45 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000010093	SUFU_C domain-containing protein. (81 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	MICAL2	Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1103 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (217 aa)
	CCDC103	Coiled-coil domain containing 103. (242 aa)
	ENSUAMP00000000600	Uncharacterized protein. (130 aa)
	ENSUAMP00000000737	Uncharacterized protein. (81 aa)
	SOX17	SRY-box transcription factor 17. (406 aa)
	ENSUAMP00000036217	Uncharacterized protein. (186 aa)
	IFT52	Intraflagellar transport 52. (467 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (823 aa)
	CLUAP1	Clusterin associated protein 1. (442 aa)
	NOTCH1	Notch receptor 1. (2547 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (430 aa)
	NOTCH2	Notch receptor 2. (2374 aa)
	AHI1	Abelson helper integration site 1. (1054 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (630 aa)
	TBX6	T-box transcription factor 6. (436 aa)
	LBX1	Ladybird homeobox 1. (281 aa)
	ENSUAMP00000030304	HH_signal domain-containing protein. (146 aa)
	ENG	Endoglin. (650 aa)
	ZIC3	Uncharacterized protein. (466 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (897 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (757 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (419 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	TBX20	T-box transcription factor 20. (448 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (218 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	C2CD3	C2 domain containing 3 centriole elongation regulator. (2209 aa)
	ENSUAMP00000000744	Uncharacterized protein. (157 aa)
	TBX2	T-box transcription factor 2. (697 aa)
	FOXH1	Forkhead box H1. (370 aa)
	ENSUAMP00000003258	Uncharacterized protein. (246 aa)
	ENSUAMP00000006083	Dynein assembly factor 1, axonemal. (316 aa)
	ENSUAMP00000007316	BMERB domain-containing protein. (677 aa)
	SRF	Serum response factor. (507 aa)
	ENSUAMP00000017830	Uncharacterized protein. (157 aa)
	MIB1	Mindbomb E3 ubiquitin protein ligase 1. (1041 aa)
	ENSUAMP00000017162	Uncharacterized protein. (137 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	ENSUAMP00000011008	Uncharacterized protein. (538 aa)
	ENSUAMP00000010997	TPR_REGION domain-containing protein. (150 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHI1	ARL13B	ENSUAMP00000033688	ENSUAMP00000034057	Abelson helper integration site 1.	ADP ribosylation factor like GTPase 13B.	0.556
ARL13B	AHI1	ENSUAMP00000034057	ENSUAMP00000033688	ADP ribosylation factor like GTPase 13B.	Abelson helper integration site 1.	0.556
ARL13B	C2CD3	ENSUAMP00000034057	ENSUAMP00000022517	ADP ribosylation factor like GTPase 13B.	C2 domain containing 3 centriole elongation regulator.	0.740
ARL13B	ENSUAMP00000000737	ENSUAMP00000034057	ENSUAMP00000000737	ADP ribosylation factor like GTPase 13B.	Uncharacterized protein.	0.596
ARL13B	ENSUAMP00000000744	ENSUAMP00000034057	ENSUAMP00000000744	ADP ribosylation factor like GTPase 13B.	Uncharacterized protein.	0.596
ARL13B	ENSUAMP00000010093	ENSUAMP00000034057	ENSUAMP00000010093	ADP ribosylation factor like GTPase 13B.	SUFU_C domain-containing protein.	0.455
ARL13B	ENSUAMP00000010997	ENSUAMP00000034057	ENSUAMP00000010997	ADP ribosylation factor like GTPase 13B.	TPR_REGION domain-containing protein.	0.634
ARL13B	ENSUAMP00000011008	ENSUAMP00000034057	ENSUAMP00000011008	ADP ribosylation factor like GTPase 13B.	Uncharacterized protein.	0.634
ARL13B	IFT52	ENSUAMP00000034057	ENSUAMP00000034702	ADP ribosylation factor like GTPase 13B.	Intraflagellar transport 52.	0.717
ARL13B	IHH	ENSUAMP00000034057	ENSUAMP00000028446	ADP ribosylation factor like GTPase 13B.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.741
ARL13B	PKD2	ENSUAMP00000034057	ENSUAMP00000029626	ADP ribosylation factor like GTPase 13B.	Polycystin 2, transient receptor potential cation channel.	0.748
ARL13B	SMO	ENSUAMP00000034057	ENSUAMP00000027495	ADP ribosylation factor like GTPase 13B.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.797
C2CD3	ARL13B	ENSUAMP00000022517	ENSUAMP00000034057	C2 domain containing 3 centriole elongation regulator.	ADP ribosylation factor like GTPase 13B.	0.740
CCDC103	ENSUAMP00000006083	ENSUAMP00000000326	ENSUAMP00000006083	Coiled-coil domain containing 103.	Dynein assembly factor 1, axonemal.	0.768
CCDC103	ENSUAMP00000036217	ENSUAMP00000000326	ENSUAMP00000036217	Coiled-coil domain containing 103.	Uncharacterized protein.	0.756
CITED2	HIF1A	ENSUAMP00000022802	ENSUAMP00000034536	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Hypoxia inducible factor 1 subunit alpha.	0.542
CLUAP1	ENSUAMP00000000737	ENSUAMP00000034414	ENSUAMP00000000737	Clusterin associated protein 1.	Uncharacterized protein.	0.984
CLUAP1	ENSUAMP00000000744	ENSUAMP00000034414	ENSUAMP00000000744	Clusterin associated protein 1.	Uncharacterized protein.	0.987
CLUAP1	ENSUAMP00000010997	ENSUAMP00000034414	ENSUAMP00000010997	Clusterin associated protein 1.	TPR_REGION domain-containing protein.	0.456
CLUAP1	ENSUAMP00000011008	ENSUAMP00000034414	ENSUAMP00000011008	Clusterin associated protein 1.	Uncharacterized protein.	0.456