13 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSUAMP00000000600	Uncharacterized protein. (130 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	TBX5	T-box transcription factor 5. (517 aa)
	ENSUAMP00000004725	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (253 aa)
	ENSUAMP00000004728	G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	BVES	Blood vessel epicardial substance. (323 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	ENSUAMP00000017162	Uncharacterized protein. (137 aa)
	ENSUAMP00000017830	Uncharacterized protein. (157 aa)
	ZIC3	Uncharacterized protein. (466 aa)
	ENG	Endoglin. (650 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	ENG	ENSUAMP00000015898	ENSUAMP00000030016	Bone morphogenetic protein 10.	Endoglin.	0.539
BMP10	TBX5	ENSUAMP00000015898	ENSUAMP00000002282	Bone morphogenetic protein 10.	T-box transcription factor 5.	0.468
ENG	BMP10	ENSUAMP00000030016	ENSUAMP00000015898	Endoglin.	Bone morphogenetic protein 10.	0.539
ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	Uncharacterized protein.	Uncharacterized protein.	0.671
ENSUAMP00000017830	ENSUAMP00000000600	ENSUAMP00000017830	ENSUAMP00000000600	Uncharacterized protein.	Uncharacterized protein.	0.671
TBX5	BMP10	ENSUAMP00000002282	ENSUAMP00000015898	T-box transcription factor 5.	Bone morphogenetic protein 10.	0.468
TBX5	WNT2	ENSUAMP00000002282	ENSUAMP00000009488	T-box transcription factor 5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.432
WNT2	TBX5	ENSUAMP00000009488	ENSUAMP00000002282	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor 5.	0.432