STRINGSTRING
FTCD FTCD SHMT2 SHMT2 MTHFD1 MTHFD1 AHCYL1 AHCYL1 ENSUAMP00000028538 ENSUAMP00000028538 FPGS FPGS CA4 CA4 ENSUAMP00000030831 ENSUAMP00000030831 CA6 CA6 ENSUAMP00000032448 ENSUAMP00000032448 TTC38 TTC38 CA9 CA9 CA10 CA10 MAT2A MAT2A ENSUAMP00000037302 ENSUAMP00000037302 CA8 CA8 ENSUAMP00000003272 ENSUAMP00000003272 AHCYL2 AHCYL2 ENSUAMP00000005677 ENSUAMP00000005677 ENSUAMP00000006222 ENSUAMP00000006222 MAT2B MAT2B CA5A CA5A CA7 CA7 AHCY AHCY CA14 CA14 CA3 CA3 CA11 CA11 SHMT1 SHMT1 CA1 CA1 SFXN1 SFXN1 MAT1A MAT1A ENSUAMP00000016283 ENSUAMP00000016283 ENSUAMP00000016284 ENSUAMP00000016284 CA12 CA12 MTHFD1L MTHFD1L ENSUAMP00000020367 ENSUAMP00000020367 MTHFD2 MTHFD2 GNMT GNMT SFXN3 SFXN3 ENSUAMP00000023340 ENSUAMP00000023340 ENSUAMP00000023441 ENSUAMP00000023441 CA13 CA13 ALDH1L1 ALDH1L1 MTHFR MTHFR ENSUAMP00000025515 ENSUAMP00000025515
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FTCDFormimidoyltransferase cyclodeaminase. (541 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (992 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
ENSUAMP00000028538Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (114 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (579 aa)
CA4Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (313 aa)
ENSUAMP00000030831Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (124 aa)
CA6Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (320 aa)
ENSUAMP000000324485-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa)
TTC38Tetratricopeptide repeat domain 38. (469 aa)
CA9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (451 aa)
CA10Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family. (311 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
ENSUAMP00000037302FTCD_N domain-containing protein. (197 aa)
CA8Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family. (159 aa)
ENSUAMP00000003272SHMT domain-containing protein. (59 aa)
AHCYL2Adenosylhomocysteinase like 2. (436 aa)
ENSUAMP00000005677Aldedh domain-containing protein. (169 aa)
ENSUAMP00000006222Carrier domain-containing protein. (376 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (324 aa)
CA5ACarbonic anhydrase 5A; Belongs to the alpha-carbonic anhydrase family. (372 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (445 aa)
CA14Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. (216 aa)
CA3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa)
CA11Carbonic anhydrase 11; Belongs to the alpha-carbonic anhydrase family. (332 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
CA1Carbonic anhydrase 1; Belongs to the alpha-carbonic anhydrase family. (261 aa)
SFXN1Sidoreflexin. (343 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
ENSUAMP00000016283THF_DHG_CYH_C domain-containing protein. (169 aa)
ENSUAMP00000016284THF_DHG_CYH domain-containing protein. (106 aa)
CA12Carbonic anhydrase 12; Belongs to the alpha-carbonic anhydrase family. (354 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (961 aa)
ENSUAMP00000020367Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (328 aa)
MTHFD2Uncharacterized protein. (350 aa)
GNMTGlycine N-methyltransferase. (295 aa)
SFXN3Sideroflexin 3. (290 aa)
ENSUAMP00000023340DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
ENSUAMP00000023441DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
CA13Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. (255 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (930 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (654 aa)
ENSUAMP00000025515THF_DHG_CYH domain-containing protein. (106 aa)
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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