STRINGSTRING
METTL8 METTL8 NAA50 NAA50 GTF2B GTF2B TAF10 TAF10 GTF3C4 GTF3C4 EP300 EP300 KAT2A KAT2A CREBBP CREBBP KAT5 KAT5 NCOA3 NCOA3 KAT7 KAT7 ENSUAMP00000023849 ENSUAMP00000023849 ENSUAMP00000023511 ENSUAMP00000023511 NAA40 NAA40 BRCA2 BRCA2 CENPP CENPP KAT6A KAT6A KAT8 KAT8 ATF2 ATF2 ENSUAMP00000009805 ENSUAMP00000009805 HAT1 HAT1 KAT2B KAT2B MCM3AP MCM3AP ENSUAMP00000000300 ENSUAMP00000000300
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (406 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (199 aa)
GTF3C4General transcription factor IIIC subunit 4. (822 aa)
EP300E1A binding protein p300. (2399 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
CREBBPCREB binding protein. (2333 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
NCOA3Nuclear receptor coactivator. (1431 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (592 aa)
ENSUAMP00000023849Transcription initiation factor TFIID subunit. (1894 aa)
ENSUAMP00000023511Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2075 aa)
NAA40N(alpha)-acetyltransferase 40, NatD catalytic subunit. (216 aa)
BRCA2BRCA2 DNA repair associated. (3458 aa)
CENPPCentromere protein P. (276 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2004 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSUAMP00000009805H15 domain-containing protein. (216 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (378 aa)
KAT2BLysine acetyltransferase 2B. (629 aa)
MCM3APMinichromosome maintenance complex component 3 associated protein. (1999 aa)
ENSUAMP00000000300Bromo domain-containing protein. (84 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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