21 items (Ursus americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SF3B2	Splicing factor 3b subunit 2. (910 aa)
	LSM7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (120 aa)
	ENSUAMP00000033230	RRM domain-containing protein. (125 aa)
	ENSUAMP00000033911	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
	SF3B5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	ZMAT5	Zinc finger matrin-type 5. (170 aa)
	ENSUAMP00000000623	Uncharacterized protein. (86 aa)
	ENSUAMP00000009903	Uncharacterized protein. (150 aa)
	SF3B3	Splicing factor 3b subunit 3. (1217 aa)
	SNRNP48	Small nuclear ribonucleoprotein U11/U12 subunit 48. (338 aa)
	ENSUAMP00000000999	RRM domain-containing protein. (126 aa)
	RBM41	RNA binding motif protein 41. (438 aa)
	ENSUAMP00000010072	Sm domain-containing protein. (105 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
	SNRNP35	Small nuclear ribonucleoprotein U11/U12 subunit 35. (246 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (117 aa)
	SNRNP25	Small nuclear ribonucleoprotein U11/U12 subunit 25. (123 aa)
	PHF5A	PHD finger protein 5A. (85 aa)
	SF3B1	Splicing factor 3b subunit 1. (1122 aa)
	ENSUAMP00000026187	Sm domain-containing protein. (72 aa)
	DHX15	DEAH-box helicase 15. (728 aa)

Your Current Organism:

Ursus americanus

NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHX15	ENSUAMP00000000623	ENSUAMP00000026644	ENSUAMP00000000623	DEAH-box helicase 15.	Uncharacterized protein.	0.932
DHX15	ENSUAMP00000000999	ENSUAMP00000026644	ENSUAMP00000000999	DEAH-box helicase 15.	RRM domain-containing protein.	0.643
DHX15	ENSUAMP00000009903	ENSUAMP00000026644	ENSUAMP00000009903	DEAH-box helicase 15.	Uncharacterized protein.	0.636
DHX15	ENSUAMP00000010072	ENSUAMP00000026644	ENSUAMP00000010072	DEAH-box helicase 15.	Sm domain-containing protein.	0.891
DHX15	ENSUAMP00000026187	ENSUAMP00000026644	ENSUAMP00000026187	DEAH-box helicase 15.	Sm domain-containing protein.	0.891
DHX15	ENSUAMP00000033230	ENSUAMP00000026644	ENSUAMP00000033230	DEAH-box helicase 15.	RRM domain-containing protein.	0.643
DHX15	ENSUAMP00000033911	ENSUAMP00000026644	ENSUAMP00000033911	DEAH-box helicase 15.	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.	0.927
DHX15	PHF5A	ENSUAMP00000026644	ENSUAMP00000029305	DEAH-box helicase 15.	PHD finger protein 5A.	0.981
DHX15	RBM41	ENSUAMP00000026644	ENSUAMP00000028326	DEAH-box helicase 15.	RNA binding motif protein 41.	0.636
DHX15	SF3B1	ENSUAMP00000026644	ENSUAMP00000024325	DEAH-box helicase 15.	Splicing factor 3b subunit 1.	0.968
DHX15	SF3B2	ENSUAMP00000026644	ENSUAMP00000026833	DEAH-box helicase 15.	Splicing factor 3b subunit 2.	0.896
DHX15	SF3B3	ENSUAMP00000026644	ENSUAMP00000007913	DEAH-box helicase 15.	Splicing factor 3b subunit 3.	0.910
DHX15	SF3B5	ENSUAMP00000026644	ENSUAMP00000035987	DEAH-box helicase 15.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.796
DHX15	SNRNP35	ENSUAMP00000026644	ENSUAMP00000015766	DEAH-box helicase 15.	Small nuclear ribonucleoprotein U11/U12 subunit 35.	0.546
DHX15	SNRNP48	ENSUAMP00000026644	ENSUAMP00000004026	DEAH-box helicase 15.	Small nuclear ribonucleoprotein U11/U12 subunit 48.	0.583
DHX15	SNRPD1	ENSUAMP00000026644	ENSUAMP00000016923	DEAH-box helicase 15.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.954
DHX15	SNRPD3	ENSUAMP00000026644	ENSUAMP00000013390	DEAH-box helicase 15.	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.	0.976
DHX15	ZMAT5	ENSUAMP00000026644	ENSUAMP00000019661	DEAH-box helicase 15.	Zinc finger matrin-type 5.	0.469
ENSUAMP00000000623	DHX15	ENSUAMP00000000623	ENSUAMP00000026644	Uncharacterized protein.	DEAH-box helicase 15.	0.932
ENSUAMP00000000623	ENSUAMP00000000999	ENSUAMP00000000623	ENSUAMP00000000999	Uncharacterized protein.	RRM domain-containing protein.	0.839