55 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (447 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
	NR2C2	Nuclear receptor subfamily 2 group C member 2. (629 aa)
	PGR	Progesterone receptor. (634 aa)
	VDR	Vitamin D receptor. (427 aa)
	RARA	Retinoic acid receptor alpha. (462 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (455 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (441 aa)
	ENSUAMP00000017524	Uncharacterized protein. (542 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (619 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (598 aa)
	RORB	RAR related orphan receptor B. (502 aa)
	NR2F6	Nuclear receptor subfamily 2 group F member 6. (388 aa)
	RARB	Retinoic acid receptor beta. (336 aa)
	AR	Androgen receptor. (905 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (481 aa)
	SMDT1	Single-pass membrane protein with aspartate rich tail 1. (107 aa)
	NR1I2	Nuclear receptor subfamily 1 group I member 2. (379 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (503 aa)
	ENSUAMP00000010069	Uncharacterized protein. (357 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (411 aa)
	ESR1	Estrogen receptor 1. (490 aa)
	ENSUAMP00000004918	Homeobox domain-containing protein. (230 aa)
	ENSUAMP00000004542	Uncharacterized protein. (171 aa)
	THRA	Thyroid hormone receptor alpha. (511 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (546 aa)
	ENSUAMP00000021070	Uncharacterized protein. (833 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	RORC	RAR related orphan receptor C. (517 aa)
	ESRRG	Estrogen related receptor gamma. (435 aa)
	ESRRB	Estrogen related receptor beta. (454 aa)
	RORA	RAR related orphan receptor A. (522 aa)
	HNF4G	Hepatocyte nuclear factor 4 gamma. (408 aa)
	RXRA	Retinoid X receptor alpha. (469 aa)
	THRB	Thyroid hormone receptor beta. (467 aa)
	ENSUAMP00000027844	Nuc_recep-AF1 domain-containing protein. (202 aa)
	ENSUAMP00000027845	Uncharacterized protein. (347 aa)
	ENSUAMP00000028186	Uncharacterized protein. (505 aa)
	ENSUAMP00000028801	BHLH domain-containing protein. (234 aa)
	ENSUAMP00000028802	Uncharacterized protein. (566 aa)
	NR3C1	Nuclear receptor subfamily 3 group C member 1. (781 aa)
	NR2C1	Nuclear receptor subfamily 2 group C member 1. (631 aa)
	NR6A1	Nuclear receptor subfamily 6 group A member 1. (454 aa)
	NR2F2	Nuclear receptor subfamily 2 group F member 2. (414 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3. (356 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	NR2F1	Nuclear receptor subfamily 2 group F member 1. (263 aa)
	ENSUAMP00000035192	Uncharacterized protein. (82 aa)
	ENSUAMP00000035193	Uncharacterized protein. (279 aa)
	ESRRA	Estrogen related receptor alpha. (422 aa)
	RXRB	Retinoid X receptor beta. (532 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (385 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (482 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ARNT	ENSUAMP00000013075	ENSUAMP00000012840	Androgen receptor.	Aryl hydrocarbon receptor nuclear translocator.	0.440
AR	ENSUAMP00000004918	ENSUAMP00000013075	ENSUAMP00000004918	Androgen receptor.	Homeobox domain-containing protein.	0.575
AR	ENSUAMP00000035192	ENSUAMP00000013075	ENSUAMP00000035192	Androgen receptor.	Uncharacterized protein.	0.440
AR	ENSUAMP00000035193	ENSUAMP00000013075	ENSUAMP00000035193	Androgen receptor.	Uncharacterized protein.	0.440
AR	ESR1	ENSUAMP00000013075	ENSUAMP00000006270	Androgen receptor.	Estrogen receptor 1.	0.587
AR	NR3C1	ENSUAMP00000013075	ENSUAMP00000029768	Androgen receptor.	Nuclear receptor subfamily 3 group C member 1.	0.582
AR	PGR	ENSUAMP00000013075	ENSUAMP00000000820	Androgen receptor.	Progesterone receptor.	0.618
AR	STAT3	ENSUAMP00000013075	ENSUAMP00000008772	Androgen receptor.	Signal transducer and activator of transcription.	0.627
ARNT	AR	ENSUAMP00000012840	ENSUAMP00000013075	Aryl hydrocarbon receptor nuclear translocator.	Androgen receptor.	0.440
ARNT	ENSUAMP00000021070	ENSUAMP00000012840	ENSUAMP00000021070	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.987
ARNT	ENSUAMP00000028801	ENSUAMP00000012840	ENSUAMP00000028801	Aryl hydrocarbon receptor nuclear translocator.	BHLH domain-containing protein.	0.863
ARNT	ENSUAMP00000028802	ENSUAMP00000012840	ENSUAMP00000028802	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.810
ARNT	ENSUAMP00000035193	ENSUAMP00000012840	ENSUAMP00000035193	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.899
ARNT	NR1I3	ENSUAMP00000012840	ENSUAMP00000033432	Aryl hydrocarbon receptor nuclear translocator.	Nuclear receptor subfamily 1 group I member 3.	0.437
ARNT	NR5A1	ENSUAMP00000012840	ENSUAMP00000033551	Aryl hydrocarbon receptor nuclear translocator.	Nuclear receptor subfamily 5 group A member 1.	0.596
ARNT	RORA	ENSUAMP00000012840	ENSUAMP00000024509	Aryl hydrocarbon receptor nuclear translocator.	RAR related orphan receptor A.	0.412
ARNT	THRA	ENSUAMP00000012840	ENSUAMP00000019322	Aryl hydrocarbon receptor nuclear translocator.	Thyroid hormone receptor alpha.	0.440
ARNT	THRB	ENSUAMP00000012840	ENSUAMP00000027527	Aryl hydrocarbon receptor nuclear translocator.	Thyroid hormone receptor beta.	0.464
ENSUAMP00000004542	ENSUAMP00000027844	ENSUAMP00000004542	ENSUAMP00000027844	Uncharacterized protein.	Nuc_recep-AF1 domain-containing protein.	0.486
ENSUAMP00000004542	ENSUAMP00000027845	ENSUAMP00000004542	ENSUAMP00000027845	Uncharacterized protein.	Uncharacterized protein.	0.533