STRINGSTRING
NOTCH1 NOTCH1 TIE1 TIE1 EMILIN1 EMILIN1 GATA4 GATA4 RB1 RB1 GATA5 GATA5 BMP2 BMP2 TBX20 TBX20 SOX9 SOX9 SMAD6 SMAD6 EFNA1 EFNA1 GATA3 GATA3 BMP4 BMP4 TNFRSF1A TNFRSF1A SLIT3 SLIT3 TNFRSF1B TNFRSF1B BMPR2 BMPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1Notch receptor 1. (2547 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1069 aa)
EMILIN1Elastin microfibril interfacer 1. (1020 aa)
GATA4GATA binding protein 4. (443 aa)
RB1RB transcriptional corepressor 1. (870 aa)
GATA5GATA binding protein 5. (414 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TBX20T-box transcription factor 20. (448 aa)
SOX9SRY-box transcription factor 9. (484 aa)
SMAD6Mothers against decapentaplegic homolog. (484 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
GATA3GATA binding protein 3. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TNFRSF1ATNF receptor superfamily member 1A. (502 aa)
SLIT3Slit guidance ligand 3. (1441 aa)
TNFRSF1BTNF receptor superfamily member 1B. (460 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (857 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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