA polymerase delta interacting protein 2. (404 aa)
TEX12Testis expressed 12. (123 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
ENSUAMP00000024046Uncharacterized protein. (423 aa)
ENSUAMP00000024049Uncharacterized protein. (93 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
WRNWRN RecQ like helicase. (1363 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
ENSUAMP00000033611UmuC domain-containing protein. (188 aa)
ENSUAMP00000036251Uncharacterized protein. (182 aa)
SPATA22Spermatogenesis associated 22. (362 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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