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MSX1 | Msh homeobox 1. (303 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) | ||||
ANKRD1 | Ankyrin repeat domain 1. (319 aa) | ||||
MAPKAPK5 | MAPK activated protein kinase 5. (456 aa) | ||||
ENSUAMP00000001879 | Protein kinase domain-containing protein. (335 aa) | ||||
USP10 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (793 aa) | ||||
NUAK1 | NUAK family kinase 1. (671 aa) | ||||
CHD8 | Chromodomain helicase DNA binding protein 8. (1832 aa) | ||||
ENSUAMP00000006800 | Uncharacterized protein. (97 aa) | ||||
TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) | ||||
MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (492 aa) | ||||
BCL2L12 | BCL2 like 12. (323 aa) | ||||
RNF125 | Ring finger protein 125. (232 aa) | ||||
PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) | ||||
ENSUAMP00000010535 | Uncharacterized protein. (406 aa) | ||||
TP53BP2 | Tumor protein p53 binding protein 2. (1157 aa) | ||||
GATA1 | GATA binding protein 1. (413 aa) | ||||
SMYD2 | SET and MYND domain containing 2. (439 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta. (335 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
ENSUAMP00000013528 | U1-type domain-containing protein. (104 aa) | ||||
TEP1 | Telomerase associated protein 1. (2614 aa) | ||||
MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (252 aa) | ||||
TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (634 aa) | ||||
ENSUAMP00000015093 | Uncharacterized protein. (1064 aa) | ||||
ENSUAMP00000015102 | Uncharacterized protein. (121 aa) | ||||
PSME3 | Proteasome activator subunit 3. (254 aa) | ||||
ARMCX2 | Armadillo repeat containing X-linked 2. (615 aa) | ||||
ARMCX3 | Armadillo repeat containing X-linked 3. (379 aa) | ||||
RNF34 | Ring finger protein 34. (376 aa) | ||||
ENSUAMP00000019612 | Uncharacterized protein. (76 aa) | ||||
AXIN1 | Axin 1. (867 aa) | ||||
TRIM24 | Tripartite motif containing 24. (1021 aa) | ||||
TRIM29 | Tripartite motif containing 29. (585 aa) | ||||
CDKN2AIP | CDKN2A interacting protein. (571 aa) | ||||
SIRT1 | Sirtuin 1. (618 aa) | ||||
RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) | ||||
ENSUAMP00000023419 | SET domain-containing protein. (162 aa) | ||||
ENSUAMP00000023422 | ANK_REP_REGION domain-containing protein. (975 aa) | ||||
MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (495 aa) | ||||
TAF3 | TATA-box binding protein associated factor 3. (621 aa) | ||||
KMT5A | Lysine methyltransferase 5A. (327 aa) | ||||
HTT | Huntingtin. (3059 aa) | ||||
USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1055 aa) | ||||
ENSUAMP00000026418 | Uncharacterized protein. (83 aa) | ||||
ENSUAMP00000026725 | SEA domain-containing protein. (629 aa) | ||||
RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) | ||||
ENSUAMP00000027429 | Uncharacterized protein. (165 aa) | ||||
ENSUAMP00000027431 | Uncharacterized protein. (74 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1542 aa) | ||||
TP53RK | TP53 regulating kinase. (254 aa) | ||||
ZNF385A | Zinc finger protein 385A. (386 aa) | ||||
POU4F2 | POU domain protein. (408 aa) | ||||
RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (376 aa) | ||||
SETD7 | Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa) | ||||
CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) | ||||
CREBBP | CREB binding protein. (2333 aa) | ||||
EP300 | E1A binding protein p300. (2399 aa) | ||||
EHMT2 | Euchromatic histone lysine methyltransferase 2. (1294 aa) | ||||
BRD7 | Bromodomain containing 7. (674 aa) | ||||
NTRK3 | Tyrosine-protein kinase receptor. (784 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (823 aa) | ||||
ENSUAMP00000034862 | PSI domain-containing protein. (187 aa) | ||||
DUSP26 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa) | ||||
DAXX | Death domain associated protein. (756 aa) | ||||
NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (469 aa) |